Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kenn Zwaan"'
Autor:
Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Mohammad Arkani, Edward Post, Sjors G. J. G. In ‘t Veld, Jip Ramaker, Kenn Zwaan, Ece Demirel Kucukguzel, Laurine E. Wedekind, Arjan W. Griffioen, Mirjam Oude Egbrink, Marijke J. E. Kuijpers, Daan van den Broek, David P. Noske, Koen J. Hartemink, Siamack Sabrkhany, Idris Bahce, Nik Sol, Harm-Jan Bogaard, Danijela Koppers-Lalic, Myron G. Best, Thomas Wurdinger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Liquid biopsy approaches offer a promising technology for early and minimally invasive cancer detection. Tumor-educated platelets (TEPs) have emerged as a promising liquid biopsy biosource for the detection of various cancer types. In this s
Externí odkaz:
https://doaj.org/article/9358e61d08a441cdb79204397fabd108
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
Purpose:Diffuse intrinsic pontine glioma (DIPG) is an incurable type of pediatric brain cancer, which in the majority of cases is driven by mutations in genes encoding histone 3 (H3K27M). We here determined the preclinical therapeutic potential of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426e325eb37e62297bb71b9385084f22
https://doi.org/10.1158/1078-0432.c.6529571
https://doi.org/10.1158/1078-0432.c.6529571
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
Legends pertaining to supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f3f0b188d7068471497ed95dac109a
https://doi.org/10.1158/1078-0432.22477094
https://doi.org/10.1158/1078-0432.22477094
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
File containing all supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081cd3246c4a6479a7a296a32247511d
https://doi.org/10.1158/1078-0432.22477091
https://doi.org/10.1158/1078-0432.22477091
Autor:
Esther Hulleman, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Olaf van Tellingen, Timothy N. Phoenix, Marianna Bugiani, Ángel Montero Carcaboso, Eric H. Raabe, Rintaro Hashizume, Jan Koster, Jos W.R. Twisk, Laurine E. Wedekind, Tonny Lagerweij, Levi C.M. Buil, Marjolein Breur, Piotr Waranecki, Kenn Zwaan, A. Charlotte P. Sewing, Dennis S. Metselaar, Mark C. de Gooijer, Michaël H. Meel
Sequences of shRNA constructs used in the present study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0487d8a1c4c34ee702f686689b68552b
https://doi.org/10.1158/1078-0432.22477088.v1
https://doi.org/10.1158/1078-0432.22477088.v1
Autor:
A. Josien Smits, Mohammad Arkani, Sjors G.J.G. In ’t Veld, Anna E. Huis in ‘t Veld, Nik Sol, Joanne A. Groeneveldt, Liza Botros, Natalia J. Braams, Samara M.A. Jansen, Jip Ramaker, Kenn Zwaan, Edward Post, Esther J. Nossent, Anco Boonstra, Frances S. de Man, Anton Vonk Noordegraaf, Jose Gomez-Arroyo, Myron G. Best, Tom Wurdinger, Harm Jan Bogaard
Publikováno v:
Annals of the American Thoracic Society, 19(10), 1650-1660. American Thoracic Society
Smits, A J, Arkani, M, In 't Veld, S G J G, Huis In 't Veld, A E, Sol, N, Groeneveldt, J A, Botros, L, Braams, N J, Jansen, S M, Ramaker, J, Zwaan, K, Post, E, Nossent, E J, Boonstra, A, de Man, F S, Vonk Noordegraaf, A, Gomez-Arroyo, J, Best, M G, Wurdinger, T & Bogaard, H J 2022, ' Distinct Platelet Ribonucleic Acid Signatures in Patients with Pulmonary Hypertension ', Annals of the American Thoracic Society, vol. 19, no. 10, pp. 1650-1660 . https://doi.org/10.1513/AnnalsATS.202201-085OC
Smits, A J, Arkani, M, In 't Veld, S G J G, Huis In 't Veld, A E, Sol, N, Groeneveldt, J A, Botros, L, Braams, N J, Jansen, S M, Ramaker, J, Zwaan, K, Post, E, Nossent, E J, Boonstra, A, de Man, F S, Vonk Noordegraaf, A, Gomez-Arroyo, J, Best, M G, Wurdinger, T & Bogaard, H J 2022, ' Distinct Platelet Ribonucleic Acid Signatures in Patients with Pulmonary Hypertension ', Annals of the American Thoracic Society, vol. 19, no. 10, pp. 1650-1660 . https://doi.org/10.1513/AnnalsATS.202201-085OC
Rationale: Pulmonary hypertension encompasses progressive disorders leading to right ventricular dysfunction and early death. Late detection is an important cause of poor clinical outcomes. However, biomarkers that accurately predict the presence of
Autor:
Angel M. Carcaboso, Timothy N. Phoenix, Dennis S. Metselaar, Tonny Lagerweij, Esther Hulleman, Laurine E. Wedekind, Jos W. R. Twisk, Dannis G. van Vuurden, Jan Koster, Gertjan J.L. Kaspers, Olaf van Tellingen, Kenn Zwaan, Piotr Waranecki, Eric H. Raabe, Michaël H. Meel, Rintaro Hashizume, A. Charlotte P. Sewing, Mark C. de Gooijer, Marjolein Breur, Marianna Bugiani, Levi C.M. Buil
Publikováno v:
CLINICAL CANCER RESEARCH
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Clinical cancer research, 26(13), 3319-3332. American Association for Cancer Research Inc.
