Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kenneth A. Frauwirth"'
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15425 (2010)
T lymphocytes play a critical role in cell-mediated immune responses. During activation, extracellular and intracellular signals alter T cell metabolism in order to meet the energetic and biosynthetic needs of a proliferating, active cell, but contro
Externí odkaz:
https://doaj.org/article/6dfb412b5ba44b30a42ac96064e73d75
Autor:
Wenxia Song, Stephen B. Melville, Katerina V. Thompson, Ann C. Smith, Daniel C. Stein, John Buchner, Kenneth A. Frauwirth, David L. Popham, Vincent T. Lee, Richard C. Stewart, Richard W. Seyler, Ann M. Stevens, Sarah A. Balcom, Sandra L. Daniel, Najib M. El-Sayed, Gili Marbach-Ad, David M. Mosser, Zhaomin Yang, Stephanie A. Yarwood, Birgit E. Scharf, Jeffrey J. DeStefano, Kevin S. McIver, Florian D. Schubot, Patricia Shields
Publikováno v:
Journal of Microbiology & Biology Education
Journal of Microbiology & Biology Education, Vol 18, Iss 1 (2017)
Journal of Microbiology & Biology Education, Vol 18, Iss 1 (2017)
Misconceptions, also known as alternate conceptions, about key concepts often hinder the ability of students to learn new knowledge. Concept inventories (CIs) are designed to assess students’ understanding of key concepts, especially those prone to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ee76e6af552e1b5966280df735fa98
https://doi.org/10.1128/jmbe.v18i1.1281
https://doi.org/10.1128/jmbe.v18i1.1281
Autor:
Emilee Senkevitch, Alina Kelman, Glendon S. Wu, Anahit Aghvanyan, Ravindra Gopaul, Erikka L. Carr, Kenneth A. Frauwirth, Achmed M. Turay
Publikováno v:
The Journal of Immunology. 185:1037-1044
Activation of a naive T cell is a highly energetic event, which requires a substantial increase in nutrient metabolism. Upon stimulation, T cells increase in size, rapidly proliferate, and differentiate, all of which lead to a high demand for energet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45752587e7706d53cd517b16d94fa28
https://doi.org/10.4049/jimmunol.0903586
https://doi.org/10.4049/jimmunol.0903586
Autor:
Katerina V. Thompson, Kenneth A. Frauwirth, Volker Briken, Najib M. El-Sayed, Sam W. Joseph, Laura Cathcart, David M. Mosser, Brenda L. Fredericksen, Gili Marbach-Ad, Kevin S. McIver, Patricia Shields, Spencer A. Benson, Wenxia Song, Vincent T. Lee, Ann C. Smith, B. Booth Quimby, Katherine C. McAdams, Daniel C. Stein, Richard C. Stewart, Michael Chase
Publikováno v:
CBE Life Sciences Education
This essay describes how the use of a concept inventory has enhanced professional development and curriculum reform efforts of a faculty teaching community. The Host Pathogen Interactions (HPI) teaching team is composed of research and teaching facul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14a85be8ea3d35734e69ac241e4bd8b
http://europepmc.org/articles/PMC2995757
http://europepmc.org/articles/PMC2995757
Publikováno v:
The Journal of Immunology. 179:3734-3741
Anergy is an important mechanism of maintaining peripheral immune tolerance. T cells rendered anergic are refractory to further stimulation and are characterized by defective proliferation and IL-2 production. We used a model of in vivo anergy induct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927efdb47c3c677c03a6a292af1875ee
https://doi.org/10.4049/jimmunol.179.6.3734
https://doi.org/10.4049/jimmunol.179.6.3734
Autor:
Mitchell A. Lazar, Y. Lynn Wang, Kenneth A. Frauwirth, Craig B. Thompson, Shamina M. Rangwala
Publikováno v:
Journal of Biological Chemistry. 277:31781-31788
Thiazolidinediones (TZDs) are widely used for treatment of type 2 diabetes mellitus. Peroxisome proliferator-activated receptor gamma (PPAR gamma) is the molecular target of TZDs and is believed to mediate the apoptotic effects of this class of drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad560ced2f85d229ea5e3ea90a68eda3
https://doi.org/10.1074/jbc.m204279200
https://doi.org/10.1074/jbc.m204279200
Publikováno v:
Journal of Clinical Investigation. 109:295-299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b7fd2a7d5baf2f8174e31c3b0f09e18
https://doi.org/10.1172/jci0214941
https://doi.org/10.1172/jci0214941
Autor:
Kenneth A. Frauwirth
Publikováno v:
Glutamine in Clinical Nutrition ISBN: 9781493919314
The cells of the vertebrate immune system provide protection from infection by activating a variety of defense mechanisms. During activation, cells may grow in size, proliferate, and produce effector molecules, all of which represent energetically de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c69c047ab6eef64d8b59a5459fdedd
https://doi.org/10.1007/978-1-4939-1932-1_4
https://doi.org/10.1007/978-1-4939-1932-1_4
Publikováno v:
Nature Reviews Immunology. 1:220-228
Activation of T lymphocytes is thought to require at least two signals, one delivered by the T-cell receptor complex after antigen recognition, and one provided on engagement of co-stimulatory receptors, such as CD28. Recent studies are providing clu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc1e047b5ecf307439bd7a01811645d
https://doi.org/10.1038/35105024
https://doi.org/10.1038/35105024
Autor:
Kevin S. McIver, Robert Yuan, Patricia Shields, Gili Marbach-Ad, Vincent T. Lee, Steven W. Hutcheson, Ann C. Smith, Daniel C. Stein, B. Booth Quimby, Lian-Yong Gao, Brenda L. Fredericksen, Wenxia Song, David M. Mosser, Volker Briken, Najib M. El-Sayed, Sam W. Joseph, Kenneth A. Frauwirth
Publikováno v:
Journal of Microbiology & Biology Education, Vol 10, Iss 1, Pp 43-50 (2009)
Journal of Microbiology & Biology Education, Vol 10, Iss 1 (2009)
ResearcherID
Journal of Microbiology & Biology Education, Vol 10, Iss 1 (2009)
ResearcherID
As a group of faculty with expertise and research programs in the area of host-pathogen interactions (HPI), we are concentrating on students’ learning of HPI concepts. As such we developed a concept inventory to measure level of understanding relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd1816cddc0f500dd4ef4923f164387
https://pubmed.ncbi.nlm.nih.gov/23653689
https://pubmed.ncbi.nlm.nih.gov/23653689