Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Kenjiro Tanoue"'
Autor:
Hidemi Kajimoto, Kagari Murasaki, Kenjiro Tanoue, Yoshiki Mori, Makoto Nakazawa, Hiroshi Kasanuki, Toshio Nakanishi
Publikováno v:
Circulation Journal. 71:948-953
Background The basic mechanisms of thromboembolism in cyanotic congenital heart disease (CCHD) have not been well clarified. P-selectin on the platelets reflects platelet activation. Thrombomodulin is a critical cofactor for thrombin-mediated activat
Publikováno v:
Journal of Electron Microscopy. 52:183-195
We employed a double-staining method to immunocytochemically study the role of alpha-granule membrane alphaIIbbeta3 integrin in the expression of intragranular fibrinogen (Fbg) and albumin on the surface of thrombin-activated human platelets. In unst
Autor:
Masato Umeda, Takaomi C. Saido, Noriko Akamatsu, Atsumi Yamaguchi, Kenjiro Tanoue, Naomasa Yamamoto, Mizuho Kaneda
Publikováno v:
Thrombosis Research. 97:317-326
CD36, a multifunctional adhesive receptor on a variety of cells such as monocytes and platelets, has been implicated in clearance of modified LDL and in the removal of apoptotic or senescent cells. We recently developed a new anti-CD36 monoclonal ant
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 11:542-549
Publikováno v:
British Journal of Haematology. 104:55-63
We have studied down-regulation and redistribution of glycoprotein V (GPV) and its fragment GPVf2, a subunit of a receptor for von Willebrand factor (VWF), on the surface membrane of thrombin and thrombin receptor activating peptide (TRAP) stimulated
Autor:
Kenjiro Tanoue, Ryoichi Kase, Masaharu Kotani, Tomomasa Oguchi, Naomasa Yamamoto, Yasuhiro Katagiri, Kohji Itoh, Hitoshi Sakuraba, Kouichi Utsumi, Michie Shimmoto, Takashi Ozawa
Publikováno v:
Clinica Chimica Acta. 279:55-68
A renal disorder is one of the important manifestations of Fabry disease, but the details of the pathogenesis have not been clarified yet. We examined the possibility that the vitronectin receptor (VNR, integrin alpha V beta 3), one of the integrins,
Autor:
Shigenori Honda, Yoshiaki Tomiyama, Masamichi Shiraga, Yoshiyuki Kurata, Seiji Tadokoro, Yuji Matsuzawa, Yuzuru Kanakura, Kenjiro Tanoue, Hidenori Suzuki, Satoru Kosugi
Publikováno v:
Blood. 92:3710-3720
The platelet integrin IIbβ3 has become a new target for the treatment of pathological thrombosis. It becomes apparent that the affinity of IIbβ3 for its ligands is dynamically regulated by inside-out signaling. However, the components that co
Autor:
Yasuhiro Katagiri, Masato Umeda, Naomasa Yamamoto, Morio Arai, Keizo Inoue, Kenjiro Tanoue, Shigeru Tokita, Koji Igarashi
Publikováno v:
Thrombosis and Haemostasis. 75:168-174
SummaryTo study the pathological functions of anti-phospholipid (anti-PL) antibodies, we have analyzed their effect on platelet function. We identified an IgG anti-PL mAb, designated PSG3, which cross-reacted specifically with glycoprotein (GP) IIIa
Publikováno v:
Platelets. 6:204-208
Human melanoma cell Line, HMV-I, has been shown to induce platelet aggregation without thrombin generation. The platelet-aggregating activity of HMV-I cells increased with increasing culture periods of the cells. However, data indicate that the plate
Autor:
Toshiro Takafuta, Kenjiro Tanoue, T Fujimoto, Morio Arai, Naomasa Yamamoto, Kingo Fujimura, Akira Suehiro, Eizo Kakishita, Masaaki Noda, Atsushi Kuramoto, Takeshi Shimomura, A. Shimasaki
Publikováno v:
Thrombosis and Haemostasis. 74:1411-1415
SummaryBernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder, which is caused by deficiency or decrease of the platelet GPIb/IX/V complex. Analysis of two patients with BSS by How cytometry of the blood revealed different expression pa