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Meel, M H, de Gooijer, M C, Metselaar, D S, Sewing, A C P, Zwaan, K, Waranecki, P, Breur, M, Buil, L C M, Lagerweij, T, Wedekind, L E, Twisk, J W R, Koster, J, Hashizume, R, Raabe, E H, Montero Carcaboso, Á, Bugiani, M, Phoenix, T N, van Tellingen, O, van Vuurden, D G, Kaspers, G J L & Hulleman, E 2020, ' Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 26, no. 13, pp. 3319-3332 . https://doi.org/10.1158/1078-0432.CCR-19-3538
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(13), 3319-3332. American Association for Cancer Research Inc.
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Clinical cancer research, 26(13), 3319-3332. American Association for Cancer Research Inc.
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Meel, M H, de Gooijer, M C, Metselaar, D S, Sewing, A C P, Zwaan, K, Waranecki, P, Breur, M, Buil, L C M, Lagerweij, T, Wedekind, L E, Twisk, J W R, Koster, J, Hashizume, R, Raabe, E H, Montero Carcaboso, Á, Bugiani, M, Phoenix, T N, van Tellingen, O, van Vuurden, D G, Kaspers, G J L & Hulleman, E 2020, ' Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 26, no. 13, pp. 3319-3332 . https://doi.org/10.1158/1078-0432.CCR-19-3538
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(13), 3319-3332. American Association for Cancer Research Inc.
Purpose: Diffuse intrinsic pontine glioma (DIPG) is an incurable type of pediatric brain cancer, which in the majority of cases is driven by mutations in genes encoding histone 3 (H3K27M). We here determined the preclinical therapeutic potential of c
Autor:
François Rustenburg, Cyra E. Leurs, Bakhos A. Tannous, Maud Tjerkstra, Farrah J. Mateen, Sander Idema, Bauke Ylstra, W. Peter Vandertop, Laurine E. Wedekind, Nik Sol, Adrienne Vancura, Edward Post, William P.J. Leenders, R. Jonas A. Nilsson, B. Moraal, Jip Ramaker, Anna C. Navis, Kenn Zwaan, Ann Hoeben, Sjors G J G In 't Veld, Jihane Tannous, Joep Killestein, Philip C. De Witt Hamer, Jaap C. Reijneveld, Thomas Wurdinger, Heleen Verschueren, Pieter Wesseling, Pepijn Schellen, David P. Noske, Myron G. Best
Publikováno v:
Cell Reports Medicine, 1(7):100101. Cell Press
Cell reports. Medicine, 1(7):100101. Cell Press
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101-(2020)
Cell Reports Medicine, 1, 7
Cell Reports. Medicine
Cell Reports Medicine, 1
Sol, N, in ‘t Veld, S G J G, Vancura, A, Tjerkstra, M, Leurs, C, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Zwaan, K, Ramaker, J, Wedekind, L E, Tannous, J, Ylstra, B, Killestein, J, Mateen, F, Idema, S, de Witt Hamer, P C, Navis, A C, Leenders, W P J, Hoeben, A, Moraal, B, Noske, D P, Vandertop, W P, Nilsson, R J A, Tannous, B A, Wesseling, P, Reijneveld, J C, Best, M G & Wurdinger, T 2020, ' Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma ', Cell reports. Medicine, vol. 1, no. 7, 100101, pp. 100101 . https://doi.org/10.1016/j.xcrm.2020.100101, https://doi.org/10.1016/j.xcrm.2020.100101
Cell reports. Medicine, 1(7):100101. Cell Press
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101-(2020)
Cell Reports Medicine, 1, 7
Cell Reports. Medicine
Cell Reports Medicine, 1
Sol, N, in ‘t Veld, S G J G, Vancura, A, Tjerkstra, M, Leurs, C, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Zwaan, K, Ramaker, J, Wedekind, L E, Tannous, J, Ylstra, B, Killestein, J, Mateen, F, Idema, S, de Witt Hamer, P C, Navis, A C, Leenders, W P J, Hoeben, A, Moraal, B, Noske, D P, Vandertop, W P, Nilsson, R J A, Tannous, B A, Wesseling, P, Reijneveld, J C, Best, M G & Wurdinger, T 2020, ' Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma ', Cell reports. Medicine, vol. 1, no. 7, 100101, pp. 100101 . https://doi.org/10.1016/j.xcrm.2020.100101, https://doi.org/10.1016/j.xcrm.2020.100101
Summary Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA prof
Autor:
Harm-Jan Bogaard, Frances S. de Man, Josien Smits, Kenn Zwaan, Mohammad Arkani, Sjors G J G In 't Veld, Anton Vonk Noordegraaf, Thomas Wurdinger, Myron G. Best, Samara M.A. Jansen, Edward Post, Jip Ramaker
Publikováno v:
Pulmonary hypertension.