Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Kenneth D. Beaman"'
Autor:
Katharine G. Wolf, PhD, Emily B. Crawford, BS, Nora M. Wartan, BS, Sylvia K. Schneiderman, MS, Valerie E. Riehl, MS, Svetlana V. Dambaeva, PhD, Kenneth D. Beaman, PhD
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 336-344 (2022)
Background: Therapeutic angiogenesis aims to induce new blood vessel growth in ischemic tissues; however, previous clinical trials have had limited success. Studies of uterine angiogenesis revealed a specialized subset of natural killer (NK) cells, c
Externí odkaz:
https://doaj.org/article/52e3829ea7a34f54826315aae3ae65a1
Autor:
Arpita Kulshrestha, Gajendra K. Katara, Safaa A. Ibrahim, Valerie E. Riehl, Sylvia Schneiderman, Mahmood Bilal, Alexandria N. Young, Shayna Levine, Sara Fleetwood, James Dolan, Alice Gilman‐Sachs, Kenneth D. Beaman
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2436-2454 (2020)
Tumor acidity is the key metabolic feature promoting cancer progression and is modulated by pH regulators on a cancer cell's surface that pump out excess protons/lactic acid for cancer cell survival. Neutralizing tumor acidity improves the therapeuti
Externí odkaz:
https://doaj.org/article/a303e506c5224df1b905decf62dbe935
Autor:
Safaa A. Ibrahim, Arpita Kulshrestha, Gajendra K. Katara, Valerie Riehl, Manoranjan Sahoo, Kenneth D. Beaman
Publikováno v:
Molecular Oncology, Vol 14, Iss 3, Pp 590-610 (2020)
Tumors and neutrophils undergo an unexpected interaction, in which products released by tumor cells interact to support neutrophils that in turn support cancer growth, angiogenesis, and metastasis. A key protein that is highly expressed by cancer cel
Externí odkaz:
https://doaj.org/article/f0aeb164dc284c279cd938e1f68ba20c
Autor:
Gajendra K. Katara, Arpita Kulshrestha, Sylvia Schneiderman, Valerie Riehl, Safaa Ibrahim, Kenneth D. Beaman
Publikováno v:
Molecular Oncology, Vol 14, Iss 1, Pp 211-224 (2020)
Interleukin (IL)‐22 is recognized as a tumor‐supporting cytokine and is implicated in the proliferation of multiple epithelial cancers. In breast cancer, the current knowledge of IL‐22 function is based on cell line models and little is known a
Externí odkaz:
https://doaj.org/article/83b77ee5d302439a85a5fbca6f080293
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract The Vacuolar ATPase (V-ATPase) is a proton pump responsible for controlling the intracellular and extracellular pH of cells. The structure of V-ATPase has been highly conserved among all eukaryotic cells and is involved in diverse functions
Externí odkaz:
https://doaj.org/article/1945e666289249ae9c071d02e31f4f64
Autor:
Gajendra K. Katara, Arpita Kulshrestha, Liqun Mao, Xin Wang, Manoranjan Sahoo, Safaa Ibrahim, Sahithi Pamarthy, Kimiko Suzue, Gajendra S. Shekhawat, Alice Gilman‐Sachs, Kenneth D. Beaman
Publikováno v:
Molecular Oncology, Vol 12, Iss 2, Pp 208-223 (2018)
Extracellular matrix (ECM) critically impacts tumor progression and is influenced by both cancer and host tissue cells. While our understanding of cancer cell ECM remodeling is widespread, the importance of host tissue ECM, which provides initial con
Externí odkaz:
https://doaj.org/article/2fdedb0d0eda42da86f73dcf151f541e
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nuc
Externí odkaz:
https://doaj.org/article/80c1e35c8d404cf1bc2c92f509ad31c5
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Iodine is an essential element required for the function of all organ systems. Although the importance of iodine in thyroid hormone synthesis and reproduction is well known, its direct effects on the immune system are elusive. Human leukocytes expres
Externí odkaz:
https://doaj.org/article/fc330d768ad6401a968fc3d30dfa964b
Autor:
Renukadevi Patil, Arpita Kulshrestha, Anjali Tikoo, Sara Fleetwood, Gajendra Katara, Bala Kolli, William Seibel, Alice Gilman-Sachs, Shivaputra A. Patil, Kenneth D. Beaman
Publikováno v:
Molecules, Vol 22, Iss 9, p 1559 (2017)
The vacuolar (H+)-ATPases (V-ATPases) are a family of ATP-driven proton pumps and they have been associated with cancer invasion, metastasis, and drug resistance. Despite the clear involvement of V-ATPases in cancer, the therapeutic use of V-ATPase-t
Externí odkaz:
https://doaj.org/article/5d7b76bddab94dc49d20acdc1dd62c09
Autor:
Alfredo Germain, Svetlana Dambaeva, Kenneth D. Beaman, Sylvia Schneiderman, Emilio Fernandez, Joanne Kwak-Kim, Mahmood Bilal, Carolyn Coulam
Publikováno v:
F&S Reports
F&S Reports, Vol 2, Iss 1, Pp 95-103 (2021)
F&S Reports, Vol 2, Iss 1, Pp 95-103 (2021)
Objective: To study decidualization-associated endometrial factors. Design: Retrospective cohort study to compare endometrial gene expression patterns in women experiencing reproductive failure including recurrent pregnancy loss or unexplained infert