Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Kenn Holmbeck"'
Autor:
Anna Offersgaard, Carlos R. Duarte Hernandez, Yuyong Zhou, Zhe Duan, Karen Anbro Gammeltoft, Katrine T. Hartmann, Ulrik Fahnøe, Pavel Marichal-Gallardo, Garazi Peña Alzua, Alexander P. Underwood, Christina Sølund, Nina Weis, Jesper Hansen Bonde, Jan P. Christensen, Gabriel K. Pedersen, Henrik Elvang Jensen, Kenn Holmbeck, Jens Bukh, Judith Margarete Gottwein
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Rapidly waning immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires continued global access to affordable vaccines. Globally, inactivated SARS-CoV-2 vaccines have been widely used during the SARS-CoV-2 pande
Externí odkaz:
https://doaj.org/article/7364ae58a77642cc80f00f3bfff1ca99
Autor:
Anna Offersgaard, Carlos Rene Duarte Hernandez, Shan Feng, Pavel Marichal-Gallardo, Kenn Holmbeck, Anne Finne Pihl, Carlota Fernandez-Antunez, Garazi Peña Alzua, Katrine Top Hartmann, Long V. Pham, Yuyong Zhou, Karen Anbro Gammeltoft, Ulrik Fahnøe, Uffe Vest Schneider, Gabriel Kristian Pedersen, Henrik Elvang Jensen, Jan Pravsgaard Christensen, Santseharay Ramirez, Jens Bukh, Judith Margarete Gottwein
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105949- (2023)
Summary: Vaccines have relieved the public health burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and globally inactivated vaccines are most widely used. However, poor vaccination accessibility and waning immunity maintain the
Externí odkaz:
https://doaj.org/article/5be313e70944483e85a0601f5bf5dfe3
Autor:
Luis Fernandez de Castro, Brian J. Sworder, Byron Mui, Kathryn Futrega, Agnes Berendsen, Matthew D. Phillips, Nathan J. Burbach, Natasha Cherman, Sergei Kuznetsov, Yankel Gabet, Kenn Holmbeck, Pamela G. Robey
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract In a previous transcriptomic study of human bone marrow stromal cells (BMSCs, also known as bone marrow-derived “mesenchymal stem cells”), SFRP2 was highly over-represented in a subset of multipotent BMSCs (skeletal stem cells, SSCs), wh
Externí odkaz:
https://doaj.org/article/01a82cd57e0d47c091b9d82673e78dcd
Autor:
Long V. Pham, Rodrigo Velázquez-Moctezuma, Ulrik Fahnøe, Laura Collignon, Priyanka Bajpai, Christina Sølund, Nina Weis, Kenn Holmbeck, Jannick Prentoe, Jens Bukh
Publikováno v:
Viruses, Vol 14, Iss 11, p 2527 (2022)
Hepatitis C virus (HCV) genotype 4 is highly prevalent in the Middle East and parts of Africa. Subtype 4d has recently spread among high-risk groups in Europe. However, 4d infectious culture systems are not available, hampering studies of drugs, as w
Externí odkaz:
https://doaj.org/article/a1d9cda048864f47943b04977b05abfb
Autor:
Daniel H Madsen, Henrik J Jürgensen, Signe Ingvarsen, Maria C Melander, Reidar Albrechtsen, Andreas Hald, Kenn Holmbeck, Thomas H Bugge, Niels Behrendt, Lars H Engelholm
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71261 (2013)
A well-coordinated remodeling of uncalcified collagen matrices is a pre-requisite for bone development and homeostasis. Collagen turnover proceeds through different pathways, either involving extracellular reactions exclusively, or being dependent on
Externí odkaz:
https://doaj.org/article/40e8c086b0fb4c2a89a940269289a9b0
Autor:
Raphael Wolfisberg, Kenn Holmbeck, Eva Billerbeck, Caroline E. Thorselius, Mariana N. Batista, Ulrik Fahnøe, Emma A. Lundsgaard, Matthew J. Kennedy, Louise Nielsen, Charles M. Rice, Jens Bukh, Troels K. H. Scheel
Publikováno v:
Journal of Virology. 97
A prophylactic vaccine is required to achieve the World Health Organization’s objective for hepatitis C virus elimination as a serious public health threat. However, the lack of robust immunocompetent animal models supporting hepatitis C virus infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3114c3aec15d2f2f4562ebeb60c1f1d
https://doi.org/10.1128/jvi.01812-22
https://doi.org/10.1128/jvi.01812-22
Autor:
Sergey Leikin, Hideaki Nagase, Robert Visse, Charlotte L. Phillips, Kenn Holmbeck, Dan L. Sackett, Juan Carlos Vera, Sejin Han, Elena Makareeva
Supplementary Figures 1-6 from Carcinomas Contain a Matrix Metalloproteinase–Resistant Isoform of Type I Collagen Exerting Selective Support to Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24997f54363f1b3cb0b4dd88dc191a46
https://doi.org/10.1158/0008-5472.22382391.v1
https://doi.org/10.1158/0008-5472.22382391.v1
Autor:
Sergey Leikin, Hideaki Nagase, Robert Visse, Charlotte L. Phillips, Kenn Holmbeck, Dan L. Sackett, Juan Carlos Vera, Sejin Han, Elena Makareeva
Collagen fibers affect metastasis in two opposing ways, by supporting invasive cells but also by generating a barrier to invasion. We hypothesized that these functions might be performed by different isoforms of type I collagen. Carcinomas are report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343e4d152113a793c1ff07da08de7e5a
https://doi.org/10.1158/0008-5472.c.6500187
https://doi.org/10.1158/0008-5472.c.6500187
Autor:
Sergey Leikin, Hideaki Nagase, Robert Visse, Charlotte L. Phillips, Kenn Holmbeck, Dan L. Sackett, Juan Carlos Vera, Sejin Han, Elena Makareeva
Supplementary Table 1 from Carcinomas Contain a Matrix Metalloproteinase–Resistant Isoform of Type I Collagen Exerting Selective Support to Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df6a923ea84de906d6bf462db1274d5
https://doi.org/10.1158/0008-5472.22382388
https://doi.org/10.1158/0008-5472.22382388
Autor:
Raphael Wolfisberg, Caroline E. Thorselius, Eduardo Salinas, Elizabeth Elrod, Sheetal Trivedi, Louise Nielsen, Ulrik Fahnøe, Amit Kapoor, Arash Grakoui, Charles M. Rice, Jens Bukh, Kenn Holmbeck, Troels K. H. Scheel
Publikováno v:
Wolfisberg, R, Thorselius, C E, Salinas, E, Elrod, E, Trivedi, S, Nielsen, L, Fahnøe, U, Kapoor, A, Grakoui, A, Rice, C M, Bukh, J, Holmbeck, K & Scheel, T K H 2022, ' Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV ', Hepatology, vol. 76, no. 5, pp. 1506-1519 . https://doi.org/10.1002/hep.32535
Background and Aims: Lack of tractable immunocompetent animal models amenable to robust experimental challenge impedes vaccine efforts for HCV. Infection with rodent hepacivirus from Rattus norvegicus (RHV-rn1) in rats shares HCV-defining characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08bbb0d5ec256bcbe15c25b67f4a2b0
https://doi.org/10.1002/hep.32535
https://doi.org/10.1002/hep.32535