Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kenneth B, Walsh"'
Autor:
Haley K. Andersen, Duncan G. Vardakas, Julie A. Lamothe, Tannis E. A. Perault, Kenneth B. Walsh, Robert B. Laprairie
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The type 1 cannabinoid receptor (CB1R) mediates neurotransmitter release and synaptic plasticity in the central nervous system. Endogenous, plant-derived, synthetic cannabinoids bind to CB1R, initiating the inhibitory G-protein (Gi) and the
Externí odkaz:
https://doaj.org/article/d71659cbb0bd4ebfacbd131960cfbc84
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient China and Egypt. While marijuana has recently shown promise in managing chronic pain and nausea, scientific investigation of cannabis has been restricted due its
Externí odkaz:
https://doaj.org/article/6b487f3a30f84fcbbf4cde21f7bdcadb
Autor:
Kenneth B. Walsh, Haley K. Andersen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6115 (2020)
Synthetic cannabinoids (SCs) are a class of new psychoactive substances (NPSs) that exhibit high affinity binding to the cannabinoid CB1 and CB2 receptors and display a pharmacological profile similar to the phytocannabinoid (-)-trans-Δ9-tetrahydroc
Externí odkaz:
https://doaj.org/article/7200d5d149154d9cbe82b0c0e9235dc0
Autor:
Kenneth B. Walsh, Andrea E. Holmes
Publikováno v:
Receptors; Volume 1; Issue 1; Pages: 3-12
(1) Background: In addition to the major phytocannabinoids, trans-Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), the cannabis plant (Cannabis sativa L.) synthesizes over 120 additional cannabinoids that are known as minor cannabinoids. The
Publikováno v:
RSC Advances. 10:37728-37734
A graphene-based ion sensitive field effect transistor (GISFET) has been developed and investigated in terms of its ion sensing performance. The GISFET sensor was found to demonstrate a high detection sensitivity enabling direct measurement of K+ ion
Autor:
Kenneth B. Walsh, Haley K. Andersen
Publikováno v:
Eur J Pharmacol
Recreational use of synthetic cannabinoids (SCs) is associated with desirable euphoric and relaxation effects as well as adverse effects including anxiety, agitation and psychosis. These SC-mediated actions represent a combination of potentiated cann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5d2711ccfd0f086a60e59cb3cb1c16
https://europepmc.org/articles/PMC8374946/
https://europepmc.org/articles/PMC8374946/
Autor:
Haley K. Andersen, Kenneth B. Walsh
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6115, p 6115 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Synthetic cannabinoids (SCs) are a class of new psychoactive substances (NPSs) that exhibit high affinity binding to the cannabinoid CB1 and CB2 receptors and display a pharmacological profile similar to the phytocannabinoid (-)-trans-Δ9-tetrahydroc
Publikováno v:
RSC advances. 10(62)
A graphene-based ion sensitive field effect transistor (GISFET) has been developed and investigated in terms of its ion sensing performance. The GISFET sensor was found to demonstrate a high detection sensitivity enabling direct measurement of K
Autor:
Kenneth B. Walsh
Publikováno v:
SLAS discovery : advancing life sciences RD. 25(5)
K+ channels play a critical role in maintaining the normal electrical activity of excitable cells by setting the cell resting membrane potential and by determining the shape and duration of the action potential. In nonexcitable cells, K+ channels est
Publikováno v:
Sensors and Actuators B: Chemical. 253:759-765
Graphene-based ion sensitive field effect transistors (GISFETs) with high sensitivity and selectivity for K+ ion detection have been demonstrated utilizing valinomycin based ion selective membrane. The performance of the GISFETs for K+ ion detection