Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kenneth D. Lanclos"'
Publikováno v:
American Journal of Hematology. 65:14-24
A 40-bp DNA, consisting of seven tandem GATA repeats, is located near the HS5 site in the 5′ boundary area of the locus control region (LCR) of human β-globin gene. This (GATA)7 motif, named 5a, exhibits silencer activity in erythroid cells. In tr
Autor:
David F. Scott, Kenneth D. Lanclos, Amanda D. Miller, Donald M. Maxwell, John J. Schlager, Terry L. Chacko
Publikováno v:
Protein Expression and Purification. 17:16-25
Serine-dependent carboxylesterases (EC 3.1.1.1) are found in a variety of tissues with high activity detected in the liver. Carboxylesterases (CaE) hydrolyze aliphatic and aromatic esters, and aromatic amides, and play an important role in the detoxi
Publikováno v:
American Journal of Hematology. 59:51-56
Beta(s)-chromosome haplotypes are peculiar to specific regions of Africa and Asia and are associated with the occurrence of different fetal hemoglobin (Hb) levels in sickle cell patients. Among these haplotypes, beta(s)-chromosomes found in the Seneg
Publikováno v:
Biology of Reproduction. 55:782-788
Mature (60-65 days old) male Sprague-Dawley rats received a single i.p. injection of ethane dimethane sulfonate (EDS, 100 mg/kg BW) and were killed at different times from Days 2 to 60 posttreatment. Bands of cells enriched in precursor Leydig cells
Publikováno v:
American Journal of Hematology. 51:12-18
There are five major haplotypes associated with sickle cell anemia (SS). Individuals homozygous for haplotypes 3 (Senegal) and 31 (Saudi Arabian) have high fetal hemoglobin (HbF) levels (15 to 30% of total hemoglobin) whereas individuals homozygous f
Publikováno v:
Adolescent and Pediatric Gynecology. 6:214-219
Study Objective: To determine if the exons encoding the structural protein for gonadotropin-releasing hormone (GnRH) are present in patients with idiopathic hypogonadotropic hypogonadism (IHH), and whether individual exons possess smaller mutations n
Autor:
Lawrence C. Layman, Kenneth D. Lanclos, Leo Plouffe, J. Rogers Byrd, Paul G. McDonough, Sandra P.T. Tho
Publikováno v:
American Journal of Obstetrics and Gynecology. 167:1794-1802
OBJECTIVES: The purpose of our study was to discover whether the testicular determining factor gene SAY (sex-determining region on Y) is present or absent in XX true hermaphrodites and in subjects with gonadal dysgenesis caused by Y aneuploidy. STUDY
Autor:
Lawrence C. Layman, J. T. Wilson, Dorothy J. Roach, Paul G. McDonough, Sarah W. Wall, Kenneth D. Lanclos
Publikováno v:
Fertility and Sterility. 58:914-918
Objective To determine whether restriction fragment length polymorphisms are present using a deoxyribonucleic acid (DNA) probe for human luteinizing hormone β subunit (hLH- β ). If the gene for hLH -β is polymorphic, genetic diagnosis of disorders
Autor:
M. N. Kitundu, Titus H.J. Huisman, Kenneth D. Lanclos, C. Öner, Ferdane Kutlar, A. J. Dimovski, E. Baysal, Ph. Beris
Publikováno v:
American Journal of Hematology. 41:97-101
We have sequenced the 5' hypersensitive-2 (5'HS-2) site of the locus control region (LCR) and the promoters of the two gamma-globin genes located on chromosome 11 of a black patient with mild beta-thalassemia (beta-thal) major due to a homozygosity f
Autor:
Titus H.J. Huisman, C. Altay, A. J. Dimovski, A. Gurgey, C. Öner, Kenneth D. Lanclos, Y.-C. Gu
Publikováno v:
Blood. 79:813-819
We have compared the sequence of the 5′ hypersensitive site-2 (5′-HS-2) of the locus control region (LCR) from a sickle cell anemia (SS) patient homozygous for haplotype 19 and with low levels of fetal hemoglobin (HbF), with the same sequence fro