Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kennedy M. Taveras"'
Autor:
Kennedy M. Taveras, Sebastian Thordal Le Quement, Thomas E. Nielsen, Michael Givskov, Nitin Subhash Nandurkar, Vitaly V. Komnatnyy
Publikováno v:
European Journal of Organic Chemistry. 2015:3524-3530
We report the results of our recent investigations into the reactivity of cyclic solid-supported N-acyliminium ions. An intermolecular Mannich-type transformation of these intermediates was used to generate libraries of substituted lactams. Masked al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc936d6ea06ef2f3fb484d2579a889e5
https://doi.org/10.1002/ejoc.201500054
https://doi.org/10.1002/ejoc.201500054
Publikováno v:
Tetrahedron Letters. 60:151105
A new synthesis of isoindolinones was discovered during a screening campaign aimed at the development of novel methods for the synthesis of pyridone-EZH2 inhibitor analogues. The reaction proceeds via an intramolecular [4+2] cycloaddition of a pyrido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dd8c40eb96dca8aee20c58870f84003
https://doi.org/10.1016/j.tetlet.2019.151105
https://doi.org/10.1016/j.tetlet.2019.151105
Autor:
Michael Givskov, Nitin Subhash Nandurkar, Vitaly V. Komnatnyy, Robin Frauenlob, Kennedy M. Taveras, Sebastian Thordal Le Quement, Rico Petersen, Katrine Qvortrup, Thomas E. Nielsen
Publikováno v:
Tetrahedron Letters. 52:7121-7124
An efficient method for the solid-phase synthesis of hydroxamic acids is described. The method comprises the nucleophilic displacement of esters immobilized on PEGA resins with hydroxylamine/sodium hydroxide in isopropanol. The hydroxyaminolysis prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012eed2a42e003ccaaa5dc69c58177fb
https://doi.org/10.1016/j.tetlet.2011.10.103
https://doi.org/10.1016/j.tetlet.2011.10.103
Autor:
Kazuo Nakai, Xiang Wang, Julia L. Fox, Benjamin Z. Stanton, Angela N. Koehler, Stuart L. Schreiber, James K. Chen, Lee F. Peng, Jay Duffner, Joel M. Hyman, Kennedy M. Taveras, Nicole Maloof, Sam W. Lee, Anna Mandinova
Publikováno v:
Nature chemical biology
Small-molecule inhibition of extracellular proteins that activate membrane receptors has proven to be extremely challenging. Diversity-oriented synthesis and small-molecule microarrays enabled the discovery of robotnikinin, a small molecule that bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1356bce4a8b450cbf643db749a39a7ff
http://europepmc.org/articles/PMC2770933
http://europepmc.org/articles/PMC2770933
Publikováno v:
Chemical communications (Cambridge, England). 47(4)
In this paper we describe a highly effective surface modification of SU-8 microparticles, the attachment of appropriate linkers for solid-supported synthesis, and the successful chemical modification of these particles via controlled multi-step organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f97b9ded5d183a52f568f6cc79ed05
https://pubmed.ncbi.nlm.nih.gov/21063592
https://pubmed.ncbi.nlm.nih.gov/21063592