Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kenneth A. Frauwirth"'
Publikováno v:
Encyclopedia of Biological Chemistry III ISBN: 9780128220405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2d781025ee65ec98a9b5ec7df023bdf
https://doi.org/10.1016/b978-0-12-819460-7.00116-x
https://doi.org/10.1016/b978-0-12-819460-7.00116-x
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15425 (2010)
T lymphocytes play a critical role in cell-mediated immune responses. During activation, extracellular and intracellular signals alter T cell metabolism in order to meet the energetic and biosynthetic needs of a proliferating, active cell, but contro
Externí odkaz:
https://doaj.org/article/6dfb412b5ba44b30a42ac96064e73d75
Autor:
Wenxia Song, Stephen B. Melville, Katerina V. Thompson, Ann C. Smith, Daniel C. Stein, John Buchner, Kenneth A. Frauwirth, David L. Popham, Vincent T. Lee, Richard C. Stewart, Richard W. Seyler, Ann M. Stevens, Sarah A. Balcom, Sandra L. Daniel, Najib M. El-Sayed, Gili Marbach-Ad, David M. Mosser, Zhaomin Yang, Stephanie A. Yarwood, Birgit E. Scharf, Jeffrey J. DeStefano, Kevin S. McIver, Florian D. Schubot, Patricia Shields
Publikováno v:
Journal of Microbiology & Biology Education
Journal of Microbiology & Biology Education, Vol 18, Iss 1 (2017)
Journal of Microbiology & Biology Education, Vol 18, Iss 1 (2017)
Misconceptions, also known as alternate conceptions, about key concepts often hinder the ability of students to learn new knowledge. Concept inventories (CIs) are designed to assess students’ understanding of key concepts, especially those prone to
Autor:
Emilee Senkevitch, Alina Kelman, Glendon S. Wu, Anahit Aghvanyan, Ravindra Gopaul, Erikka L. Carr, Kenneth A. Frauwirth, Achmed M. Turay
Publikováno v:
The Journal of Immunology. 185:1037-1044
Activation of a naive T cell is a highly energetic event, which requires a substantial increase in nutrient metabolism. Upon stimulation, T cells increase in size, rapidly proliferate, and differentiate, all of which lead to a high demand for energet
Autor:
Katerina V. Thompson, Kenneth A. Frauwirth, Volker Briken, Najib M. El-Sayed, Sam W. Joseph, Laura Cathcart, David M. Mosser, Brenda L. Fredericksen, Gili Marbach-Ad, Kevin S. McIver, Patricia Shields, Spencer A. Benson, Wenxia Song, Vincent T. Lee, Ann C. Smith, B. Booth Quimby, Katherine C. McAdams, Daniel C. Stein, Richard C. Stewart, Michael Chase
Publikováno v:
CBE Life Sciences Education
This essay describes how the use of a concept inventory has enhanced professional development and curriculum reform efforts of a faculty teaching community. The Host Pathogen Interactions (HPI) teaching team is composed of research and teaching facul
Publikováno v:
The Journal of Immunology. 179:3734-3741
Anergy is an important mechanism of maintaining peripheral immune tolerance. T cells rendered anergic are refractory to further stimulation and are characterized by defective proliferation and IL-2 production. We used a model of in vivo anergy induct
Autor:
Mitchell A. Lazar, Y. Lynn Wang, Kenneth A. Frauwirth, Craig B. Thompson, Shamina M. Rangwala
Publikováno v:
Journal of Biological Chemistry. 277:31781-31788
Thiazolidinediones (TZDs) are widely used for treatment of type 2 diabetes mellitus. Peroxisome proliferator-activated receptor gamma (PPAR gamma) is the molecular target of TZDs and is believed to mediate the apoptotic effects of this class of drugs
Publikováno v:
Journal of Clinical Investigation. 109:295-299
Autor:
Kenneth A. Frauwirth
Publikováno v:
Glutamine in Clinical Nutrition ISBN: 9781493919314
The cells of the vertebrate immune system provide protection from infection by activating a variety of defense mechanisms. During activation, cells may grow in size, proliferate, and produce effector molecules, all of which represent energetically de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c69c047ab6eef64d8b59a5459fdedd
https://doi.org/10.1007/978-1-4939-1932-1_4
https://doi.org/10.1007/978-1-4939-1932-1_4
Publikováno v:
Nature Reviews Immunology. 1:220-228
Activation of T lymphocytes is thought to require at least two signals, one delivered by the T-cell receptor complex after antigen recognition, and one provided on engagement of co-stimulatory receptors, such as CD28. Recent studies are providing clu