Protons and High-Linear Energy Transfer Radiation Induce Genetically Similar Lymphomas With High Penetrance in a Mouse Model of the Aging Human Hematopoietic System.

Autor: Patel R; Department of Radiation Oncology, Duke University, Durham, North Carolina., Zhang L; Department of Medicine, Case Western Reserve University, Cleveland, Ohio., Desai A; Department of Medicine, Case Western Reserve University, Cleveland, Ohio; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio., Hoenerhoff MJ; Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan., Kennedy LH; Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan., Radivoyevitch T; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio., La Tessa C; University of Trento, Trento, Italy; Trento Institute for Fundamental Physics and Applications TIFPA-INFN, Trento, Italy., Gerson SL; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio., Welford SM; Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida; Department of Radiation Oncology, University of Miami, Miami, Florida. Electronic address: scott.welford@med.miami.edu.

Publikováno v: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2020 Nov 15; Vol. 108 (4), pp. 1091-1102. Date of Electronic Publication: 2020 Jul 04.

Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure.

Autor: Patel R; Department of Pharmacology, Case Western Reserve University, Cleveland, OH, USA., Zhang L; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA., Desai A; Department of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA., Hoenerhoff MJ; In Vivo Animal Core Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI, USA., Kennedy LH; In Vivo Animal Core Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI, USA., Radivoyevitch T; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA., Ban Y; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Chen XS; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.; Department of Public Health Sciences, University of Miami, Miami, FL, USA., Gerson SL; Department of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA., Welford SM; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. scott.welford@med.miami.edu.; Department of Radiation Oncology, University of Miami, Miami, FL, USA. scott.welford@med.miami.edu.

Publikováno v: Leukemia [Leukemia] 2019 May; Vol. 33 (5), pp. 1135-1147. Date of Electronic Publication: 2018 Oct 01.

Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1.

Autor: Morland C; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; Institute for Behavioral Sciences, Faculty of Health Sciences, Oslo and Akershus University College, NO-0167 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Andersson KA; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; Institute for Behavioral Sciences, Faculty of Health Sciences, Oslo and Akershus University College, NO-0167 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Haugen ØP; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway., Hadzic A; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; Institute for Behavioral Sciences, Faculty of Health Sciences, Oslo and Akershus University College, NO-0167 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Kleppa L; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Gille A; Institute for Experimental and Clinical Pharmacology and Toxicology, Mannheim Medical Faculty, Heidelberg University, D-68169 Mannheim, Germany., Rinholm JE; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Palibrk V; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway., Diget EH; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; Center for Healthy Aging, Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark., Kennedy LH; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Stølen T; K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway., Hennestad E; Laboratory of Neural Computation, Department of Physiology, University of Oslo, NO-0317 Oslo, Norway., Moldestad O; Centre for Rare Disorders, Oslo University Hospital, Rikshospitalet, NO-0424 Oslo, Norway., Cai Y; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway., Puchades M; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Offermanns S; Max-Planck-Institute for Heart and Lung Research, Department of Pharmacology, D-61231 Bad Nauheim, Germany., Vervaeke K; Laboratory of Neural Computation, Department of Physiology, University of Oslo, NO-0317 Oslo, Norway., Bjørås M; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway., Wisløff U; K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway., Storm-Mathisen J; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway., Bergersen LH; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316 Oslo, Norway.; The Synaptic Neurochemistry Lab, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, Healthy Brain Ageing Centre, University of Oslo, NO-0317 Oslo, Norway.; Center for Healthy Aging, Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.

Publikováno v: Nature communications [Nat Commun] 2017 May 23; Vol. 8, pp. 15557. Date of Electronic Publication: 2017 May 23.

Effects of in utero exposure of C57BL/6J mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin on epidermal permeability barrier development and function.

Autor: Muenyi CS; Department of Biological Sciences, and., Carrion SL, Jones LA, Kennedy LH, Slominski AT, Sutter CH, Sutter TR

Publikováno v: Environmental health perspectives [Environ Health Perspect] 2014 Oct; Vol. 122 (10), pp. 1052-8. Date of Electronic Publication: 2014 Jun 06.

2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.

Autor: Kennedy LH; Department of Chemistry, University of Memphis, Memphis, TN, USA., Sutter CH, Leon Carrion S, Tran QT, Bodreddigari S, Kensicki E, Mohney RP, Sutter TR

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2013 Mar; Vol. 132 (1), pp. 235-49. Date of Electronic Publication: 2012 Nov 14.