Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kenneth Carl Anderson"'
Autor:
Avishay Edri, Nimrod Ben-Haim, Astar Hailu, Nurit Brycman, Orit Berhani-Zipori, Julia Rifman, Sherri Cohen, Dima Yackoubov, Michael Rosenberg, Ronit Simantov, Hideshima Teru, Keiji Kurata, Kenneth Carl Anderson, Ayal Hendel, Aviad Pato, Yona Geffen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17231 (2023)
Natural killer (NK) cells are a vital component of cancer immune surveillance. They provide a rapid and potent immune response, including direct cytotoxicity and mobilization of the immune system, without the need for antigen processing and presentat
Externí odkaz:
https://doaj.org/article/6dcec55945c5489bbb15cecb993c6b33
Autor:
Marcello Turi, Anjana Anilkumar Sithara, Lucie Hofmanová, David Žihala, Dhwani Radhakrishnan, Alexander Vdovin, Sofija Knápková, Tereza Ševčíková, Zuzana Chyra, Tomáš Jelínek, Michal Šimíček, Annamaria Gullà, Kenneth Carl Anderson, Roman Hájek, Matouš Hrdinka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5623 (2023)
During innate immune responses, myeloid differentiation primary response 88 (MyD88) functions as a critical signaling adaptor protein integrating stimuli from toll-like receptors (TLR) and the interleukin-1 receptor (IL-1R) family and translates them
Externí odkaz:
https://doaj.org/article/bbd36fdd99094097a0e1788301336f89
Autor:
Megan Johnstone, Delaney Vinaixa, Marcello Turi, Eugenio Morelli, Kenneth Carl Anderson, Annamaria Gulla
Publikováno v:
Cells, Vol 11, Iss 16, p 2519 (2022)
Immunological tolerance of myeloma cells represents a critical obstacle in achieving long-term disease-free survival for multiple myeloma (MM) patients. Over the past two decades, remarkable preclinical efforts to understand MM biology have led to th
Externí odkaz:
https://doaj.org/article/42933febcd1543988f843d167ee469ae
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Multiple myeloma (MM) is an incurable malignancy of plasma cells that grow within a permissive bone marrow microenvironment (BMM). The bone marrow milieu supports the malignant transformation both by promoting uncontrolled proliferation and resistanc
Externí odkaz:
https://doaj.org/article/fd3c2507208c4198a9919bbd6a81dd47
Publikováno v:
Cancer Research. 82:5352-5352
Daratumumab (Dara) is the first-in-class monoclonal antibody targeting CD38 which triggers both direct and immune mediated cytotoxicity in preclinical in vitro and in vivo models of multiple myeloma (MM) in the bone marrow (BM) milieu. Importantly, D
Autor:
Maria Moscvin, Peter Gregor Czarnecki, Tianzeng Chen, Annamaria Gullá, Kenneth Carl Anderson, Giada Bianchi
Publikováno v:
Cancer Research. 82:141-141
AL amyloidosis (AL) is an incurable plasma cell disorder. The solely pathogenic mechanism in AL is deposition of immunoglobulin free light chains (FLC) organized in fibrils in target organs. Surprisingly, therapeutic strategies directly targeting FLC
Autor:
Paul G. Richardson, Susanna J. Jacobus, Edie Weller, Hani Hassoun, Sagar Lonial, Noopur S. Raje, Eva Medvedova, Philip L. McCarthy, Edward N. Libby, Peter M. Voorhees, Robert Z. Orlowski, Larry D. Anderson, David D. Hurd, Marcelo C. Pasquini, Kelly Masone, Philippe Moreau, Herve Avet-Loiseau, Michel Attal, Kenneth Carl Anderson, Nikhil C. Munshi
Publikováno v:
Journal of Clinical Oncology. 40:LBA4-LBA4
LBA4 Background: Optimal use of triplet/quadruplet induction, ASCT, and R-based maintenance in patients (pts) with NDMM who are eligible for transplant continues to evolve. The IFM 2009 trial, which used R maintenance for 1 year (y), showed progressi
Autor:
Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Nikhil C. Munshi, Shin Kaneko, Jerome Ritz, Kenneth Carl Anderson
Publikováno v:
Journal of Clinical Oncology. 40:2542-2542
2542 Background: A strategy for reversal of T cell exhaustion is reprograming of antigen-specific CTL to early lineage memory T cells with selective anti-tumor activities. To accomplish this goal, we epigenetically reprogrammed BCMA-specific CD8+ CTL