Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kenneth B. Larson"'
Publikováno v:
Annals of Neurology. 38:599-609
Attempts to measure blood-to-brain glucose transport and cerebral glucose metabolism with 11 C-glucose have been hampered by methods that require jugular venous sampling or do not adequately account for the efflux of labeled metabolites from the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f4908552b142a975c20dc141982e5a
https://doi.org/10.1002/ana.410380408
https://doi.org/10.1002/ana.410380408
Autor:
Kenneth B. Larson, John M. Ollinger, Kenneth Zierler, Joel S. Perlmutter, William H. Perman, Mokhtar H. Gado
Publikováno v:
Journal of Theoretical Biology. 170:1-14
Measurement of regional cerebral blood flow in vivo has proved useful in the study of normal and diseased states in the brain. This circumstance has led to a variety of techniques for its quantitative determination and has continued to motivate the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee40bcb0e0c05752fdeacdd453d86276
https://doi.org/10.1006/jtbi.1994.1164
https://doi.org/10.1006/jtbi.1994.1164
Autor:
Ronald G. Tilton, Joseph R. Williamson, John A. Watts, S P Sutera, Marishawn P. Land, Kenneth B. Larson
Publikováno v:
Journal of Molecular and Cellular Cardiology. 23:861-872
Effects of a low dose (5 nM) of nisoldipine on vascular and ventricular function were assessed in isolated rabbit hearts during 2 h of reperfusion after 40 min of global, zero-flow ischemia. External detection of bolus injections of 125I-BSA and pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464f1a890717b685f5debcf0ea972448
https://doi.org/10.1016/0022-2828(91)90219-c
https://doi.org/10.1016/0022-2828(91)90219-c
Autor:
Ann Mary MacLeod, Joanne Markham, Kenneth B. Larson, Marcus E. Raichle, Mark A. Mintun, Robert P. Quarles
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 13(5)
To further our understanding of the best way to measure regional CBF with positron emission tomography (PET), we directly compared two candidate tracers ([15O]water and [11C]butanol, administered intravenously) and two popular implementations of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6001feb653c6556dc95e19dcb6ebfde0
https://pubmed.ncbi.nlm.nih.gov/8360280
https://pubmed.ncbi.nlm.nih.gov/8360280
Publikováno v:
Magnetic resonance imaging. 11(3)
Recently we developed the simultaneous dual FLASH (SDFLASH) pulse sequence that simultaneously obtains sequential images from the brain and the internal-carotid arteries in the neck with 1-sec temporal resolution using a standard MR scanner. The high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc33765252ca663f2ad499a94acabf1
https://pubmed.ncbi.nlm.nih.gov/8505869
https://pubmed.ncbi.nlm.nih.gov/8505869
Publikováno v:
Magnetic resonance in medicine. 28(1)
Regional cerebral blood flow (rCBF) provides important information about local neuronal functional and cerebrovascular status. Determination of rCBF requires sequential measurements of tracer concentration in arterial blood and brain tissue unless th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a491472ba3dcf03ef4920bbe19285a94
https://pubmed.ncbi.nlm.nih.gov/1435223
https://pubmed.ncbi.nlm.nih.gov/1435223
Publikováno v:
Circulation Research. 52:210-225
To define relationships better between the duration of severe ischemia and microvascular functional integrity with an approach potentially applicable to studies in vivo, the effects of 30 and 60 minutes of global, no-flow ischemia on the coronary vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34d00765039acbb73963ac53a52f381
https://doi.org/10.1161/01.res.52.2.210
https://doi.org/10.1161/01.res.52.2.210
Publikováno v:
European Neurology. 20:207-214
This paper introduces a model for the computation of the regional cerebral metabolic rate of oxygen from the data of cerebral regional radioactivity collected after inhalation of 15O2. A method was devised for the differential determination of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::254c736f5430a3851db533875a18ef6e
https://doi.org/10.1159/000115235
https://doi.org/10.1159/000115235
Publikováno v:
Journal of Electron Microscopy Technique. 2:611-636
A new method for analysis of electron microscope autoradiographs is described which is based on the maximum-likelihood method of statistics for estimating the intensities of radioactivity in organelle structures. We adopted a Poisson statistical mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67915478c45f8bc1bd8955e72bc93f6a
https://doi.org/10.1002/jemt.1060020612
https://doi.org/10.1002/jemt.1060020612
Publikováno v:
Microvascular Research. 36:305-313
Isovolumically beating, isolated hearts from male New Zealand rabbits were perfused retrograde via the aorta at a paced rate of 180 to 200 beats per minute. Perfusions were effected at arterial pressures (AP) ranging from 10 to 80 mm Hg. Perfusions (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28cc271d28f45ce2f1c8fa3ff1db95e
https://doi.org/10.1016/0026-2862(88)90030-1
https://doi.org/10.1016/0026-2862(88)90030-1