Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kenju Miura"'
Autor:
Atsuto Ogata, Takashi Nakatsuka, Hidenobu Murafuji, Kumiko Kadoshima-Yamaoka, Yoshiaki Fukuda, Kenji Chamoto, Kazuhiro Nagahira, Hidekazu Inoue, Yasuhiro Hayashi, Masao Murakawa, Asako Nagahira, Yoshitaka Tanaka, Takashi Nishimura, Kenju Miura, Satomi Kanki, Megumi Goto
Publikováno v:
International Immunopharmacology. 9:1347-1351
An intravenous injection of Concanavalin A (Con A) elevated the serum level of alanine aminotransferase (ALT) activity, a marker for liver damage, and an oral administration of PDE7A inhibitor SUN11817 suppressed the increase of ALT activity in a dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0794096455cf40766e65dda48885cc3b
https://doi.org/10.1016/j.intimp.2009.08.002
https://doi.org/10.1016/j.intimp.2009.08.002
Autor:
Hidekazu Inoue, Yasuhiro Hayashi, Yoshitaka Tanaka, Kumiko Kadoshima-Yamaoka, Hidenobu Murafuji, Yoshiaki Fukuda, Masao Murakawa, Takashi Nishimura, Kenji Chamoto, Kenju Miura, Megumi Goto, Takashi Nakatsuka, Kazuhiro Nagahira
Publikováno v:
Cellular Immunology. 258:147-151
A possible involvement of phosphodiesterase 7A (PDE7A) in proliferation and function of NKT cells was examined using ASB16165, a selective inhibitor for PDE7A. Stimulation of isolated murine NKT cells with anti-CD3 antibody plus IL-2 induced not only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22006aad43428471e967f70eab280bf4
https://doi.org/10.1016/j.cellimm.2009.04.005
https://doi.org/10.1016/j.cellimm.2009.04.005
Publikováno v:
International Archives of Allergy and Immunology. 128:235-239
Background: Chymase is a chymotrypsin-like serine protease primarily stored in mast cells. Infection with helminth parasites is known to increase the level of mast cell chymase in the jejunum and serum in mice. The aim of the present study is to eluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3447bc640c80be15c2934f4538d86b
https://doi.org/10.1159/000064257
https://doi.org/10.1159/000064257
Autor:
Koichi Nishigaki, Anupom Mondal, Sayaka Yoshida, Makoto Koyama, Ichiro Sakata, Kazuya Nishina, Takafumi Sakai, Naoto Nemoto, Shingo Ueno, Kenju Miura, Yujiro Hayashi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(28)
G protein-coupled receptors (GPCRs) are major drug targets, and their ligands are currently being explored and developed by many pharmaceutical companies and independent researchers. Class A (rhodopsin-like) GPCRs compose a predominant GPCR family; t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88e3ba88a539131057bda9e328aec62
https://pubmed.ncbi.nlm.nih.gov/22723348
https://pubmed.ncbi.nlm.nih.gov/22723348
Autor:
Kenji Chamoto, Yoshiaki Fukuda, Takashi Nakatsuka, Asako Nagahira, Takashi Nishimura, Yasuhiro Hayashi, Masao Murakawa, Yoshitaka Tanaka, Kenju Miura, Kazuhiro Nagahira, Kumiko Kadoshima-Yamaoka, Megumi Goto, Hidenobu Murafuji, Hidekazu Inoue
Publikováno v:
Immunology letters. 122(2)
Phosphodiesterase 7A (PDE7A) has been suggested to be involved in activation of T lymphocytes. In the present study, a possible involvement of PDE7A in function of preactivated T cells (i.e. T lymphoblasts) was investigated using ASB16165, an inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddf0e69b0a431bdc98d4420085c3d1e
https://pubmed.ncbi.nlm.nih.gov/19195485
https://pubmed.ncbi.nlm.nih.gov/19195485
Autor:
Megumi Goto, Takashi Nakatsuka, Kenji Chamoto, Yoshiaki Fukuda, Hidenobu Murafuji, Hidekazu Inoue, Kumiko Kadoshima-Yamaoka, Masao Murakawa, Yasuhiro Hayashi, Kenju Miura, Kazuhiro Nagahira, Yoshitaka Tanaka, Takashi Nishimura
Publikováno v:
International immunopharmacology. 9(1)
In the present study, possible role of phosphodiesterase 7 (PDE7) in development and function of cytotoxic T lymphocyte (CTL) was examined using ASB16165, a specific inhibitor for PDE7. ASB16165 inhibited generation of CTL activity in mixed lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6964449c62a39be2251f2c036c2fa8b3
https://pubmed.ncbi.nlm.nih.gov/18992850
https://pubmed.ncbi.nlm.nih.gov/18992850
Autor:
Toshiharu Nakajima, Kenji Matsumoto, Shuhei Fukuda, Maki Terakawa, Kenju Miura, Hirohisa Saito
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 172(4)
Apoptosis is an important cellular mechanism for controlling cell viability and proliferation. With respect to eosinophils, cytokines prolong their survival, whereas corticosteroids reduce their survival in vitro. CD30, a member of the TNFR family, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44d5f19948cb4a5a9a09476cf5029a8
https://pubmed.ncbi.nlm.nih.gov/14764685
https://pubmed.ncbi.nlm.nih.gov/14764685
Publikováno v:
International archives of allergy and immunology. 128(3)
Chymase is a chymotrypsin-like serine protease primarily stored in mast cells. Infection with helminth parasites is known to increase the level of mast cell chymase in the jejunum and serum in mice. The aim of the present study is to elucidate the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b2ebbe559c9588c37c2d732e67f5c59
https://pubmed.ncbi.nlm.nih.gov/12119506
https://pubmed.ncbi.nlm.nih.gov/12119506
Autor:
Kenju Miura, Naohiro Watanabe, Masaoki Tsudzuki, Yoshiaki Fukuda, Adumi Wada, Yoshiaki Tomimori, Kayo Saito
Publikováno v:
International archives of allergy and immunology. 128(3)
Background: Mast cell chymase is thought to participate in allergic inflammation, but its precise role remains undetermined. Inbred NC/Nga mice develop skin lesions similar to atopic dermatitis (AD) when they grow up in a conventional environment. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc0862c65d8770fcf680ae2ed7e64b6
https://pubmed.ncbi.nlm.nih.gov/12119505
https://pubmed.ncbi.nlm.nih.gov/12119505
Autor:
Toshihiro Nakanishi, Masafumi Tsujimoto, Junko Hashino, Mayumi Adachi, Naruto Katsuragi, Nobuo Tsuruoka, Tomohiro Rogi, Toyoko Katayama, Munetada Haruyama, Nozomi Yamaguchi, Masanao Teramura, Kenju Miura, Hiroshi Nakazato, Fuyuki Iwasa, Hideaki Mizoguchi, Shiho Kodama, Kyoko Yamashiro, Kozo Yamaichi, Nobuhiro Ishida, Masahiro Nakao, Tatsuya Kurihara
Publikováno v:
The Journal of biological chemistry. 272(24)
A new member of the serine protease inhibitor (serpin) superfamily with megakaryocyte maturation activity was purified, and its cDNA was cloned and characterized. The predicted amino acid sequence consisting of 380 residues was unique and was 38% ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9054e06993b19942bae6aac21ecb772
https://pubmed.ncbi.nlm.nih.gov/9182567
https://pubmed.ncbi.nlm.nih.gov/9182567