Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kenneth Allen Savin"'
Autor:
Kenneth Allen Savin
A nucleophile is an electron donor (has an electron pair available for bonding) that bonds to an atom other than hydrogen. A base is an electron donor that bonds to hydrogen. The transformations that result from the action of bases or nucleophiles ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32058bbeb4d9da13e6a5517d9e1af675
https://doi.org/10.1016/b978-0-12-411475-3.00003-8
https://doi.org/10.1016/b978-0-12-411475-3.00003-8
Autor:
Kenneth Allen Savin
Reductions and oxidations are chemical transformations where electrons have been added or removed from a molecule. In organic chemistry, oxidation or reduction may not actually involve electron transfer, but rather may involve a change in oxidation n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6093ddb2d9549cf886b2aa6bfc252d0
https://doi.org/10.1016/b978-0-12-411475-3.00007-5
https://doi.org/10.1016/b978-0-12-411475-3.00007-5
Autor:
Kenneth Allen Savin
The flow of electrons is fundamental to understanding the mechanism of a chemical transformation. The driving forces and key levers associated with the model we present are described in this chapter. These levers include electron flow and acid/base t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3b1ecfb4b6963465745ec69758e56d
https://doi.org/10.1016/b978-0-12-411475-3.00002-6
https://doi.org/10.1016/b978-0-12-411475-3.00002-6
Autor:
Kenneth Allen Savin
To understand the way atoms bond to one another and then transform into new structures it is important to have a common set of rules and definitions. Herein, we describe key aspects of bonding, equilibrium, and driving forces that influence the struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b4657bec533cde0dd74ea53047e0bd
https://doi.org/10.1016/b978-0-12-411475-3.00001-4
https://doi.org/10.1016/b978-0-12-411475-3.00001-4
Autor:
Kenneth Allen Savin
An organic reaction in which a cyclic transition state leads to a concerted transformation. A majority of these reactions are rearrangements and are consistent to the point of being very predictable using systems that have been developed upon numerou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf1a61a08f49c289aa2c0d413073c3b
https://doi.org/10.1016/b978-0-12-411475-3.00006-3
https://doi.org/10.1016/b978-0-12-411475-3.00006-3
Autor:
Kenneth Allen Savin
Radicals are species that contain one or more unpaired electrons. Although radical species are electron deficient, they are usually uncharged and this imparts properties and chemistries that are significantly different from that seen with cations or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f89b89e81eddc24d8bcf1bed163bfa5
https://doi.org/10.1016/b978-0-12-411475-3.00005-1
https://doi.org/10.1016/b978-0-12-411475-3.00005-1
Autor:
Kenneth Allen Savin
Electrophiles are electron-deficient species that are attracted to an electron-rich center. Electrophiles react by accepting an electron pair in order to form a bond to a nucleophile including the interactions of a proton and a base. Electrophiles ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ed1b5868d49c0eeab9d67e53fae51b7
https://doi.org/10.1016/b978-0-12-411475-3.00004-x
https://doi.org/10.1016/b978-0-12-411475-3.00004-x
Autor:
Jessie L. Bishop, Kenneth Allen Savin, Michael Alan Robertson, Erik James Hembre, Steven James Green, Doug Gernert
Publikováno v:
Molecular diversity. 7(2-4)
Herein we describe the conversion of a known [3+2] cycloaddition reaction between an azide and an acetylene from a thermally promoted reaction to a microwave assisted process. Modification of conditions including concentration, temperature, solvent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd42585c05de5370aaf0f6b3d04877d
https://pubmed.ncbi.nlm.nih.gov/14870847
https://pubmed.ncbi.nlm.nih.gov/14870847
Autor:
Gregory L. Durst, Philip Arthur Hipskind, Daniel H. Robertson, Richard E. Higgs, Michal Vieth, Kenneth Allen Savin, Ian A. Watson, Miles Goodman Siegel
Publikováno v:
Journal of medicinal chemistry. 47(1)
An increasingly competitive pharmaceutical market demands improvement in the efficiency and probability of drug candidate discovery. Usually these new drug candidates are targeted for oral administration, so a detailed understanding of the molecular-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6224109696056f42a4d0f21ba858d6a3
https://pubmed.ncbi.nlm.nih.gov/14695836
https://pubmed.ncbi.nlm.nih.gov/14695836