Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kenneth E. Prehoda"'
Actin-dependent membrane polarization reveals the mechanical nature of the neuroblast polarity cycle
Autor:
Bryce LaFoya, Kenneth E. Prehoda
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109146- (2021)
Summary: The Par complex directs fate-determinant segregation from the apical membrane of asymmetrically dividing Drosophila neuroblasts. While the physical interactions that recruit the Par complex have been extensively studied, little is known abou
Externí odkaz:
https://doaj.org/article/0f2bd2fb36604615b545d87ee4b0948d
Autor:
Chet Huan Oon, Kenneth E Prehoda
Publikováno v:
eLife, Vol 10 (2021)
The Par complex dynamically polarizes to the apical cortex of asymmetrically dividing Drosophila neuroblasts where it directs fate determinant segregation. Previously, we showed that apically directed cortical movements that polarize the Par complex
Externí odkaz:
https://doaj.org/article/4a4feff74aec43b4b4a3ef6744b3a073
Autor:
Bryce LaFoya, Kenneth E. Prehoda
Publikováno v:
Developmental Cell.
Autor:
Chet Huan Oon, Kenneth E Prehoda
Publikováno v:
eLife, Vol 8 (2019)
During the asymmetric divisions of Drosophila neuroblasts, the Par polarity complex cycles between the cytoplasm and an apical cortical domain that restricts differentiation factors to the basal cortex. We used rapid imaging of the full cell volume t
Externí odkaz:
https://doaj.org/article/f8923051bea04cbe826b1a11571f8e53
Publikováno v:
eLife, Vol 6 (2017)
Asymmetric division generates cellular diversity by producing daughter cells with different fates. In animals, the mitotic spindle aligns with Par complex polarized fate determinants, ensuring that fate determinant cortical domains are bisected by th
Externí odkaz:
https://doaj.org/article/017e4510a527485bb460019b15553120
Autor:
Elizabeth Vargas, Kenneth E. Prehoda
Publikováno v:
The Journal of biological chemistry. 299(1)
The Par complex polarizes diverse animal cells through the concerted action of multiple regulators. Binding to the multi-PDZ domain containing protein Par-3 couples the complex to cortical flows that construct the Par membrane domain. Once localized
Autor:
Bryce LaFoya, Kenneth E. Prehoda
SummaryThe asymmetric divisions ofDrosophilaneural stem cells (NSCs) produce unequally sized siblings, with most volume directed into the sibling that retains the NSC fate. Sibling size asymmetry results from preferential expansion of the NSC sibling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a021dbcdc983212cb92d8ffa94e3a222
https://doi.org/10.1101/2022.05.03.490551
https://doi.org/10.1101/2022.05.03.490551
Recruitment of the Par complex protein atypical Protein Kinase C (aPKC) to a specific membrane domain is a key step in the polarization of animal cells. While numerous proteins and phospholipids interact with aPKC, how these interactions cooperate to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b89559abb0fa6fb82a9b90d0af4a092
https://doi.org/10.1101/2022.01.01.474707
https://doi.org/10.1101/2022.01.01.474707
Autor:
Douglas P Anderson, Dustin S Whitney, Victor Hanson-Smith, Arielle Woznica, William Campodonico-Burnett, Brian F Volkman, Nicole King, Joseph W Thornton, Kenneth E Prehoda
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/d163b99aabce4d4e869921863c92c4b2