Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kenneth C. Lewis"'
Publikováno v:
Toxicological Sciences
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human adrenocortical carcinoma cells was used to evaluate the ef
Autor:
Gina A. Simone, Andrew Lewandowski, Katherine Y. Berezny, Amy Delinsky, Barrie Harper, Ian M. Paul, T. Bratton, Zhaoxia Ren, Edmund V. Capparelli, B. Poindexter, Andrew M. Atz, Kanecia O. Zimmerman, Kelly C. Wade, J. Sullivan, Thomas J. Walsh, Chiara Melloni, Alice Pagan, T. M. O'Shea, H. Al Nasiri, Daniel Gonzalez, A. Lewandowski, K. Tsilou, David A. Siegel, Gregory L. Kearns, Daniel K. Benjamin, Brenda B. Poindexter, L. Smiley, A. Muelenaer, P B Smith, L. Fern, Michael Cohen-Wolkowiez, Paula Delmore, Janice E. Sullivan, Ravinder Anand, J. N. van den Anker, Donna Cannonier, Anne Zajicek, Ram Yogev, Perdita Taylor-Zapata, R. Yogev, M M Laughon, Kenneth C. Lewis, Susan R. Mendley, B. Harper
Publikováno v:
Bioanalysis. 7:1137-1149
Background: Trimethoprim-sulfamethoxazole (TMP-SMX) is an antimicrobial drug combination commonly prescribed in children and adults. The study objectives were to validate and apply an HPLC–MS/MS method to quantify TMP-SMX in dried plasma spots (DPS
Autor:
Michael Cohen-Wolkowiez, Barrie Harper, Chiara Melloni, Kevin M. Watt, Janice E. Sullivan, Paula Delmore, Kenneth C. Lewis, Julie Autmizguine, Edmund V. Capparelli, Susan R. Mendley, Andrew Lewandowski, Brenda B. Poindexter, Daniel K. Benjamin, Ram Yogev, Daniel Gonzalez
Publikováno v:
Clinical Pharmacology & Therapeutics. 96:429-437
Clindamycin is commonly prescribed to treat children with skin and skin structure infections (including those caused by community-acquired methicillin-resistant Staphylococcus aureus [CA-MRSA]), yet little is known about the pharmacokinetics (PK) acr
Autor:
Kenneth C. Lewis, Jill Schreiwer, James R. Beadle, Jacqueline C. Ruiz, R. Mark L. Buller, Karl Y. Hostetler, Kathy A. Keith, Mark N. Prichard
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2950-2958
Alkoxyalkyl esters of cidofovir (CDV) are orally active agents which inhibit the replication of a variety of double stranded DNA (dsDNA) viruses including variola, vaccinia, ectromelia, herpes simplex virus, cytomegalovirus, adenovirus and others. On
Autor:
Joseph D Simpkins, Kenneth C Lewis
Publikováno v:
ASSAY and Drug Development Technologies. 5:695-702
Publikováno v:
American Journal of Obstetrics and Gynecology. 212:S379-S380
Publikováno v:
American Journal of Obstetrics and Gynecology. 212:S89-S90
Publikováno v:
Journal of Microcolumn Separations. 10:467-471
Publikováno v:
Journal of the American Society for Mass Spectrometry. 8:495-500
Peptide standards and tryptic digests of ribonuclease B are separated by comprehensive two-dimensional reversed phase liquid chromatography (RPLC) and capillary zone electrophoresis (CZE) and detected on-line by electrospray mass spectrometry. The RP
Publikováno v:
Analytical Chemistry. 69:983-989
The use of extremely high pressures in liquid chromatography can improve the efficiency and reduce analysis time for columns packed with small particles. In this work, fused-silica capillaries with inner diameters of 30 microns are slurry packed with