Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kenna M, Shaw"'
Autor:
Shubham Pant, Funda Meric-Bernstam, Vivek Subbiah, Kenna M. Shaw, Kenneth R. Hess, Xiaofeng Zheng, Kavitha Balaji, Jaffer A. Ajani, Mark J. Routbort, Scott Kopetz, Mariela Blum-Murphy, Kanwal Pratap Singh Raghav, Russell Broaddus, Mehmet Esat Demirhan, Milind Javle, David S. Hong, Apostolia Maria Tsimberidou, Jordi Rodon, Sarina Anne Piha-Paul, Ecaterina Ileana Dumbrava
Publikováno v:
JCO Precision Oncology. :1-12
PURPOSE Human epidermal growth factor receptor 2 (HER2) is an effective therapeutic target in breast and gastric and gastroesophageal junction cancers. However, less is known about the prevalence of ERBB2 ( HER2) amplification and the efficacy of HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23695bf770675dc1e0f145dc91472c4f
https://doi.org/10.1200/po.18.00345
https://doi.org/10.1200/po.18.00345
Autor:
Ecaterina E Ileana, Dumbrava, Kavitha, Balaji, Kanwal, Raghav, Kenneth, Hess, Milind, Javle, Mariela, Blum-Murphy, Jaffer, Ajani, Scott, Kopetz, Russell, Broaddus, Mark, Routbort, Mehmet, Demirhan, Xiaofeng, Zheng, Shubham, Pant, Apostolia M, Tsimberidou, Vivek, Subbiah, David S, Hong, Jordi, Rodon, Kenna M, Shaw, Sarina A, Piha-Paul, Funda, Meric-Bernstam
Publikováno v:
JCO Precision Oncology
PURPOSE Human epidermal growth factor receptor 2 (HER2) is an effective therapeutic target in breast and gastric and gastroesophageal junction cancers. However, less is known about the prevalence of ERBB2 (HER2) amplification and the efficacy of HER2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ed30b36928cf373d8c45158c94807ad
https://pubmed.ncbi.nlm.nih.gov/32923865
https://pubmed.ncbi.nlm.nih.gov/32923865
Autor:
Makoto Kamei, Brant M. Weinstein, Matthew R. Swift, Kameha Bell, Van N. Pham, Kenna M. Shaw, Brigid D. Lo, Mayumi F Miller, Daniel Castranova, Paul J. Paukstelis, Andrew E. Davis, Jesús Torres-Vázquez
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:655-662
Objective— Understanding the mechanisms regulating normal and pathological angiogenesis is of great scientific and clinical interest. In this report, we show that mutations in 2 different aminoacyl-transfer RNA synthetases, threonyl tRNA synthetase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed04c52237acc50c3d0f3e5788fc481
https://doi.org/10.1161/atvbaha.115.307087
https://doi.org/10.1161/atvbaha.115.307087
Autor:
Mehdi Mesri, Akhilesh Pandey, Lauren C. Tang, Shayan C. Avanessian, Stefani N. Thomas, Emily S. Boja, Chen Huang, Lili Blumenberg, Mauricio Oberti, Peter B. McGarvey, Karen A. Ketchum, Zhen Zhang, Amanda G. Paulovich, Samuel H. Payne, Ratna R. Thangudu, Karsten Krug, Gad Getz, Shuang Cai, David I. Heiman, Karl R. Clauser, David F. Ransohoff, Nathan Edwards, Ie Ming Shih, Chet Birger, Gordon Whiteley, Michael Snyder, Tara Hiltke, Paul A. Rudnick, Christopher R. Kinsinger, Philipp Mertins, Subha Madhavan, Henry Rodriguez, Melinda E. Sanders, Jingqin Luo, Xian Chen, Yosef E. Maruvka, Kenna M. Shaw, George Miles, Shunqiang Li, Eric Kuhn, Lisa J. Zimmerman, Zhiao Shi, Christopher G. Maher, Stephen E. Stein, Thomas F. Westbrook, Matthew A. Wyczalkowski, Daniel W. Chan, Bo Wen, Xi Steven Chen, Song Cao, Hui Zhang, Yifat Geffen, Jason E. McDermott, Yuxing Liao, Yue Wang, Yingming Zhao, David L. Tabb, Mathangi Thiagarajan, D. R. Mani, Matthew J. Ellis, Forest M. White, Robert Rivers, Heng Zhu, Yongchao Dou, David Fenyö, Antonio Colaprico, Shankha Satpathy, Eric J. Jaehnig, Jeffrey R. Whiteaker, Li Ding, Meenakshi Anurag, Karin D. Rodland, Andrew N. Hoofnagle, Ana I. Robles, Kelly V. Ruggles, Steven A. Carr, Richard D. Smith, Jacob J. Kennedy, Tao Liu, Robbert J.C. Slebos, Maciej Wiznerowicz, Daniel C. Liebler, M. Harry Kane, Jonathan T. Lei, Alla Karpova, Ramani B. Kothadia, Douglas A. Levine, Bing Zhang, Michael A. Gillette, Jarey Wang
Publikováno v:
Cell
Elsevier
Elsevier
SUMMARY The integration of mass spectrometry-based proteomics with next-generation DNA and RNA sequencing profiles tumors more comprehensively. Here this “proteogenomics” approach was applied to 122 treatment-naive primary breast cancers accrued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59aa97d338438527c048cae9e15d045
http://europepmc.org/articles/PMC8077737
http://europepmc.org/articles/PMC8077737
Autor:
