Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Kenji TSUCHIHASHI"'
Autor:
Kenro Tanoue, Hirofumi Ohmura, Koki Uehara, Mamoru Ito, Kyoko Yamaguchi, Kenji Tsuchihashi, Yudai Shinohara, Peng Lu, Shingo Tamura, Hozumi Shimokawa, Taichi Isobe, Hiroshi Ariyama, Yoshihiro Shibata, Risa Tanaka, Hitoshi Kusaba, Taito Esaki, Kenji Mitsugi, Daisuke Kiyozawa, Takeshi Iwasaki, Hidetaka Yamamoto, Yoshinao Oda, Koichi Akashi, Eishi Baba
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Despite the success of immune checkpoint blockade (ICB) therapy for esophageal squamous cell cancer, the key immune cell populations that affect ICB efficacy remain unclear. Here, imaging mass cytometry of tumor tissues from ICB-treated pati
Externí odkaz:
https://doaj.org/article/02a8fed9a6414707bdd6b7834afbd8eb
Autor:
Kenji Tsuchihashi, Mamoru Ito, Shuji Arita, Hitoshi Kusaba, Wataru Kusano, Takashi Matsumura, Takafumi Kitazono, Shohei Ueno, Ryosuke Taguchi, Tomoyasu Yoshihiro, Yasuhiro Doi, Kohei Arimizu, Hirofumi Ohmura, Tatsuhiro Kajitani, Kenta Nio, Michitaka Nakano, Kotoe Oshima, Shingo Tamura, Tsuyoshi Shirakawa, Hozumi Shimokawa, Keita Uchino, Fumiyasu Hanamura, Yuta Okumura, Masato Komoda, Taichi Isobe, Hiroshi Ariyama, Taito Esaki, Kazuki Hashimoto, Noritaka Komune, Mioko Matsuo, Keiji Matsumoto, Kaori Asai, Tadamasa Yoshitake, Hidetaka Yamamoto, Yoshinao Oda, Koichi Akashi, Eishi Baba
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Rhabdomyosarcoma is the most common soft tissue sarcoma in children, but rare in adults. Para-meningeal rhabdomyosarcoma in head and neck (PM-HNRMS) is less applicable for surgery due to the anatomic reason. PM-HNRMS has a poor pr
Externí odkaz:
https://doaj.org/article/dd56a19bf0864e60aa13faa99e4c71cb
Autor:
Hirofumi Ohmura, Moe Kondo, Masato Uenomachi, Hiroshi Ariyama, Mamoru Ito, Kenji Tsuchihashi, Masahiro Ayano, Hiroaki Niiro, Koichi Akashi, Eishi Baba
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The anti-programmed cell death-1 (PD-1) antibody nivolumab has been shown to significantly prolong the survival of patients with unresectable advanced or recurrent gastric cancer (AGC). However, immune-related adverse events (irAEs), which show diffe
Externí odkaz:
https://doaj.org/article/64ec702a8066473396e5b1fb9e89851f
Autor:
Michio Nakamura, Taro Funakoshi, Shigeki Kataoka, Takahiro Horimatsu, Yoshitaka Nishikawa, Takeshi Matsubara, Takuro Mizukami, Tomoyuki Goto, Kenji Tsuchihashi, Eishi Baba, Takehiko Tsumura, Yoshiaki Mihara, Tetsuya Hamaguchi, Motoko Yanagita, Manabu Muto
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Monitoring proteinuria is important for the management of patients with cancer treated with anti-vascular endothelial growth factor (VEGF) or anti-VEGF receptor (VEGFR) inhibitors (VEGF/Ri). Here we investigated the difference bet
Externí odkaz:
https://doaj.org/article/c037f1bcec82452fbc6674c8c1730fe3
Autor:
Kenji Tsuchihashi, Kyoko Yamaguchi, Ryosuke Taguchi, Kenichi Kohashi, Kayo Ijichi, Yuta Okumura, Michitaka Nakano, Akari Ohno, Tomonobu Hioki, Hozumi Shimokawa, Hiroshi Ariyama, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 1, Pp 71-77 (2022)
