Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Kenneth B.M. Reid"'
Autor:
Trevor J. Greenhough, I. Burns, Alpana Prasad, Kenneth B.M. Reid, Annette K. Shrive, Alister W. Dodds, Janet M. Paterson, Amy J. Shaw
Bovine conglutinin is an immune protein that is involved in host resistance to microbes and parasites and interacts with complement component iC3b, agglutinates erythrocytes, and neutralizes influenza A virus. Here, we determined the high-resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdeead363810eb6caccef982af4ee4d
https://eprints.keele.ac.uk/7142/1/zbc999191415p.pdf
https://eprints.keele.ac.uk/7142/1/zbc999191415p.pdf
Autor:
Robert B. Sim, Uday Kishore, Patrick Waters, Trevor J. Greenhough, Gérard J. Arlaud, Christine Gaboriaud, Kenneth B.M. Reid, Annette K. Shrive
C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of ligands via its g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b704a46df422a71d63b1d612b899ee93
https://doi.org/10.1016/j.it.2004.08.006
https://doi.org/10.1016/j.it.2004.08.006
Properdin is a regulatory glycoprotein of the alternative pathway of the complement system of immune defense. It is responsible for the stabilization of the C3 convertase complex formed between C3b and the Bb fragment of factor B. Neutron and X-ray s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a64e91377c99cb4b3f4557eb80c7f4
https://doi.org/10.1021/bi00246a018
https://doi.org/10.1021/bi00246a018
Autor:
Howard Clark, Derek W. Hood, Trevor J. Greenhough, J. Paul Townsend, Amy J. Shaw, E. Richard Moxon, Mary E. Deadman, Kenneth B.M. Reid, Abdul Ahmed, Rose-Marie Mackay, Annette K. Shrive, Jens Madsen
The carbohydrate recognition domains (CRDs) of lung collectin surfactant protein D (SP-D) recognize sugar patterns on the surface of lung pathogens and promote phagocytosis. Using Haemophilus influenzae Eagan strains expressing well-characterized lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257048ee3de8cc15ecabd76c4c7ec482
https://eprints.keele.ac.uk/1535/1/as_infec_immun_2016.pdf
https://eprints.keele.ac.uk/1535/1/as_infec_immun_2016.pdf
Autor:
Eamon Patrick McGreal, Annelyse Duvoix, Kenneth B.M. Reid, Neil G Henderson, Howard Clark, Rose-Marie Mackay, Anthony D. Postle
Publikováno v:
Immunobiology. 216:72-79
Surfactant protein D (SP-D) plays an important role in lung host defence. SP-D levels have been shown to be depleted in cystic fibrosis (CF) patients. A recombinant fragment of the human SP-D (rfhSP-D) which consist of a hydrophobic neck and a CRD ha
Autor:
Uday Kishore, Samuel Hawgood, Mamta Singh, Annapurna Nayak, Kenneth B.M. Reid, Taruna Madan, P. Usha Sarma, Howard Clark
Publikováno v:
Molecular Immunology. 47:1923-1930
Pulmonary surfactant proteins, SP-A and SP-D, are carbohydrate pattern recognition molecules of innate immunity, which significantly enhance phagocytosis and killing of Aspergillus fumigatus, a pathogenic fungus, by neutrophils and macrophages. The p
Autor:
Umakhanth Venkatraman Girija, Robert B. Sim, Wilhelm J. Schwaeble, Alister W. Dodds, Júlia Tóth, Anthony H. Keeble, Christopher M. Furze, Anna Phillips, Russell Wallis, Eleni Pala, Ralf Schmid, Kenneth B.M. Reid
Publikováno v:
The Journal of Immunology. 182:7708-7717
The classical and lectin pathways of complement activation neutralize pathogens and stimulate key immunological processes. Both pathways are initiated by collagen-containing, soluble pattern recognition molecules associated with specific serine prote
Autor:
N Y Mao, Zuo Li Xia, Kenneth B.M. Reid, P. G. De Groot, W B Xu, Uffe Holmskov, Shao Dong Pan, Zhihua Liu, Ya Ping Wu, Grith Lykke Sørensen, Ran Wei, F S Zhang, Ji Ju Han, Biao Chen
Publikováno v:
Scandinavian Journal of Immunology
Wu, Y P, Liu, Z H, Wei, R, Pan, S D, Mao, N Y, Chen, B, Han, J J, Zhang, F S, Holmskov, U, Xia, Z L, de Groot, P G, Reid, K B M, Xu, W B & Sørensen, G L 2009, ' Elevated plasma surfactant protein D (SP-D) levels and a direct correlation with anti-severe acute respiratory syndrome coronavirus-specific IgG antibody in SARS patients ', Scandinavian Journal of Immunology, vol. 69, no. 6, pp. 508-15 . https://doi.org/10.1111/j.1365-3083.2009.02245.x
Wu, Y P, Liu, Z H, Wei, R, Pan, S D, Mao, N Y, Chen, B, Han, J J, Zhang, F S, Holmskov, U, Xia, Z L, de Groot, P G, Reid, K B M, Xu, W B & Sørensen, G L 2009, ' Elevated plasma surfactant protein D (SP-D) levels and a direct correlation with anti-severe acute respiratory syndrome coronavirus-specific IgG antibody in SARS patients ', Scandinavian Journal of Immunology, vol. 69, no. 6, pp. 508-15 . https://doi.org/10.1111/j.1365-3083.2009.02245.x
Pulmonary SP‐D is a defence lectin promoting clearance of viral infections. SP‐D is recognized to bind the S protein of SARS‐CoV and enhance phagocytosis. Moreover, systemic SP‐D is widely used as a biomarker of alveolar integrity. We investi
Autor:
Samuel Hawgood, Kenneth B.M. Reid, Paul A. Townsend, Joachim Richter, Katharina Wucherpfennig, Lars Knudsen, Christian Mühlfeld, Rose-Marie Mackay, Matthias Ochs, Howard Clark
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 292:183-189
Emphysema-like pathology is a characteristic feature of surfactant protein D (SP-D) knock-out mice. Treatment with a recombinant fragment of human SP-D consisting of a short collagen-like stalk (but not the entire collagen-like domain of native SP-D)