Zobrazeno 1 - 10
of 681
pro vyhledávání: '"Kenjiro KIMURA"'
Autor:
Masanori Ozaki, Ken Kageyama, Kenjiro Kimura, Shinpei Eguchi, Akira Yamamoto, Ryota Tanaka, Takehito Nota, Hiroki Yonezawa, Hideyuki Nishiofuku, Yuki Sakai, Naoki Tani, Atsushi Jogo, Mizue Terai, Takami Sato, Takeaki Ishizawa, Yukio Miki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Liver metastases from pancreatic ductal adenocarcinoma (PDAC) are highly fatal. A rat-based patient-derived tumor xenograft (PDX) model is available for transcatheter therapy. This study aimed to create an immunodeficient rat model with live
Externí odkaz:
https://doaj.org/article/a062ad6132a74f5f94005ead20d308ed
Autor:
Ken‐ichi Okada, Kenjiro Kimura, Yo‐Ichi Yamashita, Kazuto Shibuya, Ippei Matsumoto, Sohei Satoi, Kazuhiro Yoshida, Yasuhiro Kodera, Takahiro Akahori, Seiko Hirono, Hidetoshi Eguchi, Mitsuhiro Asakuma, Masaji Tani, Etsuro Hatano, Hisashi Ikoma, Go Ohira, Hiromitsu Hayashi, Ke Wan, Toshio Shimokawa, Manabu Kawai, Hiroki Yamaue, The NAC‐GA investigators
Publikováno v:
Annals of Gastroenterological Surgery, Vol 7, Iss 6, Pp 997-1008 (2023)
Abstract Background Nab‐paclitaxel plus gemcitabine is a standard treatment for metastatic/locally advanced pancreatic cancer. The effectiveness of neoadjuvant therapy with nab‐paclitaxel plus gemcitabine (GnP‐NAT) in patients with borderline r
Externí odkaz:
https://doaj.org/article/86604cdf338e458589ae44c27f7b2e8a
Autor:
Hitoshi Kotake, Yuji Ogura, Shohei Yamada, Kazuho Inoue, Shiika Watanabe, Daisuke Ichikawa, Takeshi Sugaya, Keiichi Ohata, Yasunori Natsuki, Seiko Hoshino, Minoru Watanabe, Kenjiro Kimura, Yugo Shibagaki, Atsuko Kamijo-Ikemori
Publikováno v:
Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-14 (2023)
Abstract We previously reported the significant increase in limb muscle strength and cross-sectional area of the type IIb muscle fibers in the extensor digitorum longus (EDL) muscle in a type 2 diabetic animal model, with Spontaneously Diabetic Torii
Externí odkaz:
https://doaj.org/article/23f1e23b899f41a9b01a07478fb467ce
Autor:
Suguru Takayama, Kazuho Inoue, Yuji Ogura, Seiko Hoshino, Takeshi Sugaya, Keiichi Ohata, Hitoshi Kotake, Daisuke Ichikawa, Minoru Watanabe, Kenjiro Kimura, Yugo Shibagaki, Atsuko Kamijo-Ikemori
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The study aim was to determine if suppressed activation of angiotensin II type 1 receptor (AT1) prevents severe muscle atrophy after denervation. The sciatic nerves in right and left inferior limbs were cut in AT1a knockout homo (AT1a−/−
Externí odkaz:
https://doaj.org/article/302eda8b533b4257b9fde85f7359276c
Autor:
Ryota Tanaka, Kenjiro Kimura, Shimpei Eguchi, Go Ohira, Shogo Tanaka, Ryosuke Amano, Hiroaki Tanaka, Masakazu Yashiro, Masaichi Ohira, Shoji Kubo
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Cancer-associated fibroblasts (CAFs) play an important role in cancer growth by interacting with cancer cells, but their effects differ depending on the type of cancer. This study investigated the role of CAFs in biliary tract can
Externí odkaz:
https://doaj.org/article/2e5e73dfab134a8593d3fa5f589a3b16
Autor:
Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Kenjiro Kimura, Daisuke Oikawa, Yoshihiro Ikura, Ninh Quoc Dat, Truong Huu Hoang, Misako Sato-Matsubara, Minh Phuong Dong, Ngo Vinh Hanh, Sawako Uchida-Kobayashi, Fuminori Tokunaga, Shoji Kubo, Naoko Ohtani, Katsutoshi Yoshizato, Norifumi Kawada
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer development, is expressed in pericytes of all organs. Here, we examined the role of CY
Externí odkaz:
https://doaj.org/article/cd03332a8f1a4b8a91e1f4acb0f2336f
Autor:
Kazuho Inoue, Shohei Yamada, Seiko Hoshino, Minoru Watanabe, Kenjiro Kimura, Atsuko Kamijo-Ikemori
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background This study aims to investigate the effect of the glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) liraglutide on retinal pathological findings as compared with insulin and hydralazine using an animal model of type 2 diab
Externí odkaz:
https://doaj.org/article/2b22399397f647be88c5f9a5f1bd72fa
Autor:
Hiroshi Kataoka, Toshio Mochizuki, Mamiko Ohara, Yuki Tsuruta, Naomi Iwasa, Rie Yoshida, Ken Tsuchiya, Kosaku Nitta, Kenjiro Kimura, Tatsuo Hosoya, the FEATHER Investigators
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Attribute-based medicine is essential for patient-centered medicine. To date, the groups of patients with chronic kidney disease (CKD) requiring urate-lowering therapy are clinically unknown. Herein, we evaluated the efficacy of febuxostat u
Externí odkaz:
https://doaj.org/article/7159db7f584040c3bbba6912f9399014
Autor:
Atsushi Ishihara, Shogo Tanaka, Hiroji Shinkawa, Hisako Yoshida, Shigekazu Takemura, Ryosuke Amano, Kenjiro Kimura, Go Ohira, Kohei Nishio, Shoji Kubo
Publikováno v:
Annals of Gastroenterological Surgery, Vol 6, Iss 1, Pp 135-148 (2022)
Abstract Aim This study aimed to elucidate the effects of laparoscopic liver resection (LLR) vs open liver resection (OLR) for major complications (Clavien‐Dindo classification grade ≥ IIIa) in obese individuals with hepatocellular carcinoma (HCC
Externí odkaz:
https://doaj.org/article/2bd90aa6226149f89e563019a504cffa
Autor:
Masahiko Kinoshita, Akishige Kanazawa, Shogo Tanaka, Shigekazu Takemura, Ryosuke Amano, Kenjiro Kimura, Hiroji Shinkawa, Go Ohira, Kohei Nishio, Shoji Kubo
Publikováno v:
Annals of Gastroenterological Surgery, Vol 6, Iss 1, Pp 119-126 (2022)
Abstract Aim This study aimed to evaluate the indications of laparoscopic repeat liver resection (LRLR) for recurrent hepatocellular carcinoma from the viewpoint of its difficulty. Methods One hundred and one patients who underwent LRLR and 59 patien
Externí odkaz:
https://doaj.org/article/050ecb9e078e4d5fa3d7ef26b890f4c5