Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kenneth D, Swanson"'
Autor:
Sarah C. Tinker, Jessica L. Prince-Guerra, Kelly Vermandere, Jenna Gettings, Cherie Drenzik, Gary Voccio, Tonia Parrott, Jan Drobeniuc, Tonya Hayden, Stephen Briggs, Debbie Heida, Natalie Thornburg, Lisa C. Barrios, John C. Neatherlin, Sabrina Madni, Catherine N. Rasberry, Kenneth D. Swanson, Azaibi Tamin, Jennifer L. Harcourt, Sandra Lester, Lydia Atherton, Margaret A. Honein
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-10 (2022)
Abstract Background The objective of our investigation was to better understand barriers to implementation of self-administered antigen screening testing for SARS-CoV-2 at institutions of higher education (IHE). Methods Using the Quidel QuickVue At-H
Externí odkaz:
https://doaj.org/article/35c98739993343ccb4db12e46992aa08
Autor:
Giacomo Canesin, Linda Feldbrügge, Guangyan Wei, Lubica Janovicova, Monika Janikova, Eva Csizmadia, Juliana Ariffin, Andreas Hedblom, Zachary T. Herbert, Simon C. Robson, Peter Celec, Kenneth D. Swanson, Imad Nasser, Yury V. Popov, Barbara Wegiel
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104983- (2022)
Summary: Activation of resident macrophages (Mϕ) and hepatic stellate cells is a key event in chronic liver injury. Mice with heme oxygenase-1 (HO-1; Hmox1)-deficient Mϕ (LysM-Cre:Hmox1flfl) exhibit increased inflammation, periportal ductular react
Externí odkaz:
https://doaj.org/article/f4b11df66d3146fa97c58af8a3bed6d2
Autor:
Lamyaa Shaban, Giang T Nguyen, Benjamin D Mecsas-Faxon, Kenneth D Swanson, Shumin Tan, Joan Mecsas
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008576 (2020)
Yersinia suppress neutrophil responses by using a type 3 secretion system (T3SS) to inject 6-7 Yersinia effector proteins (Yops) effectors into their cytoplasm. YopH is a tyrosine phosphatase that causes dephosphorylation of the adaptor protein SKAP2
Externí odkaz:
https://doaj.org/article/7404841bd58143aaafafe08bb611becc
Autor:
Giang T Nguyen, Lamyaa Shaban, Matthias Mack, Kenneth D Swanson, Stephen C Bunnell, David B Sykes, Joan Mecsas
Publikováno v:
eLife, Vol 9 (2020)
Klebsiella pneumoniae is a respiratory, blood, liver, and bladder pathogen of significant clinical concern. We show that the adaptor protein, SKAP2, is required for protection against K. pneumoniae (ATCC 43816) pulmonary infections. Skap2-/- mice had
Externí odkaz:
https://doaj.org/article/e5b85fc244194d89a9dbc2b9e48796d9
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Heme is one of the most abundant molecules in the body acting as the functional core of hemoglobin/myoglobin involved in the O2/CO2 carrying in the blood and tissues, redox enzymes and cytochromes in mitochondria. However, free heme is toxic and ther
Externí odkaz:
https://doaj.org/article/dacb88eab76b46e6828a7742f6ad3e54
Autor:
Hongyun Zhao, Da Teng, Lifeng Yang, Xincheng Xu, Jiajia Chen, Tengjia Jiang, Austin Y. Feng, Yaqing Zhang, Dennie T. Frederick, Lei Gu, Li Cai, John M. Asara, Marina Pasca di Magliano, Genevieve M. Boland, Keith T. Flaherty, Kenneth D. Swanson, David Liu, Joshua D. Rabinowitz, Bin Zheng
Publikováno v:
Nature Metabolism. 4:1660-1673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0af4ad24f6e8fc4f0a415b21038b64
https://doi.org/10.1038/s42255-022-00676-9
https://doi.org/10.1038/s42255-022-00676-9
Publikováno v:
Cells, Vol 10, Iss 7, p 1801 (2021)
Many anti-cancer therapeutics lead to the release of danger associated pattern molecules (DAMPs) as the result of killing large numbers of both normal and transformed cells as well as lysis of red blood cells (RBC) (hemolysis). Labile heme originatin
Externí odkaz:
https://doaj.org/article/3e9d74f60e3c47f4ba7fadf1f5fa920d
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Increased myeloid CD86-expressing APCs following cabozantinib treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ad926119417a8868654ca0bf010af4
https://doi.org/10.1158/2159-8290.22531907.v1
https://doi.org/10.1158/2159-8290.22531907.v1
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Dexamethasone attenuates the tumor clearance elicited by cabozantinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2136b515a9e025b1af27fd880ded3395
https://doi.org/10.1158/2159-8290.22531892.v1
https://doi.org/10.1158/2159-8290.22531892.v1
Autor:
Lewis C. Cantley, Steven P. Balk, Sabina Signoretti, Jeffrey M. Karp, Huihui Ye, David E. Avigan, Jacalyn M. Rosenblatt, Pier Paolo Pandolfi, Kathleen Kelly, John G. Clohessy, Elena Levantini, Yugang Wang, Todd M. Morgan, Joshua J. Timmons, Laleh Montaser, John M. Asara, Thomas B. Thornley, Jesse Novak, Olivier Elemento, Lily C. Wang, Athalia R. Pyzer, Brian M. Olson, Katja Helenius, Marina P. Gehring, Natalie Landon-Brace, Aniruddh Solanki, Eva Csizmadia, Kenneth D. Swanson, Akash Patnaik
Significant Tumor Shrinkage following cabozantinib treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1aadb31a9ecb293cd6a7c51f7421a4
https://doi.org/10.1158/2159-8290.22531919.v1
https://doi.org/10.1158/2159-8290.22531919.v1