Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Kenneth H Yu"'
Autor:
Louise M Fanchon, James Russell, Nagavarakishore Pillarsetty, Isabella O'Donoghue, Kishore Gangangari, Kenneth H Yu, John L Humm
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231745 (2020)
PurposeTo develop a technique to compare the intra-tumoral distribution of the drug gemcitabine, its surrogate [18F]-fluoroarabinocytosine ([18F]-FAC) and related chemotherapeutics 5-FU and capecitabine in a pre-clinical model of pancreatic ductal ad
Externí odkaz:
https://doaj.org/article/7adf9221d4bb4d8e964ed7d9acc68bdd
Publikováno v:
Aerospace, Vol 11, Iss 7, p 559 (2024)
A micro-pulse detonation engine (μPDE) was designed and installed to a direct-connect scramjet combustor of Pusan National University (PNU-DCSC). The active excitation on the scramjet combustor was experimentally studied using the μPDE operating at
Externí odkaz:
https://doaj.org/article/2ab3add7e7bf415d9624541a5465d159
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9496-9505 (2023)
Abstract Background Subgroup analyses of the NAPOLI‐1 study identified that among patients who were irinotecan naïve prior to entering the clinical trial, a survival benefit was observed between the study arm and control arm. This treatment benefi
Externí odkaz:
https://doaj.org/article/0f119c35950048d1824f7cadc9131a94
Publikováno v:
Cancer Medicine, Vol 9, Iss 22, Pp 8480-8490 (2020)
ABSTRACT Background Real‐world practice patterns, treatment sequencing, and outcomes in patients with metastatic pancreatic cancer remain unclear. Previous research indicates that the likelihood of patients with metastatic pancreatic cancer receivi
Externí odkaz:
https://doaj.org/article/9a32188badb443708867cdcac3ea311a
Autor:
Zishuo Ian Hu, Johanna C. Bendell, Andrea Bullock, Noelle K. LoConte, Hassan Hatoum, Paul Ritch, Hugo Hool, Joseph W. Leach, James Sanchez, Davendra P. S. Sohal, John Strickler, Ravindranath Patel, Andrea Wang‐Gillam, Irfan Firdaus, Kenneth H. Yu, Ann M. Kapoun, Eric Holmgren, Lei Zhou, Jakob Dupont, Vincent Picozzi, Vaibhav Sahai, Eileen M. O'Reilly
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 5148-5157 (2019)
Abstract Purpose Notch signaling dysregulation is implicated in the development of pancreatic adenocarcinoma (PDAC). Tarextumab is a fully human IgG2 antibody that inhibits Notch2/3 receptors. Patients and Methods Aphase 2, randomized, placebo‐cont
Externí odkaz:
https://doaj.org/article/65d331d0de7c4b2799fe21f23c85e265
Autor:
Danielle C. Glassman, Randze L. Palmaira, Christina M. Covington, Avni M. Desai, Geoffrey Y. Ku, Jia Li, James J. Harding, Anna M. Varghese, Eileen M. O’Reilly, Kenneth H. Yu
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Effective treatment options for advanced pancreatic cancer are finite. NAPOLI-1, a phase III randomized trial, demonstrated the efficacy of nanoliposomal irinotecan with fluorouracil/leucovorin (nal-IRI + 5-FU/LV) for the treatmen
Externí odkaz:
https://doaj.org/article/d76611a5fe52415d8c44ebc634314e01
Autor:
David A. Tuveson, Paul Robson, Andrea Califano, Elizabeth M. Jaffee, Jonathan Preall, Youngkyu Park, Christopher L. Wolfgang, Yuan Hao, Kenneth H. Yu, Dannielle D. Engle, Todd D. Armstrong, Santhosh Sivajothi, Matthew S. Lucito, Giulia Biffi, Pascal Belleau, Jonathan A. Teinor, Richard A. Burkhart, Elise T. Courtois, William F. Flynn, Pasquale Laise, Mohan Bolisetty, Ela Elyada
