Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Kenjiro Hattori"'
Autor:
Kei Nakai, Nobuyoshi Fukumitsu, Teruhito Aihara, Hitoshi Ishikawa, Taishi Higashi, Hiroaki Kumada, Hidetoshi Arima, Keiichi Motoyama, Hideyuki Sakurai, Yoshitaka Matsumoto, Kenjiro Hattori
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 163
In this study, the tumor accumulation and antitumor effect of folate-modified cyclodextrin (ND201) purified with folate receptor (FR) connotated with BSH were examined. ND201 and BSH were stably bound in blood, and the mixing ratio 1:1 was most effic
Publikováno v:
Bioorganic & Medicinal Chemistry. 24(4):635-642
This paper describes the synthesis of a β-cyclodextrin (β-CyD) derivative conjugated with a C,C-glucopyranoside containing a benzene unit. Its doxorubicin-inclusion ability and structure are also discussed. SPR analysis revealed that the β-CyD con
Autor:
Keiichi Motoyama, Takahiro Koshigoe, Hidetoshi Arima, Risako Onodera, Taishi Higashi, Kenjiro Hattori, Ayaka Okamatsu, Tomoko Takeuchi, Yasutaka Shimada
Publikováno v:
Biomacromolecules. 14:4420-4428
We reported that per-6-folic acid (FA)-appended β-cyclodextrin (β-CyD) possessing two caproic acids between FA and a β-CyD molecule as a spacer (Fol-c2-β-CyD) could be useful as a promising antitumor drug carrier. However, the effects of the cavi
Autor:
Takahiro Koshigoe, Ayaka Okamatsu, Hidetoshi Arima, Taishi Higashi, Kenjiro Hattori, Risako Onodera, Keiichi Motoyama, Yasutaka Shimada, Tomoko Takeuchi
Publikováno v:
Bioconjugate Chemistry. 24:724-733
A large number of antitumor drug delivery carriers based on passive targeting and/or active targeting have been developed. However, encapsulation of antitumor drugs into these drug carriers is often complicated, and antitumor activities of these targ
Autor:
Ayumu Ohyama, Takuro Niidome, Haruna Ikeda, Yoshiki Katayama, Ayumi Yoshimatsu, Taishi Higashi, Kenjiro Hattori, Keiichi Motoyama, Hidetoshi Arima, Tomoko Takeuchi, Akira Tsuchiya
Publikováno v:
Molecular Pharmaceutics. 9:2591-2604
We previously reported that of the various polyamidoamine (PAMAM) STARBURST dendrimer (generation 3, G3) (dendrimer) conjugates with cyclodextrins (CyDs), the dendrimer (G3) conjugate with α-CyD having an average degree of substitution of 2.4 (α-CD
Publikováno v:
Transactions of the Materials Research Society of Japan. 35:809-812
Autor:
Takashi Yamanoi, Yoshiki Oda, Keiko Takahashi, Natsumi Kobayashi, Kenjiro Hattori, Kaname Katsuraya
Publikováno v:
Medicinal Chemistry. 4:244-255
Three kinds of β-cyclodextrin derivatives conjugated with glucose moieties, which were expected as models for a drug carrier targeting the drug delivery systems, were designed and synthesized from β-cyclodextrin and the natural product, 4-hydroxyph
Autor:
Ayumi Takanohashi, Mika Ogata, Katsuhiko Mikuni, Katsuyoshi Nakanishi, Kenjiro Hattori, Tomoko Takeuchi, Hideo Imata
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 57:339-342
We obtained the association constants Ka of estrogen (E2) and environmental chemicals by the surface plasmon resonance (SPR) assay using the immobilized mono-6-O-α-maltosyl-β-CD (G2βCD) compared with the immobilized β-CD and the immobilized estro
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 57:237-241
In order to develop a treatment method for industrial wastewater, the adsorption of 4-nonylphenol ethoxylates (NPEs), non-ionic surfactants used in the industry, onto chitosan beads having cyclodextrin (CDC beads) was investigated. Three kinds of CDC