Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kenneth, Nephew"'
Autor:
Horacio Cardenas, Fang Fang, Guanglong Jiang, Susan M. Perkins, Chi Zhang, Robert E. Emerson, George Hutchins, Harold N. Keer, Yunlong Liu, Daniela Matei, Kenneth Nephew
Publikováno v:
Epigenetics, Vol 16, Iss 11, Pp 1201-1216 (2021)
High-grade serous ovarian cancer (HGSOC) harbours aberrant epigenetic features, including DNA methylation. In this study we delineate pathways and networks altered by DNA methylation and associated with HGSOC initiation and progression to a platinum-
Externí odkaz:
https://doaj.org/article/ae8d07e5d9604a41bb9960295ddd78e5
Autor:
Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hulsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew, Kathy D. Miller, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:1345-1360
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S9: Results of ATAC-seq of primary and TONSL-immortalized cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aebc890399e5bfe96f54d95a43428de
https://doi.org/10.1158/0008-5472.22633261.v1
https://doi.org/10.1158/0008-5472.22633261.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a02b10f9fff51b50bf5355116b3f214
https://doi.org/10.1158/0008-5472.c.6599674.v1
https://doi.org/10.1158/0008-5472.c.6599674.v1
Supplementary Data from TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Contains additional materials and methods and supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5b3f2a2a751789590276560b96ae52
https://doi.org/10.1158/0008-5472.22633315
https://doi.org/10.1158/0008-5472.22633315
Akademický článek
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Autor:
Raphaël Mourad, Pei-Yin Hsu, Liran Juan, Changyu Shen, Prasad Koneru, Hai Lin, Yunlong Liu, Kenneth Nephew, Tim H Huang, Lang Li
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113354 (2014)
In the cell nucleus, each chromosome is confined to a chromosome territory. This spatial organization of chromosomes plays a crucial role in gene regulation and genome stability. An additional level of organization has been discovered at the chromoso
Externí odkaz:
https://doaj.org/article/55b25c94bc6042e18e4a62c69ba3762d
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70641 (2013)
Pure anti-estrogen fulvestrant has been shown to be a promising ER antagonist for locally advanced and metastatic breast cancer. Unfortunately, a significant proportion of patients developed resistance to this type of endocrine therapy but the molecu
Externí odkaz:
https://doaj.org/article/18c2394374ba44ebac735d45666446d3
Autor:
Zhigang Cai, Reuben Kapur, Xiaoyu Lu, Chi Zhang, Sai Nelanuthala, Jonathan Kotzin, Adam Williams, Jorge Henao-Mejia, Fabiola Aguilera, Abigail Hadley, Fang Fang, Kenneth Nephew
Publikováno v:
Blood. 136:30-30
Diabetes mellitus (DM) is a risk factor for cancer development. However, the role of DM induced hyperglycemic stress (HG) in the development of blood cancer is poorly understood, largely due to lack of appropriate animal models. Epidemiologic studies