Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kenneth C. Swanson"'
Autor:
Michelle E. Savedra, James D. Hoyer, Jennifer L. Oliveira, Phuong L. Nguyen, Jessica Szuberski, Camila Dergam-Larson, Aruna Rangan, Tavanna R. Porter, Min Shi, Kenneth C. Swanson, Ronald S. Go, Sarah E. Brunker
Publikováno v:
International journal of laboratory hematologyREFERENCES. 43(4)
Introduction Methemoglobin (MetHb) and sulfhemoglobin (SHb) measurements are useful in the evaluation of cyanosis. When one or both values are elevated, additional analysis is important to establish the etiology of the disorder. Methemoglobinemia occ
Autor:
Mrinal M. Patnaik, Kenneth C. Swanson, Ayalew Tefferi, James D. Hoyer, Jennifer L. Oliveira, Stefan K.G. Grebe, Molly S. Hein, Michelle E. Savedra, Animesh Pardanani, Tavanna R. Porter, David S. Viswanatha, Lori Frederick, Lea M. Coon
Publikováno v:
American journal of hematology.
Hereditary erythrocytosis is associated with high oxygen affinity hemoglobin variants (HOAs), 2,3-bisphosphoglycerate deficiency and abnormalities in EPOR and the oxygen-sensing pathway proteins PHD, HIF2α, and VHL. Our laboratory has 40 years of ex
Autor:
Tyler J. Winkler, Rachel LaCount, D. Brian Dawson, Michael W. Kent, Xiayuan Liang, Jennifer L. Oliveira, Kenneth C. Swanson, James D. Hoyer, Christopher C. Silliman, Michelle L. Kluge, Charles W. Breaux
Publikováno v:
Hemoglobin. 38:8-12
Hyperunstable hemoglobinopathy (HUH) [dominantly inherited β-thalassemia (β-thal)] is a relatively rare form of congenital hemolytic anemia in which mutations occur in the genes encoding for α and β chains, or both chains of the hemoglobin (Hb) m
Autor:
Lauren Lubrano, D. Brian Dawson, Jennifer L. Oliveira, Kenneth C. Swanson, Gerald Sandler, Michael J. Donnelly, James D. Hoyer
Publikováno v:
Hemoglobin. 38:137-141
Hb Memphis [α23(B4)Glu→Gln; HBA2: c.70G C (or HBA1)] is a stable hemoglobin (Hb) variant caused by a substitution of glutamine for glutamic acid at residue 23 of the α2- or α1-globin chain. Heterozygous Hb Memphis has no known clinical or hemato
Autor:
Lea M. Coon, Anderson B. Collier, Philip M. Monteleone, Jennifer L. Oliveira, Samuel Umaru, Kenneth C. Swanson, James D. Hoyer
Publikováno v:
Hemoglobin. 40(2)
Hemoglobin (Hb) variants may be associated with low oxygen saturation and exacerbated episodes of anemia from common stressors such as viral infections. These attributes frequently cause increased clinical concern and unnecessary and expensive testin
Publikováno v:
Hemoglobin. 38(4)
A novel β(0)-thalassemia (β-thal) frameshift mutation, HBB: c.209delG; p.Gly70Valfs*20, is described in a 21-year-old African American female with β-thalassemia major (β-TM) due to compound heterozygosity for the β(0)-thal mutation HBB: c.92+2T>
Publikováno v:
Journal of Pediatric Hematology/Oncology. 27:618-620
Summary: Hemoglobin Abruzzo is a stable hemoglobin variant with increased oxygen affinity, clinically causing compensatory erythrocytosis in affected patients. Heterozygosity of this variant with or without β-thalassemia has been previously describe
Autor:
Rendell W. Ashton, Rachel M. Taliercio, Kenneth C. Swanson, James D. Hoyer, Patricia Wendt, Leonard J. Horwitz, Jennifer L. Oliveira
Publikováno v:
Hemoglobin. 37(4)
A previously unreported β chain hemoglobin (Hb) variant, Hb Grove City [β38(C4)Thr→Ser, ACC>AGC; HBB: c.116C>G], was discovered in a woman who presented with hypoxia and mild anemia. Her young daughter also tested positive for the variant and dis
Autor:
Patrick A. Lundquist, Kenneth C. Swanson, Brian Dawson, Joella A Yungerberg, Ronald S. Go, Molly S. Hein, James D. Hoyer, Lea M. Coon, Dragan Jevremovic, Jennifer L. Oliveira
Publikováno v:
Blood. 126:3374-3374
Background: Large deletions involving the beta globin complex are relatively rare. They can be categorized generally into five groups by deletion size and/or location: 1) beta zero thalassemia (BZT); 2) delta beta thalassemia (DBT); 3) hereditary per
Autor:
Kenneth C. Swanson, Patrick A. Lundquist, Molly S. Hein, James D. Hoyer, Andre M. Oliveira, Brian Dawson, Joella A Yungerberg, Jennifer L. Oliveira, Lea M. Coon, Dragan Jevremovic
Publikováno v:
Blood. 126:3372-3372
Background: The control of hemoglobin F (Hb F) expression has proven an elusive puzzle with several postulated but not mutually exclusive hypotheses. A silencing mechanism hypothesis, which predicts the existence of a regulatory element that suppress