Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kenji Morokuma"'
Autor:
Kenji Morokuma, Shuntaro Tsukamoto, Kyosuke Mori, Kei Miyako, Ryuichi Sakai, Raku Irie, Masato Oikawa
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 540-550 (2021)
Herein, we report the enantiospecific synthesis of two artificial glutamate analogs designed based on IKM-159, an antagonist selective to the AMPA-type ionotropic glutamate receptor. The synthesis features the chiral resolution of the carboxylic acid
Externí odkaz:
https://doaj.org/article/64bd65e9f4f64be6a6ee26614e63ddec
Autor:
Raku Irie, Ryuichi Sakai, Kyosuke Mori, Kei Miyako, Masato Oikawa, Kenji Morokuma, Shuntaro Tsukamoto
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 540-550 (2021)
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 540-550 (2021)
Herein, we report the enantiospecific synthesis of two artificial glutamate analogs designed based on IKM-159, an antagonist selective to the AMPA-type ionotropic glutamate receptor. The synthesis features the chiral resolution of the carboxylic acid
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 78:292-303
Herein we report enantiospecific synthesis of two artificial glutamate analogs designed based on IKM–159, an antagonist selective to AMPA-type ionotropic glutamate receptor. The synthesis features chiral resolution of the carboxylic acid intermedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bdbaeef7444910fc8afa230af940d74
https://doi.org/10.3762/bxiv.2020.45.v1
https://doi.org/10.3762/bxiv.2020.45.v1
Publikováno v:
Tetrahedron Letters. 60:2067-2069
Efficient stereodivergent syntheses of (+)-lycoperdic acid (LPA) and 4-epi-LPA have been achieved based on asymmetric hydrogenation (H2, Rh/(R,S)-MeBoPhoz) of racemic enamide as a key step.
Autor:
Hiyori Itagaki, Ryuichi Sakai, Kei Miyako, Kenji Morokuma, Shuntaro Tsukamoto, Yuichi Ishikawa, Masato Oikawa
Publikováno v:
HETEROCYCLES. 101:91
Autor:
Yuko Taira, Yumiko Uehara, Keisuke Takahashi, Jun Ishihara, Susumi Hatakeyama, Kenji Morokuma, Setsuya Shibahara
Publikováno v:
Tetrahedron Letters. 49:6043-6045
Aldol reaction of di-tert-butyl 4-(4-methoxybenzyloxy)-2-oxobutanoate with pent-4-enal using (S)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(pyrrolidin-2-ylmethyl)thiourea hydrochloride as a catalyst, followed by Pinnick oxidation and tert-butyl esterifica
Autor:
Yuko Taira, Jun Ishihara, Setsuya Shibahara, Yumiko Uehara, Kenji Morokuma, Keisuke Takahashi, Susumi Hatakeyama
Publikováno v:
ChemInform. 40
Aldol reaction of di-tert-butyl 4-(4-methoxybenzyloxy)-2-oxobutanoate with pent-4-enal using (S)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(pyrrolidin-2-ylmethyl)thiourea hydrochloride as a catalyst, followed by Pinnick oxidation and tert-butyl esterifica
Autor:
Keisuke Takahashi, Susumi Hatakeyama, Ayako Nakano, Jun Ishihara, Mari Nakatani, Sakie Kawahara, Yoshiharu Iwabuchi, Kenji Morokuma, Saori Akamatsu
Publikováno v:
ChemInform. 37
Key features of the β-isocupreidine (β-ICD)-catalyzed asymmetric Baylis–Hillman reaction of aldehydes with 1,1,1,3,3,3-hexafluoroisopropyl acrylate (HFIPA) are presented. In addition, an improved method using azeotropically dried β-ICD is descri
Publikováno v:
ChemInform. 36
Viridiofungin A, a member of amino alkyl citrate antibiotics from Trichoderma viride, was enantioselectively synthesized in naturally occurring form for the first time, employing regio- and stereoselective opening of the chiral glycidate with vinylma