Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kenneth A. Applegate"'
Autor:
John A. Glomset, Kenneth R. Applegate
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 10, Pp 1645-1655 (1991)
In a companion study of the effects of acyl chain unsaturation on a series of model sn-1,2-diacylglycerols (DGs) we showed that individual DGs could adopt one of three energy-minimized conformations depending on the number and location of cis double
Autor:
John A. Glomset, Maureen M. Momsen, Weiling C. King, Kenneth R. Applegate, Howard L. Brockman
Publikováno v:
Biophysical journal. 85(4)
Mammalian synaptic membranes appear to contain high proportions of specific, sn-1-stearoyl-2-docosahexaenoyl- and sn-1-stearoyl-2-arachidonoyl phosphoglycerides, but the structural significance of this is unclear. Here we used a standardized approach
Autor:
Kenneth R. Applegate, John A. Glomset
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 10, Pp 1635-1644 (1991)
In a previous modeling study we identified an angle iron-shaped conformation of docosahexaenoic acid and showed that an sn-1-stearoyl diacylglycerol (DG) that contained an sn-2-docosahexaenoyl group in this conformation could adopt a highly regular s
Autor:
Weiling C. King, Kenneth A. Applegate, Trudy M. Forte, Kaare R. Norum, Egil Gjone, Carolyn D. Mitchell, John A. Glomset
Publikováno v:
Annals of the New York Academy of Sciences. 348:224-243
Action of LCAT on the plasma of patients afflicted with familial LCAT deficiency shifts the distribution of C apolipoproteins from lipoproteins of d less than 1.019 g/ml to lipoproteins of d greater than 1.109 g/ml, and causes an opposite shift in th
Autor:
Carolyn D. Mitchell, Egil Gjone, John A. Glomset, Alex V. Nichols, Elaine L. Gong, Weiling C. King, Kaare R. Norum, Kenneth R. Applegate
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 35:3-30
To study the metabolism of the abnormal plasma lipoproteins in familial lecithin:cholesterol acyltransferase deficiency we performed five dietary experiments designed to perturb their distribution and composition. Four patients with the disease were
Autor:
John A. Glomset, Trudy M. Forte, Weiling C. King, Egil Gjone, Carolyn D. Mitchell, Kaare R. Norum, Kenneth R. Applegate
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 5, Pp 625-634 (1980)
We have isolated and characterized a subfraction of high density lipoproteins, rich in apolipoprotein E, from the plasma of patients afflicted with familial lecithin: cholesterol acyltransferase deficiency. Prepared by succes- sive ultracentrifugal f
Autor:
Carolyn D. Mitchell, Weiling C. King, Egil Gjone, Kaare R. Norum, John A. Glomset, Trudy M. Forte, Kenneth R. Applegate
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 8, Pp 1116-1127 (1980)
Studies of different sized lipoproteins of d < 1.006 g/ml from patients with familial 1ecithin:cholesterol acyltransferase deficiency have yielded new evidence of abnormalities in this lipoprotein class. Lipoproteins of all sizes contain high amounts
Autor:
John R. Chipley, Kenneth L. Applegate
Publikováno v:
Mycologia. 66:436-445
Germination of spores of the toxinogenic organism Aspergillus flavus NRRL-3145, previously exposed to specific gamma radiation levels, resulted in a greater production of aflatoxins B1 and B2 follo...
Autor:
John A. Glomset, Weiling C. King, Egil Gjone, C.H. Chen, Kenneth R. Applegate, Kaare R. Norum
Publikováno v:
Journal of Lipid Research, Vol 25, Iss 3, Pp 269-282 (1984)
We studied the effects of the 1ecithin:cholesterol acyl- transferase reaction on the size and composition of the small spherical high density lipoproteins of patients afflicted with fa- milial 1ecithin:cholesterol acyltransferase deficiency. We isola
Autor:
Kaare R. Norum, Alex V. Nichols, Elaine L. Gong, Weiling C. King, V G Cabana, Kenneth R. Applegate, John A. Glomset, Carolyn D. Mitchell, Egil Gjone, Trudy M. Forte, John J. Albers
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 35:31-55
To study the effect of lecithin: cholesterol acyltransferase (LCAT) on the plasma lipoproteins of patients with familial LCAT deficiency, whole plasma or the lipoprotein fraction of d < 1.006 g/ml (VLDL) was incubated in the presence of LCAT and subs