Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Kenneth Shankland"'
Autor:
Stewart F. Parker, Nicholas P. Funnell, Kenneth Shankland, Elena A. Kabova, Thomas Häußner, Hans-Joachim Hasselbach, Sascha Braune, Christoph Kobler, Peter W. Albers
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The amino acid l-methionine is an essential amino acid and is commonly used as a feed supplement in terrestrial animals. It is less suitable for marine organisms because it is readily excreted. It is also highly water soluble and this result
Externí odkaz:
https://doaj.org/article/bb624013757d4d96bb37521e378d0756
Autor:
Thomas Hibbard, Bildad Nyambura, Peter Scholes, Mihaela Totolici, Kenneth Shankland, Hisham Al-Obaidi
Publikováno v:
Journal of Pharmaceutical Sciences. 112:195-203
The crystal structures of four novel dicarboxylic acid salts of ciprofloxacin (CFX) with modified physicochemical properties, prepared by mechanochemical synthesis and solvent crystallization, are reported. A series of dicarboxylic acids of increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6b426c063bfcc37cc089fc0548d790
https://doi.org/10.1016/j.xphs.2022.08.008
https://doi.org/10.1016/j.xphs.2022.08.008
Autor:
Dimitri Alvarez-Dorta, Elisa I. León, Ángeles Martín, Alan R. Kennedy, Inés Pérez-Martín, Kenneth Shankland, Ernesto Suárez
Publikováno v:
The Journal of Organic Chemistry. 87:14940-14947
As shown by X-ray crystallography, crystals of 3β-acetoxy-16,17-seco-17,20-dioxopregn-5-ene-16-nitrile are dimorphic. The regioselectivity of the Norrish–Yang type II photocyclization under visible light of this steroidal 1,2-diketone, which bears
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d6e9e55279390376ea3766e4b5d99e
https://doi.org/10.1021/acs.joc.2c01855
https://doi.org/10.1021/acs.joc.2c01855
Autor:
Divyashree Ravishankar, Maryam Salamah, Alda Attina, Radhika Pothi, Thomas M. Vallance, Muhammad Javed, Harry F. Williams, Eman M. S. Alzahrani, Elena Kabova, Rajendran Vaiyapuri, Kenneth Shankland, Jonathan Gibbins, Katja Strohfeldt, Francesca Greco, Helen M. I. Osborn, Sakthivel Vaiyapuri
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The constant increase in cardiovascular disease rate coupled with significant drawbacks of existing therapies emphasise the necessity to improve therapeutic strategies. Natural flavonoids exert innumerable pharmacological effects in humans.
Externí odkaz:
https://doaj.org/article/0eeaaa4bdcc84143851f1fbae8335e22
Autor:
Qi Lin, Hao Lan, Chunmiao Ma, Ryan T. Stendall, Kenneth Shankland, Rebecca A. Musgrave, Peter N. Horton, Carsten Baldauf, Hans-Jörg Hofmann, Craig P. Butts, Manuel M. Müller, Alexander John Andre Cobb
Publikováno v:
Angewandte Chemie International Edition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5a833bc885a695fe2558e779796031
https://doi.org/10.1002/anie.202305326
https://doi.org/10.1002/anie.202305326
Autor:
Alexander Cobb, Qi Lin, Hao Lan, Kenneth Shankland, Rebecca Musgrave, Peter Horton, Carsten Baldauf, Hans-Jorg Hofmann, Craig Butts, Manuel Mueller, Chunmiao Ma
We report the first structures of an unusual 13/11-helix (alternating i,i+1 {NH--O=C} and i,i+3 {C=O--H—N} H-bonds) formed by a heteromeric 1:1 se-quence of alpha- and delta-amino acids, using both XRD and NMR. Whilst intramolecular hydrogen bonds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2673462c849c95f27090045b7acc113
https://doi.org/10.26434/chemrxiv-2023-ks4t3
https://doi.org/10.26434/chemrxiv-2023-ks4t3
Publikováno v:
CrystEngComm. 24:4551-4555
An effective and efficient method for dealing with ring systems during global optimisation-based crystal structure determination from powder diffraction data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a50243965094e5649560bff0362f42
https://doi.org/10.1039/d2ce00520d
https://doi.org/10.1039/d2ce00520d
Publikováno v:
Crystals, Vol 10, Iss 1, p 42 (2020)
Co-crystallization is a promising approach to improving both the solubility and the dissolution rate of active pharmaceutical ingredients. Crystal structure determination from powder diffraction data plays an important role in determining co-crystal
Externí odkaz:
https://doaj.org/article/4aff61f353d44b9abb2820da170d2482
Autor:
Alexander J. A. Cobb, Kenneth Shankland, Callum D Johnston, Nicholas R. Lees, Laura A Bryant, Hannah Straker
Publikováno v:
Advanced Synthesis & Catalysis. 363:4067-4074
The organocatalytic transformation of resorcinols is extremely rare. In this article, we report a highly enantioselective, organocatalytic intramolecular cyclization of these systems by a Friedel-Crafts-type 1,4-addition using a Jorgensen-Hayashi-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010f177fe705e7c4f543c910da66f997
https://doi.org/10.1002/adsc.202100647
https://doi.org/10.1002/adsc.202100647