Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Kenneth H Yu"'
Publikováno v:
Aerospace, Vol 11, Iss 7, p 559 (2024)
A micro-pulse detonation engine (μPDE) was designed and installed to a direct-connect scramjet combustor of Pusan National University (PNU-DCSC). The active excitation on the scramjet combustor was experimentally studied using the μPDE operating at
Externí odkaz:
https://doaj.org/article/2ab3add7e7bf415d9624541a5465d159
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9496-9505 (2023)
Abstract Background Subgroup analyses of the NAPOLI‐1 study identified that among patients who were irinotecan naïve prior to entering the clinical trial, a survival benefit was observed between the study arm and control arm. This treatment benefi
Externí odkaz:
https://doaj.org/article/0f119c35950048d1824f7cadc9131a94
Publikováno v:
Cancer Medicine, Vol 10, Iss 24, Pp 8934-8943 (2021)
Abstract Background Many real‐world studies of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) are restricted to single centers, limiting the generalizability of their insights. This study aimed to identify important population‐
Externí odkaz:
https://doaj.org/article/7c77468f8c8342cc8ada33cd4bc89d92
Autor:
Suhasini Joshi, Erica DaGama Gomes, Tai Wang, Adriana Corben, Tony Taldone, Srinivasa Gandu, Chao Xu, Sahil Sharma, Salma Buddaseth, Pengrong Yan, Lon Yin L. Chan, Askan Gokce, Vinagolu K. Rajasekhar, Lisa Shrestha, Palak Panchal, Justina Almodovar, Chander S. Digwal, Anna Rodina, Swathi Merugu, NagaVaraKishore Pillarsetty, Vlad Miclea, Radu I. Peter, Wanyan Wang, Stephen D. Ginsberg, Laura Tang, Marissa Mattar, Elisa de Stanchina, Kenneth H. Yu, Maeve Lowery, Olivera Grbovic-Huezo, Eileen M. O’Reilly, Yelena Janjigian, John H. Healey, William R. Jarnagin, Peter J. Allen, Chris Sander, Hediye Erdjument-Bromage, Thomas A. Neubert, Steven D. Leach, Gabriela Chiosis
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-20 (2021)
Joshi, Gomes et al. employ a chemical modulation approach of the cellular interactome to a hyperconnectivity state and show association with the increased response of pancreatic cancer cell lines to specific drugs, including those that target the MAP
Externí odkaz:
https://doaj.org/article/c73d69998238486ba39d6f85c901b64d
Publikováno v:
Cancer Medicine, Vol 9, Iss 22, Pp 8480-8490 (2020)
ABSTRACT Background Real‐world practice patterns, treatment sequencing, and outcomes in patients with metastatic pancreatic cancer remain unclear. Previous research indicates that the likelihood of patients with metastatic pancreatic cancer receivi
Externí odkaz:
https://doaj.org/article/9a32188badb443708867cdcac3ea311a
Autor:
Kenneth H. Yu, Andrew E. Hendifar, Olatunji B. Alese, Amber Draper, Maen Abdelrahim, Ethan Burns, Gazala Khan, Paul Cockrum, Rachel H. Bhak, Catherine Nguyen, Maral DerSarkissian, Mei Sheng Duh, Nathan Bahary
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe NAPOLI-1 trial demonstrated that liposomal irinotecan in combination with fluorouracil (5-FU) and leucovorin (LV) prolonged survival with a manageable safety profile in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) p
Externí odkaz:
https://doaj.org/article/43a57f71459e47a9b5b2ba864581164f
Autor:
Zishuo Ian Hu, Johanna C. Bendell, Andrea Bullock, Noelle K. LoConte, Hassan Hatoum, Paul Ritch, Hugo Hool, Joseph W. Leach, James Sanchez, Davendra P. S. Sohal, John Strickler, Ravindranath Patel, Andrea Wang‐Gillam, Irfan Firdaus, Kenneth H. Yu, Ann M. Kapoun, Eric Holmgren, Lei Zhou, Jakob Dupont, Vincent Picozzi, Vaibhav Sahai, Eileen M. O'Reilly
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 5148-5157 (2019)
Abstract Purpose Notch signaling dysregulation is implicated in the development of pancreatic adenocarcinoma (PDAC). Tarextumab is a fully human IgG2 antibody that inhibits Notch2/3 receptors. Patients and Methods Aphase 2, randomized, placebo‐cont
Externí odkaz:
https://doaj.org/article/65d331d0de7c4b2799fe21f23c85e265
Autor:
Louise M Fanchon, James Russell, Nagavarakishore Pillarsetty, Isabella O'Donoghue, Kishore Gangangari, Kenneth H Yu, John L Humm
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231745 (2020)
PurposeTo develop a technique to compare the intra-tumoral distribution of the drug gemcitabine, its surrogate [18F]-fluoroarabinocytosine ([18F]-FAC) and related chemotherapeutics 5-FU and capecitabine in a pre-clinical model of pancreatic ductal ad
Externí odkaz:
https://doaj.org/article/7adf9221d4bb4d8e964ed7d9acc68bdd
Autor:
Danielle C. Glassman, Randze L. Palmaira, Christina M. Covington, Avni M. Desai, Geoffrey Y. Ku, Jia Li, James J. Harding, Anna M. Varghese, Eileen M. O’Reilly, Kenneth H. Yu
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Effective treatment options for advanced pancreatic cancer are finite. NAPOLI-1, a phase III randomized trial, demonstrated the efficacy of nanoliposomal irinotecan with fluorouracil/leucovorin (nal-IRI + 5-FU/LV) for the treatmen
Externí odkaz:
https://doaj.org/article/d76611a5fe52415d8c44ebc634314e01
Autor:
David A. Tuveson, Paul Robson, Andrea Califano, Elizabeth M. Jaffee, Jonathan Preall, Youngkyu Park, Christopher L. Wolfgang, Yuan Hao, Kenneth H. Yu, Dannielle D. Engle, Todd D. Armstrong, Santhosh Sivajothi, Matthew S. Lucito, Giulia Biffi, Pascal Belleau, Jonathan A. Teinor, Richard A. Burkhart, Elise T. Courtois, William F. Flynn, Pasquale Laise, Mohan Bolisetty, Ela Elyada
Supplementary Table S1 shows patient information, Supplementary Table S2 shows cell numbers analyzed from each human PDAC sample, Supplementary Table S3 shows statistics of the clustering analysis of the human PDAC single cell RNA sequencing, Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537a71e519160c84fb5e054e05d8c6ba
https://doi.org/10.1158/2159-8290.22536665.v1
https://doi.org/10.1158/2159-8290.22536665.v1
