Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kenneth G. Trieu"'
Autor:
Kenneth G. Trieu, Shih-Ying Tsai, Markus Eberl, Virginia Ju, Noah C. Ford, Owen J. Doane, Jamie K. Peterson, Natalia A. Veniaminova, Marina Grachtchouk, Paul W. Harms, Fredrik J. Swartling, Andrzej A. Dlugosz, Sunny Y. Wong
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110779- (2022)
Summary: Basal cell carcinomas (BCCs) frequently possess immense mutational burdens; however, the functional significance of most of these mutations remains unclear. Here, we report that loss of Ptch1, the most common mutation that activates upstream
Externí odkaz:
https://doaj.org/article/d668688d821c46339e004ee32ee87993
Autor:
Kenneth G. Trieu, Shih-Ying Tsai, Markus Eberl, Virginia Ju, Noah C. Ford, Owen J. Doane, Jamie K. Peterson, Natalia A. Veniaminova, Marina Grachtchouk, Paul W. Harms, Fredrik J. Swartling, Andrzej A. Dlugosz, Sunny Y. Wong
Basal cell carcinomas (BCCs) frequently possess immense mutational burdens; however, the functional significance of most of these mutations remains unclear. Here, we report that loss of Ptch1, the most common mutation that activates upstream Hedgehog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e589138c1e4f17cd4cc1c7e247632eb0
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-476536
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-476536
Autor:
Kenneth G. Trieu, Wei Wang, Kruti R. Patel, Xingbin Ai, Christina J. Yung, Thomas S Buttrick, Wassim Elyaman, Samia J. Khoury
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
T helper 9 (Th9) cells are effector CD4+ T cells that are characterized by the production of interleukin-9 (IL-9) and have been associated with allergic responses. Here, we found that the expression of the transcription factor forkhead box O1 (Foxo1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dd24f984324fb7a24e37fbfab9eee9
http://link.springer.com/article/10.1038/s41598-018-19315-z
http://link.springer.com/article/10.1038/s41598-018-19315-z
Publikováno v:
The FASEB Journal. 31:4335-4346
Asthma often progresses into adulthood from early-life episodes of adverse environmental exposures. However, how the injury to developing lungs contributes to the pathophysiology of persistent asthma remains poorly understood. In this study, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d794e7454878353094e8587ec2c8bf8
https://doi.org/10.1096/fj.201700186r
https://doi.org/10.1096/fj.201700186r
Autor:
Alan Fine, Fengzhi Shao, Kenneth G. Trieu, Wei Wang, Xingbin Ai, Jonathan A. Cohen, Juliana Barrios, Yan Bai, Antonia Wallrapp, Vijay K. Kuchroo, Matthew R. Jones, Nandini Krishnamoorthy
Publikováno v:
Immunity. 51(6)
Summary Young children are more susceptible to developing allergic asthma than adults. As neural innervation of the peripheral tissue continues to develop after birth, neurons may modulate tissue inflammation in an age-related manner. Here we showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf924740b006d5d29ab2de68c8af895
https://pubmed.ncbi.nlm.nih.gov/31851903
https://pubmed.ncbi.nlm.nih.gov/31851903
Autor:
Yan Bai, Kenneth G. Trieu, Juliana Barrios, Matthew R. Jones, Xingbin Ai, Nandini Krishnamoorthy, Wei Wang, Jonathan A. Cohen, Alan Fine
Publikováno v:
SSRN Electronic Journal.
As neural innervation of the peripheral tissue continues to develop after birth, neurons may modulate tissue inflammation in an age-related manner. Herein, we investigated the role of the developing nervous system in the asthma diathesis that charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0a09a77ab57d419d17cc9a2fa92fb6
https://doi.org/10.2139/ssrn.3389887
https://doi.org/10.2139/ssrn.3389887
Autor:
Liu Yang, Kellee R. Siegfried, Gerardo Jiménez, Kenneth G. Trieu, Louise Y. Cheng, Shu Kondo, Francesca Froldi, Sayantanee Paul, Stanislav Y. Shvartsman, Kaitlyn A. Webster, Marta Forés, Alexey Veraksa, Lucas G. Dent, Kieran F. Harvey
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The transcriptional repressor Capicua (Cic) controls tissue patterning and restricts organ growth, and has been recently implicated in several cancers. Cic has emerged as a primary sensor of signaling downstream of the receptor tyrosine kinase (RTK)/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29c2be9cd54f7a8e66639a2e386d844
https://doi.org/10.1073/pnas.1609417113
https://doi.org/10.1073/pnas.1609417113