Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Kenneth F, Ilett"'
Autor:
Kay Kose, Sam Salman, Madhu Page-Sharp, Kenneth F. Ilett, Timothy M. E. Davis, Peter Siba, Stephen J. Rogerson, Francesca Baiwog, Ivo Mueller, Harin Karunajeewa
Publikováno v:
International journal of antimicrobial agents. 50(4)
Despite extensive use and accumulated evidence of safety, there have been few pharmacokinetic studies from which appropriate chloroquine (CQ) dosing regimens could be developed specifically for pregnant women. Such optimised CQ-based regimens, used a
Autor:
Facundo Garcia Bournissen, Anna Taddio, Judith H. Kristensen, Kenneth F. Ilett, Izhar Wallach, Evan J. Begg, Reo Tanoshima, Yusuke Tanigawara, Shinya Ito
Publikováno v:
British Journal of Clinical Pharmacology. 78:918-928
Aims Population pharmacokinetic (pop PK) modelling can be used for PK assessment of drugs in breast milk. However, complex mechanistic modelling of a parent and an active metabolite using both blood and milk samples is challenging. We aimed to develo
Autor:
Madhu Page-Sharp, Susan Griffin, Sam Salman, Timothy M. E. Davis, Peter Siba, Kenneth F. Ilett, Harin Karunajeewa, Ivo Mueller, Stephen J. Rogerson, Francisca Baiwog
Publikováno v:
Antimicrobial agents and chemotherapy. 61(5)
Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy remains to be established, particularly when coadministered with azithromycin (AZI). To further characterize SP pharmacokinetics in pregnancy, plasma c
Publikováno v:
Breastfeeding Medicine. 7:269-274
The aim of the present study was to estimate the dose of buprenorphine and its primary metabolite norbuprenorphine that a breastfed infant would receive during maternal maintenance treatment with buprenorphine.Seven pregnant opioid-dependent women ta
Autor:
Sean J. O'Halloran, Kylie Davies, Sam Salman, Bruce Hullett, Kenneth F. Ilett, Deborah Peirce
Publikováno v:
University of Western Australia
Background Parecoxib is a cyclooxygenase-2 selective inhibitor used in management of postoperative pain in adults. This study aimed to provide pediatric pharmacokinetic information for parecoxib and its active metabolite valdecoxib. Methods Thirty-ei
Publikováno v:
Australian and New Zealand Journal of Obstetrics and Gynaecology. 52:342-347
Background Buprenorphine, a partial opioid agonist used in treating opioid dependence, is not approved in Australia for use in pregnancy. Nevertheless, many pregnant women choose to remain on the drug. Aim To investigate cord/maternal transfer ratios
Autor:
Susan Griffin, Ivo Mueller, Madhu Page-Sharp, Kaye Kose, Peter Siba, Timothy M. E. Davis, Kenneth F. Ilett, Sam Salman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:5306-5313
There are sparse published data relating to the pharmacokinetic properties of artemether, lumefantrine, and their active metabolites in children, especially desbutyl-lumefantrine. We studied 13 Papua New Guinean children aged 5 to 10 years with uncom
Autor:
Brioni R. Moore, Madhu Page-Sharp, Jeffrey D. Jago, Kenneth F. Ilett, Kevin T. Batty, Jillian R. Stoney
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:3899-3907
Chloroquine (CQ) is an important antimalarial drug for the treatment of special patient groups and as a comparator for preclinical testing of new drugs. Pharmacokinetic data for CQ in animal models are limited; thus, we conducted a three-part investi
Publikováno v:
International Journal of Obstetric Anesthesia. 20:128-134
Background There is no information about the distribution of pethidine into breast milk and/or exposure of the breastfed infant during pethidine patient-controlled epidural analgesia after caesarean delivery. Methods We conducted an observational stu
Publikováno v:
Breastfeeding Medicine. 6:85-88
This case describes the transfer of the antipsychotic drug amisulpride into milk and the estimation of infant exposure via breastfeeding. The dyad investigated was a 28-year-old lactating woman and her 13-month-old daughter. The woman had been taking