Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Kenneth D Aldape"'
Autor:
Razelle Kurzrock, Eytan Ruppin, Raanan Berger, Gal Dinstag, Omer Tirosh, Eyal Schiff, David Kleiner, Kenneth D Aldape, Tuvik Beker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Fibrolamellar carcinoma (FLC) is a rare cancer of the liver that most commonly affects children and young adults. There is no clear standard of care for the disease, whose response to treatment seems to be very different from that of hepatocellular c
Externí odkaz:
https://doaj.org/article/40c953c6090540859441fb58c93e0c58
Autor:
Xiaowei Guan, Jaime Vengoechea, Siyuan Zheng, Andrew E Sloan, Yanwen Chen, Daniel J Brat, Brian Patrick O'Neill, John de Groot, Shlomit Yust-Katz, Wai-Kwan Alfred Yung, Mark L Cohen, Kenneth D Aldape, Steven Rosenfeld, Roeland G W Verhaak, Jill S Barnholtz-Sloan
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91216 (2014)
BackgroundGliomas are the most common primary malignant brain tumors in adults with great heterogeneity in histopathology and clinical course. The intent was to evaluate the relevance of known glioblastoma (GBM) expression and methylation based subty
Externí odkaz:
https://doaj.org/article/11d06f53ffa14d86ae428b8cf35f5a14
Autor:
Frank M. Mezzacappa, Frankie K. Smith, Weiwei Zhang, Andrew Gard, Fatmagul Kusku Cabuk, Ignancio Gonzalez-Gomez, Hector L. Monforte, Jiancong Liang, Omkar Singh, Martha M. Quezado, Kenneth D. Aldape, Murat Gokden, Julia A. Bridge, Jie Chen
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Intracranial mesenchymal tumor (IMT), FET::CREB fusion-positive is a provisional tumor type in the 2021 WHO classification of central nervous system tumors with limited information available. Herein, we describe five new IMT cases from four
Externí odkaz:
https://doaj.org/article/4be89ec877884ba4bbc5044654b11183
Autor:
Pablo Freire, Marco Vilela, Helena Deus, Yong-Wan Kim, Dimpy Koul, Howard Colman, Kenneth D Aldape, Oliver Bogler, W K Alfred Yung, Kevin Coombes, Gordon B Mills, Ana T Vasconcelos, Jonas S Almeida
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e4076 (2008)
The Cancer Genome Atlas project (TCGA) has initiated the analysis of multiple samples of a variety of tumor types, starting with glioblastoma multiforme. The analytical methods encompass genomic and transcriptomic information, as well as demographic
Externí odkaz:
https://doaj.org/article/dd24553a7b6645e19e28510902b7bf56
Autor:
Suganth Suppiah, Sheila Mansouri, Yasin Mamatjan, Jeffrey C. Liu, Minu M. Bhunia, Vikas Patil, Prisni Rath, Bharati Mehani, Pardeep Heir, Severa Bunda, German L. Velez-Reyes, Olivia Singh, Nazanin Ijad, Neda Pirouzmand, Tatyana Dalcourt, Ying Meng, Shirin Karimi, Qingxia Wei, Farshad Nassiri, Trevor J. Pugh, Gary D. Bader, Kenneth D. Aldape, David A. Largaespada, Gelareh Zadeh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Malignant peripheral nerve sheath tumor (MPNST) is a highly aggressive sarcoma, and a lethal neurofibromatosis type 1-related malignancy, with little progress made on treatment strategies. Here, we apply a multiplatform integrated molecular
Externí odkaz:
https://doaj.org/article/e359179956df47019171036b9f6ae239
Publikováno v:
Journal of Neuro-Oncology. 161:373-381
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ae82a357e15321f4adf999c05fad5d8
https://doi.org/10.1007/s11060-022-04228-9
https://doi.org/10.1007/s11060-022-04228-9
Autor:
Ignacio I. Wistuba, Kenneth D. Aldape, Waun Ki Hong, Marileila Varella-Garcia, Ritsuko Komaki, Guosheng Yin, Ximing Tang, Natalie Ozburn, Lei Feng, Carmen Behrens, Menghong Sun
Purpose: To compare the characteristics of deregulation of HER receptors and their ligands between primary tumor and corresponding brain metastases of non–small cell lung carcinoma (NSCLC).Experimental Design: Fifty-five NSCLC primary tumors and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adfb0159d005aea299d0521c2b000ba
https://doi.org/10.1158/1078-0432.c.6518370.v1
https://doi.org/10.1158/1078-0432.c.6518370.v1
Autor:
Ignacio I. Wistuba, Kenneth D. Aldape, Waun Ki Hong, Marileila Varella-Garcia, Ritsuko Komaki, Guosheng Yin, Ximing Tang, Natalie Ozburn, Lei Feng, Carmen Behrens, Menghong Sun
Supplementary Data from HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b06690faf785315f897bdf2f6de1ed4
https://doi.org/10.1158/1078-0432.22441257.v1
https://doi.org/10.1158/1078-0432.22441257.v1
Autor:
Michael A. Davies, Darrin Stuart, Victor G. Prieto, Kenneth D. Aldape, Katherine L. Nathanson, Ju-Seog Lee, Wanleng Deng, Cristiano Goncalves Pereira, Y.N. Vashisht Gopal, Alicia A. Ledoux, Scott Kopetz, Sang-Bae Kim, Bradley Wubbenhorst, Michael T. Tetzlaff, Alexander J. Lazar, Kimberly Aardalen, Nitin Chakravarti, Guo Chen
PDF file - 416KB, Supplementary methods, figures and tables. Fig. S1. Gene expression profiling of patient-matched brain and extracranial metastases. Fig. S2. PTEN gene expression in BM_03 (homozygous copy loss) and EM_03 (one copy loss). Gene expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f432f4429ab16f37004e08625ae4d48
https://doi.org/10.1158/1078-0432.22450670
https://doi.org/10.1158/1078-0432.22450670
Autor:
Michael A. Davies, Darrin Stuart, Victor G. Prieto, Kenneth D. Aldape, Katherine L. Nathanson, Ju-Seog Lee, Wanleng Deng, Cristiano Goncalves Pereira, Y.N. Vashisht Gopal, Alicia A. Ledoux, Scott Kopetz, Sang-Bae Kim, Bradley Wubbenhorst, Michael T. Tetzlaff, Alexander J. Lazar, Kimberly Aardalen, Nitin Chakravarti, Guo Chen
Purpose: An improved understanding of the molecular pathogenesis of brain metastases, one of the most common and devastating complications of advanced melanoma, may identify and prioritize rational therapeutic approaches for this disease. In particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58da3522b4aceaee72b5d4dbb12df40f
https://doi.org/10.1158/1078-0432.c.6521993.v1
https://doi.org/10.1158/1078-0432.c.6521993.v1