Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kenneth A. Jenrow"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
BackgroundPrevious reports have established an association between impaired clearance of macromolecular waste from the brain parenchyma and a variety of brain insults for which chronic neuroinflammation is a common pathological feature. Here we inves
Externí odkaz:
https://doaj.org/article/a953fd845654438da65fa43c92f107d4
Autor:
Stephen L. Brown, Andrew Kolozsvary, Derek M. Isrow, Karine Al Feghali, Karen Lapanowski, Kenneth A. Jenrow, Jae Ho Kim
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells and increases in toxicity when used in combination with radiation. In addition to various molecular and metabolic mechanisms that have been previously pro
Externí odkaz:
https://doaj.org/article/c7facccff35c4782aa3a1d340abd9356
Autor:
William E. Medendorp, Eric D. Petersen, Akash Pal, Lina-Marie Wagner, Alexzander R. Myers, Ute Hochgeschwender, Kenneth A. Jenrow
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Mice socially isolated during adolescence exhibit behaviors of anxiety, depression and impaired social interaction. Although these behaviors are well documented, very little is known about the associated neurobiological changes that accompany these b
Externí odkaz:
https://doaj.org/article/c9964b2c0f28438c891ca4dd034bc26e
Publikováno v:
Radiation Oncology Journal
Successful anticancer strategies require a differential response between tumor and normal tissue (i.e., a therapeutic ratio). In fact, improving the effectiveness of a cancer therapeutic is of no clinical value in the absence of a significant increas
Autor:
Jae Ho Kim, Karine A Al Feghali, Derek Isrow, Kenneth A. Jenrow, Karen Lapanowski, Andrew Kolozsvary, Stephen L. Brown
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology
Frontiers in Oncology
Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells and increases in toxicity when used in combination with radiation. In addition to various molecular and metabolic mechanisms that have been previously pro
Autor:
Satish Krishnamurthy, E. Mark Haacke, Jie Li, Kenneth A. Jenrow, Yimin Shen, Thomas M. Duncan
Publikováno v:
Brain research. 1678
Publikováno v:
International Journal of Radiation Biology. 89:311-318
To summarize current knowledge regarding mechanisms of radiation-induced skin injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity modulated radiation therapy have permitt
Autor:
Andrew Kolozsvary, Jianguo Liu, Jae Ho Kim, Kenneth A. Jenrow, Stephen L. Brown, Karen Lapanowski
Publikováno v:
Journal of Neuro-Oncology. 101:449-456
Whole brain irradiation (WBI) is commonly administered therapeutically and is routinely associated with late delayed radiation injuries, manifesting as severe and irreversible cognitive impairment. Neural progenitors within the subgranular zone (SGZ)
Publikováno v:
Journal of Neuro-Oncology. 82:119-124
Radiation-induced optic nerve damage was reduced by ramipril, a prodrug angiotensin-converting enzyme inhibitor (ACEI). This study was to determine the optimum dose and administration time of ramipril for mitigating radiation-induced optic neuropathy