Genetic signatures for Helicobacter pylori strains of West African origin.

Autor: Kennady K Bullock, Carrie L Shaffer, Andrew W Brooks, Ousman Secka, Mark H Forsyth, Mark S McClain, Timothy L Cover

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0188804 (2017)

Helicobacter pylori is a genetically diverse bacterial species that colonizes the stomach in about half of the human population. Most persons colonized by H. pylori remain asymptomatic, but the presence of this organism is a risk factor for gastric c

Externí odkaz: https://doaj.org/article/a14eaf83e1294edcb764c69ae5979e0c

Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer

Autor: Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio, Fiona E. Yull

Publikováno v: BMC cancer. 22(1)

Background Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approach is to target the large popu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0ab065299d161f657efeffe543ebde
https://pubmed.ncbi.nlm.nih.gov/35513776

Abstract 2728: Modulation of NFkappaB signaling influences tumor associated macrophage phenotypes in murine models of breast cancer

Autor: Alyssa R. Merkel, Todd D. Giorgio, Evan B. Glass, Dominique Parker, Alyssa Hoover, Fiona E. Yull, Julie A. Rhoades, Kennady K. Bullock, Richard Maynard, Andrew J. Wilson

Publikováno v: Cancer Research. 81:2728-2728

Tumor associated macrophages (TAMs) often exist in high densities in breast tumors and are associated with adverse clinical outcomes. TAM repolarization as a strategy to shift the breast cancer microenvironment from immunosuppressive to immunostimula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cac4a1db5e822b5c32a91e961e5bf66
https://doi.org/10.1158/1538-7445.am2021-2728

Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer

Autor: Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio, Fiona E. Yull

Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)

Abstract Background Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approach is to target the l

Externí odkaz: https://doaj.org/article/695878c019a54c44a19092e66e5e5079

HDAC inhibitors induce LIFR expression and promote a dormancy phenotype in breast cancer.

Autor: Clements ME; Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Center for Bone Biology, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Holtslander L; Vanderbilt Center for Bone Biology, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Edwards C; Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Center for Bone Biology, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Todd V; Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Center for Bone Biology, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Dooyema SDR; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN, USA., Bullock K; Vanderbilt Center for Bone Biology, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA., Bergdorf K; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA., Zahnow CA; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Connolly RM; Cancer Research@UCC, College of Medicine and Health, University College Cork, Cork, Ireland.; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Johnson RW; Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA. rachelle.johnson@vumc.org.; Vanderbilt Center for Bone Biology, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. rachelle.johnson@vumc.org.; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. rachelle.johnson@vumc.org.

Publikováno v: Oncogene [Oncogene] 2021 Aug; Vol. 40 (34), pp. 5314-5326. Date of Electronic Publication: 2021 Jul 10.