David L. Tabb, Zhiao Shi, Samuel H. Payne, Peter B. McGarvey, Matthew J. Ellis, Jing Wang, Steven J. Skates, David F. Ransohoff, Kent Shaddox, Ie Ming Shih, Gordon Whiteley, Michael Snyder, Nathan Edwards, Jeffrey R. Whiteaker, Tao Liu, Forest M. White, Xian Chen, Douglas A. Levine, Christopher R. Kinsinger, Sean Wang, Sangtae Kim, Karin D. Rodland, Qi Liu, Melinda E. Sanders, Michael A. Gillette, Robert J. Coffey, Xiaojing Wang, Steven A. Carr, Philipp Mertins, Bing Zhang, Robbert J.C. Slebos, Pei Wang, Emily S. Boja, Lisa J. Zimmerman, Daniel C. Liebler, Matthew C. Chambers, Henry Rodriguez, Zhen Zhang, Akhilesh Pandey, Richard D. Smith, Robert Rivers, Subha Madhavan, Karen A. Ketchum, Li Ding, Yue Wang, R. Reid Townsend, Sherri R. Davies, David Fenyö, Hui Zhang, D. R. Mani, Heng Zhu, Yingming Zhao, Jason E. McDermott, Paul A. Rudnick, Stephen E. Stein, Tara Hiltke, Mehdi Mesri, Jing Zhu, Andrew N. Hoofnagle, Daniel W. Chan, Amanda G. Paulovich, Eric Kuhn, Karl R. Klauser, Kenna M. Shaw
Publikováno v:
Nature. 513:382-387
Extensive genomic characterization of human cancers presents the problem of inference from genomic abnormalities to cancer phenotypes. To address this problem, we analysed proteomes of colon and rectal tumours characterized previously by The Cancer G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6350648ce43b56eb0bf92e38f3badc0d
https://doi.org/10.1038/nature13438
https://doi.org/10.1038/nature13438
Autor:
J. Silvio Gutkind, Amber N. Stratman, Brigid D. Lo, Brant M. Weinstein, Constantinos M. Mikelis, Kameha R. Kidd, Makoto Kamei, Weijun Pan, George E. Davis, Kenna M. Shaw, Daniel Castranova, Van N. Pham, Jesús Torres-Vázquez
Publikováno v:
Blood. 120:489-498
Understanding the mechanisms that regulate angiogenesis and translating these into effective therapies are of enormous scientific and clinical interests. In this report, we demonstrate the central role of CDP-diacylglycerol synthetase (CDS) in the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424138d547d7fe2d826ae3008f5fc13e
https://doi.org/10.1182/blood-2012-02-408328
https://doi.org/10.1182/blood-2012-02-408328
Autor:
Makoto Kamei, Benjamin L. Martin, Daniel Castranova, David W. Raible, Brant M. Weinstein, Evelyn Véliz, Sean Trzaska, Jesús Torres-Vázquez, Van N. Pham, Jorge Carretero-Ortega, Florian Ulrich, Eva Lancaster, Andrew Prendergast, Javier Menéndez, Kameha R. Kidd, Kenna M. Shaw, Carlos Narvaez, Belinda Sun, Brigid D. Lo, Valerie Pershad
Publikováno v:
Development (Cambridge, England)
The cerebral vasculature provides the massive blood supply that the brain needs to grow and survive. By acquiring distinctive cellular and molecular characteristics it becomes the blood-brain barrier (BBB), a selectively permeable and protective inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c722ae708ae799f09461a7ed4e69f418
https://doi.org/10.1242/dev.123059
https://doi.org/10.1242/dev.123059
Autor:
Kameha R. Kidd, Van N. Pham, Alexander Ruby, Makoto Kamei, Daniel Castranova, Brigid D. Lo, Brant M. Weinstein, Kenna M. Shaw, Jesus Torres-Vasquez
Publikováno v:
Developmental Dynamics. 235:1753-1760
We identified four mutants in two distinct loci exhibiting similar trunk vascular patterning defects in an F3 genetic screen for zebrafish vascular mutants. Initial vasculogenesis is not affected in these mutants, with proper specification and differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c290886ae1269062586ee8ef3046b6c
https://doi.org/10.1002/dvdy.20814
https://doi.org/10.1002/dvdy.20814
Autor:
Viviana E Gallardo, Abdel G. Elkahloun, Shawn M. Burgess, Aranza I. Torrado, Lisha Xu, Jennifer Idol, Chie Satou, Shin-ichi Higashijima, Brant M. Weinstein, John Bradsher, Kenna M. Shaw, Martine Behra, Jessica Sheehy, Seth Zonies
Publikováno v:
BMC Developmental Biology
BMC Developmental Biology, Vol 12, Iss 1, p 6 (2012)
BMC Developmental Biology, Vol 12, Iss 1, p 6 (2012)
Background Because of the structural and molecular similarities between the two systems, the lateral line, a fish and amphibian specific sensory organ, has been widely used in zebrafish as a model to study the development/biology of neuroepithelia of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2b5810bde2e83fd395ecdc05726525
https://pubmed.ncbi.nlm.nih.gov/22273551
https://pubmed.ncbi.nlm.nih.gov/22273551
Autor:
Kenna M. Shaw
Publikováno v:
The American Journal of Human Genetics. 78(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1913388a500923333c504a4306f29579