Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Kenji Soejima"'
Autor:
Isuru Induruwa, Carly Kempster, Patrick Thomas, Harriet McKinney, Jean-Daniel Malcor, Arkadiusz Bonna, Joana Batista, Kenji Soejima, Willem Ouwehand, Richard W. Farndale, Kate Downes, Masaaki Moroi, Stephanie M. Jung, Elizabeth A. Warburton
Publikováno v:
TH Open, Vol 07, Iss 04, Pp e294-e302 (2023)
Externí odkaz:
https://doaj.org/article/8ae6dcf47e944abfa2c75e9bcb37ce76
Autor:
Isuru Induruwa, Harriet McKinney, Carly Kempster, Patrick Thomas, Joana Batista, Jean-Daniel Malcor, Arkadiusz Bonna, Joanne McGee, Elaine Bumanlag-Amis, Karola Rehnstrom, Sophie Ashford, Kenji Soejima, Willem Ouwehand, Richard Farndale, Kate Downes, Elizabeth Warburton, Masaaki Moroi, Stephanie Jung
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262695 (2022)
ObjectivesPlatelet activation underpins thrombus formation in ischemic stroke. The active, dimeric form of platelet receptor glycoprotein (GP) VI plays key roles by binding platelet ligands collagen and fibrin, leading to platelet activation. We inve
Externí odkaz:
https://doaj.org/article/7102245d8cac49b2b1488e72c6a6c041
Autor:
Hideto Matsui, Maiko Takeda, Kenji Soejima, Yasunori Matsunari, Shogo Kasuda, Shiro Ono, Kenji Nishio, Midori Shima, Fumiaki Banno, Toshiyuki Miyata, Mitsuhiko Sugimoto
Publikováno v:
Haematologica, Vol 99, Iss 10 (2014)
Externí odkaz:
https://doaj.org/article/5515a8ecb9434eaba80c150a3d7cabbe
Autor:
Zuben E Sauna, Chinyere Okunji, Ryan C Hunt, Tanvi Gupta, Courtni E Allen, Elizabeth Plum, Adam Blaisdell, Vahan Grigoryan, S Geetha, Robert Fathke, Kenji Soejima, Chava Kimchi-Sarfaty
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6506 (2009)
BACKGROUND:The zinc metalloprotease ADAMTS13 is a multidomain protein that cleaves von Willebrand Factor (VWF) and is implicated in Thrombotic Thrombocytopenic Purpura (TTP) pathogenesis. Understanding the mechanism of this protein is an important go
Externí odkaz:
https://doaj.org/article/b97e435ff0124e57aef88ea631d1b582
Autor:
Katsunari Taguchi, Nobuchika Yamamoto, Toshihiro Nakashima, Hirofumi Higuchi, Fumihiko Sakai, Kenji Soejima, Masaharu Torikai, Daisuke Ishikawa, Hirotada Fujita
Publikováno v:
Journal of biochemistry. 168(3)
This study introduces a novel monoclonal anti-α9 integrin antibody (MA9-413) with human variable regions, isolated by phage display technology. MA9-413 specifically binds to both human and mouse α9 integrin by recognizing a conserved loop region de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ceb8a43ecff6361b05737609d958eb
https://pubmed.ncbi.nlm.nih.gov/32271918
https://pubmed.ncbi.nlm.nih.gov/32271918
Autor:
Koichiro Ueda, Ritsuko Seki, Mitsuo Miho, Takashi Okamura, Yoko Sogabe, Kenji Soejima, Yoko Matsuo, Yushiro Yamashita, Shuichi Ozono, Tatsuki Mizuochi, Shinichiro Nakagawa
Publikováno v:
The Kurume Medical Journal. 63:23-28
A 10-day-old male patient was referred to our hospital with severe umbilical bleeding. Prothrombin time (PT) and activated partial thromboplastin time (APTT) were prominently prolonged. Plasma coagulation factor X (FX) activity and antigen levels wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b9e95f167a78b2b38d4a890bf4b19d
https://doi.org/10.2739/kurumemedj.ms6300007
https://doi.org/10.2739/kurumemedj.ms6300007
Autor:
Masaki Hayakawa, Yuji Hori, Masanori Matsumoto, Yoshihiro Fujimura, Ayami Isonishi, Kenji Soejima
Publikováno v:
Transfusion. 53:3192-3202
Background Thrombotic thrombocytopenic purpura (TTP) is characterized by deficient ADAMTS13 activity. Treatment involves plasma exchange (PE). Both fresh-frozen plasma (FFP) and cryosupernatant (CSP) are used, but it remains to be determined which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53266bc0139b8a41ea2ba8b9ca3093ca
https://doi.org/10.1111/trf.12182
https://doi.org/10.1111/trf.12182
Autor:
Richard W. Farndale, Tomohiro Nakagaki, Stephanie M. Jung, Yoshiki Miura, Michael C. Berndt, Kenji Soejima, Joanna Marie Howes, Steve P. Watson, Nicholas Pugh, Dominique Bihan, Masaaki Moroi, Elizabeth E. Gardiner
Publikováno v:
The Journal of Biological Chemistry
Background: Platelet collagen receptor GPVI likely functions as a dimer rather than a monomer. Results: Preformed GPVI dimers, but not monomers, in resting platelets bind specific collagen sequences and are essential for platelet adhesion and activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e107400e28a2e826f31652eec76440c1
http://europepmc.org/articles/PMC3436176
http://europepmc.org/articles/PMC3436176
Publikováno v:
Journal of Biochemistry. 152:251-258
The metalloprotease ADAMTS13 affects platelet adhesion and aggregation through depolymerization of von Willebrand factor (VWF) multimers. Identification of ADAMTS13-binding proteins would reveal the hitherto unrecognized mechanisms underlying microva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688e1c39b5e576f9f0c11f682b3537c4
https://doi.org/10.1093/jb/mvs066
https://doi.org/10.1093/jb/mvs066
Autor:
Yasunori Okada, Hideyuki Okano, Hitoshi Abe, Satsuki Mochizuki, Kenji Soejima, Aya Sasaki, Masayuki Shimoda, Hirotaka James Okano
Publikováno v:
JNCI: Journal of the National Cancer Institute. 104:906-922
BACKGROUND A disintegrin and metalloproteinase 28 (ADAM28) is implicated in tumor growth and metastasis in human breast and non-small cell lung carcinomas. We explored the mechanism of ADAM28-mediated metastasis by searching for new substrates of ADA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a478dfdce99eec06b28dabf92de6c7
https://doi.org/10.1093/jnci/djs232
https://doi.org/10.1093/jnci/djs232