Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kenneth, Nakahara"'
Autor:
Ilan R. Kirsch, Kenneth Nakahara, Oleg K. Glebov, Peter W. Soballe, John Denobile, Luz Rodriguez, Janet Cliatt
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 15:2253-2262
Aberrant crypt foci (ACF) are considered the earliest identifiable preneoplastic colonic lesions; thus, a greater understanding of the nature of genetic changes underlying the transformation of normal colonic mucosa (NM) into ACF may provide insight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50ae5b99c8618bead9bc3a9ee52b473
https://doi.org/10.1158/1055-9965.epi-05-0694
https://doi.org/10.1158/1055-9965.epi-05-0694
Autor:
Anna V. Roschke, Bridget P. Keenan, Kenneth Nakahara, Yue Cheng, Zhenhua Zhang, Peter D. Aplan
Aberrant repair of DNA double-strand breaks (DSBs) is thought to be important in the generation of gross chromosomal rearrangements (GCRs). To examine how DNA DSBs might lead to GCRs, we investigated the repair of a single DNA DSB in a structurally u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af7bdbbdfe60fda70110270b36f1102
https://europepmc.org/articles/PMC2797445/
https://europepmc.org/articles/PMC2797445/
Autor:
Kenneth Nakahara, Ilan R. Kirsch, Stanley Lipkowitz, Kathryn M. Tchorz, Verena Gobel, Mary L. Varterasian
Publikováno v:
Journal of Biological Chemistry. 267:21065-21071
Human cDNA clones for NSCL-1 and NSCL-2, two basic domain helix-loop-helix (bHLH) genes expressed predominantly in the developing nervous system, were obtained from a fetal brain cDNA library. The full-length transcripts and the genomic structures we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4681847ba379ccbff7f3ba9efeb9822d
https://doi.org/10.1016/s0021-9258(19)36798-5
https://doi.org/10.1016/s0021-9258(19)36798-5
Autor:
Casey Jo Humbyrd, Gary Gordon, Jean Jenkins, Steven Gallinger, Oleg K. Glebov, Aby Buchbinder, Luz Rodriguez, Henry T. Lynch, Ilan R. Kirsch, Kenneth Nakahara, Janet Cliatt, Patrick M. Lynch, John Denobile, Sherri Patterson, Peter W. Soballe, Ernest T. Hawk
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 15(7)
A clinical trial was recently conducted to evaluate the safety and efficacy of a selective inhibitor of cyclooxygenase-2 (celecoxib) in hereditary nonpolyposis colon cancer patients. In a randomized, placebo-controlled phase I/II multicenter trial, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9979bdb32a6c1743f9518bc5f6666800
https://pubmed.ncbi.nlm.nih.gov/16835340
https://pubmed.ncbi.nlm.nih.gov/16835340
Autor:
Oleg K, Glebov, Luz M, Rodriguez, Kenneth, Nakahara, Jean, Jenkins, Janet, Cliatt, Casey-Jo, Humbyrd, John, DeNobile, Peter, Soballe, Richard, Simon, George, Wright, Patrick, Lynch, Sherri, Patterson, Henry, Lynch, Steven, Gallinger, Aby, Buchbinder, Gary, Gordon, Ernest, Hawk, Ilan R, Kirsch
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 12(8)
Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18f3f39708a8acc983385fa0d29c2d8c
https://pubmed.ncbi.nlm.nih.gov/12917207
https://pubmed.ncbi.nlm.nih.gov/12917207
Autor:
Donald W. Hadley, Ilan R. Kirsch, David J. Liewehr, Eileen Dimond, Jean Jenkins, Seth M. Steinberg, Liam Grogan, Kenneth Nakahara
Publikováno v:
Archives of internal medicine. 163(5)
Background Genetic testing to refine cancer risk is available. However, little is known about factors affecting the uptake of testing for the most common hereditary colon cancer, hereditary nonpolyposis colorectal cancer. This study investigated atti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3c84737855680d9de91bac452042a0
https://pubmed.ncbi.nlm.nih.gov/12622604
https://pubmed.ncbi.nlm.nih.gov/12622604
Publikováno v:
Science. 216:301-303
A human immunoglobulin heavy chain (γ 4) gene is mapped by chromosome hybridization in situ. This gene is located at band 14q32, a site commonly involved in a chromosomal translocation characterist...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc8ad633958cd37de7e7301a76226c4
https://doi.org/10.1126/science.6801764
https://doi.org/10.1126/science.6801764
Autor:
Michael P. Davey, Ilan R. Kirsch, Thomas A. Waldmann, O. W. Mcbride, Kenneth Nakahara, J P Johnson, Virginia L. Bertness
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 85(23)
We describe a t(14;14)(q11;q32) translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia (AT). By using a battery of joining (J)-segment probes from the T-cell receptor (TCR) alpha-chain locus TCRA, three distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08aaa44403fe7f5d995d38517a72617b
https://pubmed.ncbi.nlm.nih.gov/3194425
https://pubmed.ncbi.nlm.nih.gov/3194425
Autor:
Barton F. Haynes, Ilan R. Kirsch, Peter D. Aplan, Joanne Kurtzberg, Thomas A. Waldmann, David I. Cohen, Michael S. Hershfield, Michael P. Davey, Kathryn M. Tchorz, Kenneth Nakahara, C. G. Begley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 86(6)
We have studied a leukemic stem-cell line, DU.528, that is able to differentiate into myeloid and lymphoid cells. The leukemic cells have a translocation between chromosomes 1 and 14, t(1;14)(p33;q11), which we have molecularly cloned and sequenced.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b560664855bcefa0ef21ee64270491
https://pubmed.ncbi.nlm.nih.gov/2467296
https://pubmed.ncbi.nlm.nih.gov/2467296