Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kenneth H. Ely"'
Autor:
Bruce A Stanton, Kevin S Hsu, Kenneth H. Ely, Richard I. Enelow, Britton C. Goodale, Thomas H. Hampton
Publikováno v:
Toxicol Sci
Arsenic exposure via drinking water is a serious environmental health concern. Epidemiological studies suggest a strong association between prenatal arsenic exposure and subsequent childhood respiratory infections, as well as morbidity from respirato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc06101b77aef76287e954889edcf61f
https://doi.org/10.1093/toxsci/kfaa080
https://doi.org/10.1093/toxsci/kfaa080
Autor:
Kenneth H Ely, Mitsuo Matsuoka, Matthew P DeBerge, Jessica A Ruby, Jun Liu, Mark J Schneider, Yan Wang, Young S Hahn, Richard I Enelow
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108385 (2014)
Virus infection triggers a CD8(+) T cell response that aids in virus clearance, but also expresses effector functions that may result in tissue injury. CD8(+) T cells express a variety of activating and inhibiting ligands, though regulation of the ex
Externí odkaz:
https://doaj.org/article/a339d7fc234d4eeb85024396624e8fda
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79340 (2013)
Influenza infection in humans evokes a potent CD8(+) T-cell response, which is important for clearance of the virus but may also exacerbate pulmonary pathology. We have previously shown in mice that CD8(+) T-cell expression of TNF-α is required for
Externí odkaz:
https://doaj.org/article/b2a21b323dd2424e9f67d81f12babf68
Autor:
Jacob E. Kohlmeier, Kenneth H. Ely, Lisa M. Connor, Alan D. Roberts, Eric J. Yager, David L. Woodland, Marcia A. Blackman
Publikováno v:
Handbook of Immunosenescence ISBN: 9783319645971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65af8321f72ba824574a86f481fcc665
https://doi.org/10.1007/978-3-319-64597-1_49-1
https://doi.org/10.1007/978-3-319-64597-1_49-1
Publikováno v:
The Journal of Immunology. 192:5839-5851
TNF-α is a pleotropic cytokine that has both proinflammatory and anti-inflammatory functions during influenza infection. TNF-α is first expressed as a transmembrane protein that is proteolytically processed to release a soluble form. Transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f0fb3006a4a02d73be68c18cc0fb10
https://doi.org/10.4049/jimmunol.1302729
https://doi.org/10.4049/jimmunol.1302729
Publikováno v:
Environmental Health Perspectives
Background Arsenic exposure is a significant worldwide environmental health concern. We recently reported that 5-week exposure to environmentally relevant levels (10 and 100 ppb) of As in drinking water significantly altered components of the innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bf81cba47e2cc9ed451ba28e3c8983
http://europepmc.org/articles/PMC2737023
http://europepmc.org/articles/PMC2737023
Autor:
Jacob E. Kohlmeier, Marcia A. Blackman, Kenneth H. Ely, David L. Woodland, Alan D. Roberts, Mushtaq Ahmed, Susan T. Wittmer
Publikováno v:
The Journal of Immunology. 179:3535-3542
Increasing age is associated with the development of CD8+ T cell clonal expansions (TCE) that can dominate the peripheral T cell repertoire and interfere with immune responses to infection and vaccination. Some TCE are driven by chronic infections, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75eac0b433b63c51f3f1762637ae06bb
https://doi.org/10.4049/jimmunol.179.6.3535
https://doi.org/10.4049/jimmunol.179.6.3535
Publikováno v:
Experimental Gerontology. 42:427-431
The capacity of the immune system to mediate effective immune responses to pathogens declines with age. In the case of immune responses to newly encountered antigens, several studies have demonstrated that this decline reflects both a loss of naïve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbffc297395c97e389ef6c62ce10cef0
https://doi.org/10.1016/j.exger.2006.11.017
https://doi.org/10.1016/j.exger.2006.11.017
Publikováno v:
The Journal of Experimental Medicine
Although the absolute number of memory CD8+ T cells established in the spleen following antigen encounter remains stable for many years, the relative capacity of these cells to mediate recall responses is not known. Here we used a dual adoptive trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410ec2208f0c9e18c43668f820f6d4eb
https://doi.org/10.1084/jem.20050137
https://doi.org/10.1084/jem.20050137