Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Kenneth A. Rubinson"'
Publikováno v:
Toxins, Vol 13, Iss 12, p 888 (2021)
We are studying the structures of bacterial toxins that form ion channels and enable macromolecule transport across membranes. For example, the crystal structure of the Staphylococcus aureus α-hemolysin (α-HL) channel in its functional state was co
Externí odkaz:
https://doaj.org/article/99cad4b1136f44f9ba4ddaa538ed8e94
Autor:
Curtis W. Meuse, Kenneth A. Rubinson
Publikováno v:
Applied Spectroscopy. 77:27-36
Circular dichroism (CD) measurements help characterize optically active molecules and higher-order biomolecular structures. The harmonization of interlaboratory CD measurements requires minimizing measurement uncertainties and determinate errors. Mos
Publikováno v:
Physical Chemistry Chemical Physics. 22:13479-13488
X-ray and neutron scattering have provided insight into the short range (
Autor:
Kenneth A. Rubinson
Publikováno v:
The Protein Journal. 38:95-119
Proteins are polymers, and yet the language used in describing their thermodynamics and kinetics is most often that of small molecules. Using the terminology and mathematical descriptions of small molecules impedes understanding why proteins have evo
Publikováno v:
Analytical Chemistry. 90:5066-5074
As has long been understood, the noise on a spectrometric signal can be reduced by averaging over time, and the averaged noise is expected to decrease as t1/2, the square root of the data collection time. However, with contemporary capability for fas
Autor:
Kenneth A. Rubinson
Publikováno v:
Analytical Methods. 9:2744-2750
Mixtures of light and heavy water are used in NMR, small-angle neutron scattering (SANS), growth media for producing deuterated biological molecules, and analytical methods such as hydrogen–deuterium exchange (HDX) mass spectrometry. It is common t
Autor:
Antonio Faraone, Kenneth A. Rubinson
Publikováno v:
Physical Chemistry Chemical Physics. 18:12707-12715
X-ray and neutron scattering have been used to provide insight into the structures of ionic solutions for over a century, but the probes have covered distances shorter than 8 Å. For the non-hydrolyzing salt SrI2 in aqueous solution, a locally ordere
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:2364-2374
The solution structure of the full-length DNA helicase minichromosome maintenance protein from Methanothermobacter thermautotrophicus was determined by small-angle neutron scattering (SANS) data together with all-atom molecular modeling. The data wer
Autor:
Kenneth A. Rubinson
Publikováno v:
Journal of Solution Chemistry. 43:453-464
X-ray and neutron scattering have been used to provide insight into the structures of ionic solutions for over a century. Most of the structures discussed in the literature cover distances less than 8 A. Outside that distance, single scattering bands
Heparin is a linear, anionic polysaccharide that is widely used as a clinical anticoagulant. Despite its discovery 100 years ago in 1916, the solution structure of heparin remains unknown. The solution shape of heparin has not previously been examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf29815d0d94d6e21ba24610663c89ef
https://europepmc.org/articles/PMC5033728/
https://europepmc.org/articles/PMC5033728/