miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling.

Autor: Hossein Sendi, Ivy Mead, Meimei Wan, Marjan Mehrab-Mohseni, Kenneth Koch, Anthony Atala, Herbert L Bonkovsky, Colin E Bishop

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0200847 (2018)

To investigate the role of miR-122 in the development and regression of non-alcoholic fatty liver disease (NAFLD) in vitro, we used multicellular 3D human liver organoids developed in our laboratory. These organoids consist of primary human hepatocyt

Externí odkaz: https://doaj.org/article/4f6d875a989b44139ca31cae6498246e

S1628 Physiological Impact of Spinal Cord Stimulation in Gastroparesis Patients With Chronic Abdominal Pain

Autor: Jared Rejeski, Leonardo Kapural, Kenneth Koch

Publikováno v: American Journal of Gastroenterology. 117:e1164-e1165

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d0d76974269ceea9b010ae1fa5d62ef
https://doi.org/10.14309/01.ajg.0000863152.26422.0f

Headache in Children

Autor: Jessica L. Klein, Thomas Kenneth Koch

Publikováno v: Pediatrics In Review. 41:159-171

1. Jessica Klein, MD* 2. Thomas Koch, MD* 1. *Division of Pediatric Neurology, Medical University of South Carolina, Charleston, SC * Abbreviations: ICHD-3: : third edition of the International Classification of Headache Disorders IV: : intravenous M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770489bfebdb691271ef7797d79206c7
https://doi.org/10.1542/pir.2017-0012

Functional Dyspepsia and Gastroparesis in Tertiary Care are Interchangeable Syndromes With Common Clinical and Pathologic Features

Autor: Pankaj J. Pasricha, Madhusudan Grover, Katherine P. Yates, Thomas L. Abell, Cheryl E. Bernard, Kenneth L. Koch, Richard W. McCallum, Irene Sarosiek, Braden Kuo, Robert Bulat, Jiande Chen, Robert J. Shulman, Linda Lee, James Tonascia, Laura A. Miriel, Frank Hamilton, Gianrico Farrugia, Henry P. Parkman, Pankaj Jay Pasricha, Robert Burns, Guillermo Barahona Hernandez, Megan McKnight, April Mendez, Kyle Staller, Andrea Thurler, Christopher Velez, Casey Silvernale, Zubair Malik, Alan Maurer, Amiya Palit, Natalia Vega, Denise Vasquez, Sean Connery, Karina Espino, Marvin Friedman, Thomas Abell, Abigail Stocker, Bridget Cannon, Lindsay McElmurray, Kelly Cooper, Catherine McBride, Kenneth Koch, Lynn Baxter, Anya Brown, Paula Stuart, Amirah Abdullah, William Snape, Nata DeVole, Karen Earle, Kjersti Kirkeby, Candice Lee, Mimi Lin, Doug Troyer, Anna von Bakonyi, Robert Shulman, Bruno Chumpitazi, Liz Febo-Rodriguez, John Hollier, Cynthia Bouette, Heather Charron, Samuel Nurko, Stephanie Wall, Madeline Kane, Kent Williams, Lina Yossef-Salameh, Frederick Woodley, Cheryl Bernard, Jose Serrano, Sherry Hall, Stephen James, Rebecca Torrance, Margaret Adamo, Patricia Belt, John Dodge, Michele Donithan, Milana Isaacson, Jill Meinert, Laura Miriel, Emily Sharkey, Jacqueline Smith, Michael Smith, Alice Sternberg, Mark Van Natta, Annette Wagoner, Laura Wilson, Goro Yamada, Katherine Yates

Publikováno v: Gastroenterology. 160(6)

Background The aim of this study was to clarify the pathophysiology of functional dyspepsia (FD), a highly prevalent gastrointestinal syndrome, and its relationship with the better-understood syndrome of gastroparesis. Methods Adult patients with chr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deda79c9aaf7c38d9b9981242e2bc90c
https://pubmed.ncbi.nlm.nih.gov/33621562

Functional Obstructive Gastroparesis: Effect of Laparoscopic Pyloroplasty on Symptoms, Gastric Emptying, and Gastric Myoelectrical Activity After Successful Endoscopic Pyloric Therapies

Autor: Jennifer Wellington, Kenneth Koch, Paula Stuart

Publikováno v: American Journal of Gastroenterology. 112:S662-S663

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c59c58f70fa9e089813c08dfe937303
https://doi.org/10.1038/ajg.2017.310