Supplementary Table S1 shows patient information, Supplementary Table S2 shows cell numbers analyzed from each human PDAC sample, Supplementary Table S3 shows statistics of the clustering analysis of the human PDAC single cell RNA sequencing, Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537a71e519160c84fb5e054e05d8c6ba
https://doi.org/10.1158/2159-8290.22536665.v1
https://doi.org/10.1158/2159-8290.22536665.v1
Autor:
David A. Tuveson, Paul Robson, Andrea Califano, Elizabeth M. Jaffee, Jonathan Preall, Youngkyu Park, Christopher L. Wolfgang, Yuan Hao, Kenneth H. Yu, Dannielle D. Engle, Todd D. Armstrong, Santhosh Sivajothi, Matthew S. Lucito, Giulia Biffi, Pascal Belleau, Jonathan A. Teinor, Richard A. Burkhart, Elise T. Courtois, William F. Flynn, Pasquale Laise, Mohan Bolisetty, Ela Elyada
Supplementary Table S16 shows protein activity of transcription factors in human CAFs, as analyzed by VIPER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27950d942eed3e300703f26af92688e1
https://doi.org/10.1158/2159-8290.22536695.v1
https://doi.org/10.1158/2159-8290.22536695.v1
Autor:
David A. Tuveson, Paul Robson, Andrea Califano, Elizabeth M. Jaffee, Jonathan Preall, Youngkyu Park, Christopher L. Wolfgang, Yuan Hao, Kenneth H. Yu, Dannielle D. Engle, Todd D. Armstrong, Santhosh Sivajothi, Matthew S. Lucito, Giulia Biffi, Pascal Belleau, Jonathan A. Teinor, Richard A. Burkhart, Elise T. Courtois, William F. Flynn, Pasquale Laise, Mohan Bolisetty, Ela Elyada
Cancer-associated fibroblasts (CAF) are major players in the progression and drug resistance of pancreatic ductal adenocarcinoma (PDAC). CAFs constitute a diverse cell population consisting of several recently described subtypes, although the extent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05668eed082a8964c856d8103f8ad225
https://doi.org/10.1158/2159-8290.c.6548204.v1
https://doi.org/10.1158/2159-8290.c.6548204.v1
Autor:
David A. Tuveson, Steven Gallinger, Alexander Krasnitz, Jennifer Knox, Richard Moffitt, Julie M. Wilson, Sandra E. Fischer, Benjamin Hubert, Christopher R. Vakoc, Ellen Li, Kenneth H. Yu, Christopher L. Wolfgang, Allyson Ocean, Craig Devoe, James M. Crawford, Edward Kim, Faiyaz Notta, Grainne M. O'Kane, Michael A. Hollingsworth, Jonathan R. Brody, Paul M. Grandgenett, Jonathan M. Buscaglia, Dominick J. DiMaio, Jean L. Grem, Phyllis A. Gimotty, Jordan M. Winter, James D. Sullivan, William Nealon, Divyesh V. Sejpal, Peter Allen, Juan Carlos Bucobo, Maoxin Wu, Joseph Kim, Aaron Sasson, Brian M. Wolpin, Andrew J. Aguirre, Elizabeth Thompson, Ralph H. Hruban, Laura D. Wood, Hans Clevers, Christine A. Iacobuzio-Donahue, Gokce Askan, Nicolas LeComte, Else Driehuis, Laura Martello, Cinthya Y. Lowder, Austin B. Goetz, Rashesh Sanghvi, Minita Shah, Nicolas Robine, Kanika Arora, Molly Johnson, Jasmine C. Huynh, Ammar A. Javed, Randze Lerie D. Palmaira, Joseph F. LaComb, Michelle Ma, Hardik Patel, C. Megan Young, Koji Miyabayashi, Gun-Ho Jang, Robert E. Denroche, Richard A. Burkhart, Fieke E. M. Froeling, Tim D. D. Somerville, Astrid Deschênes, Dennis Plenker, Dannielle D. Engle, Pascal Belleau, Hervé Tiriac
Supplemental Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4b9db9fc893e295d2cada7f880c78f
https://doi.org/10.1158/2159-8290.22533064.v1
https://doi.org/10.1158/2159-8290.22533064.v1