Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kenneth D. Tucker"'
Autor:
Vinayaka Kotraiah, Timothy W. Phares, Frances E. Terry, Pooja Hindocha, Sarah E. Silk, Carolyn M. Nielsen, Leonard Moise, Kenneth D. Tucker, Rebecca Ashfield, William D. Martin, Anne S. De Groot, Simon J. Draper, Gabriel M. Gutierrez, Amy R. Noe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The hurdles to effective blood stage malaria vaccine design include immune evasion tactics used by the parasite such as redundant invasion pathways and antigen variation among circulating parasite strains. While blood stage malaria vaccine developmen
Externí odkaz:
https://doaj.org/article/2deefbdc3cd44a348943f7cc2e674f49
Autor:
Amy R. Noe, Frances E. Terry, Brian C. Schanen, Emily Sassano, Pooja Hindocha, Timothy W. Phares, Leonard Moise, Jayne M. Christen, Kenneth D. Tucker, Vinayaka Kotraiah, Donald R. Drake, William D. Martin, Anne S. De Groot, Gabriel M. Gutierrez
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
An effective malaria vaccine must prevent disease in a range of populations living in regions with vastly different transmission rates and protect against genetically-diverse Plasmodium falciparum (Pf) strains. The protective efficacy afforded by the
Externí odkaz:
https://doaj.org/article/fef88e5b7d31426fb7aaaf98a3dfc878
Autor:
Kenneth D. Tucker, Brian C. Schanen, Timothy W. Phares, Emily Sassano, Frances E. Terry, Pooja Hindocha, Leonard Moise, Vinayaka Kotraiah, William D. Martin, Anne S. De Groot, Donald R. Drake, Gabriel M. Gutierrez, Amy R. Noe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunization with radiation-attenuated sporozoites (RAS) has been shown to protect against malaria infection, primarily through CD8 T cell responses, but protection is limited based on parasite strain. Therefore, while CD8 T cells are an ideal effect
Externí odkaz:
https://doaj.org/article/839ca3ed3a7e4d638b64a64cda4d2406
Autor:
Vinayaka Kotraiah, Timothy W. Phares, Cecille D. Browne, James Pannucci, Marc Mansour, Amy R. Noe, Kenneth D. Tucker, Jayne M. Christen, Charles Reed, Alecia MacKay, Genevieve M. Weir, Rajkannan Rajagopalan, Marianne M. Stanford, Chun-Shiang Chung, Alfred Ayala, Jing Huang, Moriya Tsuji, Gabriel M. Gutierrez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Many pathogens use the same immune evasion mechanisms as cancer cells. Patients with chronic infections have elevated levels of checkpoint receptors (e.g., programed cell death 1, PD1) on T cells. Monoclonal antibody (mAb)-based inhibitors to checkpo
Externí odkaz:
https://doaj.org/article/d51909df7cf2497487e3e120d0b39991
Autor:
Chun-Shiang Chung, Amy R. Noe, Gabriel M. Gutierrez, Genevieve Weir, Charles C. Reed, Kenneth D. Tucker, Marianne M. Stanford, Alecia MacKay, Timothy W. Phares, Rajkannan Rajagopalan, Cecille D. Browne, Alfred Ayala, Jing Huang, Moriya Tsuji, James Pannucci, Vinayaka Kotraiah, Marc Mansour, Jayne M. Christen
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Many pathogens use the same immune evasion mechanisms as cancer cells. Patients with chronic infections have elevated levels of checkpoint receptors (e.g., programed cell death 1, PD1) on T cells. Monoclonal antibody (mAb)-based inhibitors to checkpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ed85e894b3600426584c69d867a26d
https://pubmed.ncbi.nlm.nih.gov/32210956
https://pubmed.ncbi.nlm.nih.gov/32210956
Publikováno v:
Protein Science. 15:2749-2760
Six alpha-defensins have been found in humans. These small arginine-rich peptides play important roles in various processes related to host defense, being the effectors and regulators of innate immunity as well as enhancers of adoptive immune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b806758a38cc311553abb7c2b7ba7d9
https://doi.org/10.1110/ps.062336606
https://doi.org/10.1110/ps.062336606
Autor:
David M. Hoover, De Yang, Joost J. Oppenheim, Cyril Boulègue, Wuyuan Lu, Jacek Lubkowski, Kenneth D. Tucker
Publikováno v:
Journal of Biological Chemistry. 277:37647-37654
Human macrophage inflammatory protein-3alpha (MIP-3alpha; CCL20) is a CC-type chemokine that binds to and activates CC chemokine receptor-6 (CCR6). Although MIP-3alpha does not share the binding site of CCR6 with any other chemokine, human beta-defen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76dc5bdd5b0fa80576036ea6ec3cadf6
https://doi.org/10.1074/jbc.m203907200
https://doi.org/10.1074/jbc.m203907200
LasR, a Transcriptional Activator of Pseudomonas aeruginosa Virulence Genes, Functions as a Multimer
Publikováno v:
Journal of Bacteriology. 184:4912-4919
The Pseudomonas aeruginosa LasR protein functions in concert with N -3-oxo-dodecanoyl- l -homoserine lactone (3O-C 12 -HSL) to coordinate the expression of target genes, including many genes that encode virulence factors, with cell density. We used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596583359047e7d68973140bbe04c251
https://doi.org/10.1128/jb.184.17.4912-4919.2002
https://doi.org/10.1128/jb.184.17.4912-4919.2002
Autor:
Humberto A. Rossi, Pace John L, Richard I. Walker, Kenneth D. Tucker, Vito M. Esposito, Steve M. Frey
Publikováno v:
Vaccine. 16:1563-1574
Inactivated bacterial whole-cell vaccines have been the most widely studied prophylactic treatment for infectious diseases. They offer an economical, and potentially safe, effective means of preventing disease. The disadvantages of these vaccines hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3c013b13a1412cf45067f119fa8b3a
https://doi.org/10.1016/s0264-410x(98)00046-2
https://doi.org/10.1016/s0264-410x(98)00046-2
Autor:
Thomas G. McCloud, John H. Cardellina, Kenneth D. Tucker, Tamara L. Meragelman, Robert H. Shoemaker
Publikováno v:
Journal of Natural Products. 68:1790-1792
A new isoflavan, (3R)-6,2'-dihydroxy-7-methoxy-4',5'-methylenedioxyisoflavan, hildegardiol (1), and two known flavonoids, 2-hydroxymaackiain (2) and farrerol (3), were isolated from the antifungal root extract of Hildegardia barteri. The pterocarpan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb00787550b31898aa603bbac207d33
https://doi.org/10.1021/np0503000
https://doi.org/10.1021/np0503000