Desmoid tumors are clonal fibroblastic neoplasms that arise in soft tissues. Patients with familial adenomatous polyposis (FAP) can develop intra-abdominal desmoid tumors. However, metachronous appearance of intra-abdominal desmoid tumor is rare, and
Externí odkaz:
https://doaj.org/article/b515dce10ffe4e12b996638509394845
Autor:
Kenji Tsuchihashi, Yuki Hirata, Juntaro Yamasaki, Kentaro Suina, Kenro Tanoue, Toshifumi Yae, Kenta Masuda, Eishi Baba, Koichi Akashi, Yuko Kitagawa, Hideyuki Saya, Osamu Nagano
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101246- (2022)
Epithelial-mesenchymal plasticity (EMP) refers to the reversible cellular transition between epithelial and mesenchymal status. Spontaneous EMP is also reported in breast and prostate cancer, leading to the acquisition of stem-cell properties and che
Externí odkaz:
https://doaj.org/article/5824d7a6d235432790144d73e187a66d
Autor:
Kenro Tanoue, Shingo Tamura, Hitoshi Kusaba, Yudai Shinohara, Mamoru Ito, Kenji Tsuchihashi, Tsuyoshi Shirakawa, Taiga Otsuka, Hirofumi Ohmura, Taichi Isobe, Hiroshi Ariyama, Sakuya Koreishi, Yuzo Matsushita, Hozumi Shimokawa, Risa Tanaka, Kenji Mitsugi, Koichi Akashi, Eishi Baba
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Although the neutrophil to lymphocyte ratio (NLR) was reported to be a predictive biomarker for clinical outcomes in various types of cancer, including recurrent or metastatic head and neck cancer (R/M HNSCC) treated with nivolumab, the usef
Externí odkaz:
https://doaj.org/article/089080158b5b4515bfcff8f5c0819000
Autor:
Hirofumi Ohmura, Mamoru Ito, Keita Uchino, Chihiro Okada, Shigeki Tanishima, Yuichi Yamada, Seiya Momosaki, Masato Komoda, Miyuki Kuwayama, Kyoko Yamaguchi, Yuta Okumura, Michitaka Nakano, Kenji Tsuchihashi, Taichi Isobe, Hiroshi Ariyama, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba
Publikováno v:
FEBS Open Bio, Vol 10, Iss 1, Pp 147-157 (2020)
Epstein–Barr virus (EBV)‐associated gastric cancer (GC) is associated with a high degree of DNA methylation. However, the association between chemotherapy susceptibility and tumor DNA methylation in advanced diseases remains unclear. The comprehe
Externí odkaz:
https://doaj.org/article/80d7b84ba5f14786b0a6e4b701c596bc
Autor:
Kyoko Yamaguchi, Mamoru Ito, Hirofumi Ohmura, Fumiyasu Hanamura, Michitaka Nakano, Kenji Tsuchihashi, Shuntaro Nagai, Hiroshi Ariyama, Hitoshi Kusaba, Hidetaka Yamamoto, Yoshinao Oda, Masafumi Nakamura, Koichi Akashi, Eishi Baba
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Tertiary lymphoid structures (TLSs), clusters of immune cells found around tumor tissue, have been shown to be associated with anti-tumor immunity, but the cellular composition within each TLS and whether the cellular composition of a TLS affects a p
Externí odkaz:
https://doaj.org/article/936c3ed61d5545fb8b4c923da3aef6a1
Autor:
Takakazu Higuchi, Fumio Omata, Kenji Tsuchihashi, Kazuhiko Higashioka, Ryosuke Koyamada, Sadamu Okada
Publikováno v:
Preventive Medicine Reports, Vol 4, Iss , Pp 417-422 (2016)
While cigarette smoking is a well-recognized cause of elevated white blood cell (WBC) count, studies on longitudinal effect of smoking cessation on WBC count are limited. We attempted to determine causal relationships between smoking and elevated WBC
Externí odkaz:
https://doaj.org/article/98648fd11073452085cf39929d4ac633