Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kenneth D Swanson"'
Autor:
Lamyaa Shaban, Giang T Nguyen, Benjamin D Mecsas-Faxon, Kenneth D Swanson, Shumin Tan, Joan Mecsas
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008576 (2020)
Yersinia suppress neutrophil responses by using a type 3 secretion system (T3SS) to inject 6-7 Yersinia effector proteins (Yops) effectors into their cytoplasm. YopH is a tyrosine phosphatase that causes dephosphorylation of the adaptor protein SKAP2
Externí odkaz:
https://doaj.org/article/7404841bd58143aaafafe08bb611becc
Autor:
Giang T Nguyen, Lamyaa Shaban, Matthias Mack, Kenneth D Swanson, Stephen C Bunnell, David B Sykes, Joan Mecsas
Publikováno v:
eLife, Vol 9 (2020)
Klebsiella pneumoniae is a respiratory, blood, liver, and bladder pathogen of significant clinical concern. We show that the adaptor protein, SKAP2, is required for protection against K. pneumoniae (ATCC 43816) pulmonary infections. Skap2-/- mice had
Externí odkaz:
https://doaj.org/article/e5b85fc244194d89a9dbc2b9e48796d9
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125269 (2015)
The anti-tumor effects of chemotherapy and radiation are thought to be mediated by triggering G1/S or G2/M cell cycle checkpoints, while spindle poisons, such as paclitaxel, block metaphase exit by initiating the spindle assembly checkpoint. In contr
Externí odkaz:
https://doaj.org/article/98c7936c2fd1456eb2d2445cde733aee
Autor:
Hongyun Zhao, Da Teng, Lifeng Yang, Xincheng Xu, Jiajia Chen, Tengjia Jiang, Austin Y. Feng, Yaqing Zhang, Dennie T. Frederick, Lei Gu, Li Cai, John M. Asara, Marina Pasca di Magliano, Genevieve M. Boland, Keith T. Flaherty, Kenneth D. Swanson, David Liu, Joshua D. Rabinowitz, Bin Zheng
Publikováno v:
Nature Metabolism. 4:1660-1673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0af4ad24f6e8fc4f0a415b21038b64
https://doi.org/10.1038/s42255-022-00676-9
https://doi.org/10.1038/s42255-022-00676-9
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Increased myeloid CD86-expressing APCs following cabozantinib treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ad926119417a8868654ca0bf010af4
https://doi.org/10.1158/2159-8290.22531907.v1
https://doi.org/10.1158/2159-8290.22531907.v1
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Dexamethasone attenuates the tumor clearance elicited by cabozantinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2136b515a9e025b1af27fd880ded3395
https://doi.org/10.1158/2159-8290.22531892.v1
https://doi.org/10.1158/2159-8290.22531892.v1
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Significant Tumor Shrinkage following cabozantinib treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1aadb31a9ecb293cd6a7c51f7421a4
https://doi.org/10.1158/2159-8290.22531919.v1
https://doi.org/10.1158/2159-8290.22531919.v1
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Increased CXCL12 within tumor cells by RNA in situ hybridization following cabozantinib treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6c820b7dc107d7b97c0664ca16f498
https://doi.org/10.1158/2159-8290.22531910.v1
https://doi.org/10.1158/2159-8290.22531910.v1
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Blockade of neutrophil chemotaxis/infiltration rescues cabozantinib-induced tumor regression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2528df0f94914f5d27ffd3a592e09120
https://doi.org/10.1158/2159-8290.22531898
https://doi.org/10.1158/2159-8290.22531898
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Cabozantinib-mediated granulocytic infiltration within tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88176d9196071d8fce62506386e352e
https://doi.org/10.1158/2159-8290.22531913
https://doi.org/10.1158/2159-8290.22531913