Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Kenji Mizutani"'
Autor:
Kenta Arai, Masaki Okumura, Young-Ho Lee, Hidekazu Katayama, Kenji Mizutani, Yuxi Lin, Sam-Yong Park, Kaichiro Sawada, Masao Toyoda, Hironobu Hojo, Kenji Inaba, Michio Iwaoka
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Seleno-insulin, a class of artificial insulin analogs, in which one of the three disulfide-bonds (S-S’s) of wild-type insulin (Ins) is replaced by a diselenide-bond (Se-Se), is attracting attention for its unique chemical and physiological
Externí odkaz:
https://doaj.org/article/3b226a8eb62b476ba0aaef9ad91a6b1c
Autor:
Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R. H. Tame, Asuka Inoue, Sam-Yong Park
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Neutrophil granulocytes play key roles in innate immunity and shaping adaptive immune responses. They are attracted by chemokines to sites of infection and tissue damage, where they kill and phagocytose bacteria. The chemokine CXCL8 (also kn
Externí odkaz:
https://doaj.org/article/9500ed9fae22491794b96977a5dbac6c
Autor:
Rawiwan Wongnak, Subbaian Brindha, Takahiro Yoshizue, Sawaros Onchaiya, Kenji Mizutani, Yutaka Kuroda
Publikováno v:
Biophysics and Physicobiology, Vol 20 (2023)
Low-cost bacterial production of the receptor binding domain (RBD) of the SARS-CoV-2 Omicron spike protein holds significant potential in expediting the development of therapeutics against COVID-19. However, RBD contains eight cysteines forming four
Externí odkaz:
https://doaj.org/article/819f364e4fc448989118ac605516667c
Autor:
Kenichi Kamata, Kenji Mizutani, Katsuya Takahashi, Roberta Marchetti, Alba Silipo, Christine Addy, Sam-Yong Park, Yuki Fujii, Hideaki Fujita, Tsuyoshi Konuma, Takahisa Ikegami, Yasuhiro Ozeki, Jeremy R. H. Tame
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract SeviL is a recently isolated lectin found to bind to the linear saccharides of the ganglioside GM1b (Neu5Ac $$\alpha$$ α (2-3)Gal $$\beta$$ β (1-3)GalNAc $$\beta$$ β (1-4)Gal $$\beta$$ β (1-4)Glc) and its precursor, asialo-GM1 (Gal $$\be
Externí odkaz:
https://doaj.org/article/b60abb2e47eb4f1aadf04cd6577a2ac0
Autor:
Shuqiong Wu, Takuya Sakamoto, Kentaro Oishi, Toru Sato, Kenichi Inoue, Takeshi Fukuda, Kenji Mizutani, Hiroyuki Sakai
Publikováno v:
IEEE Access, Vol 7, Pp 168484-168494 (2019)
Vital-sign estimation using ultra-wideband (UWB) radar is preferable because it is contactless and less privacy-invasive. Recently, many approaches have been proposed for estimating heart rate from UWB radar data. However, their performance is still
Externí odkaz:
https://doaj.org/article/e9ebcca5b119418a968b714b184d7c99
Autor:
Sawaros Onchaiya, Tomonori Saotome, Kenji Mizutani, Jose C. Martinez, Jeremy R. H. Tame, Shun-ichi Kidokoro, Yutaka Kuroda
Publikováno v:
Molecules, Vol 27, Iss 9, p 2813 (2022)
PSD95-PDZ3, the third PDZ domain of the post-synaptic density-95 protein (MW 11 kDa), undergoes a peculiar three-state thermal denaturation (N ↔ In ↔ D) and is amyloidogenic. PSD95-PDZ3 in the intermediate state (I) is reversibly oligomerized (RO
Externí odkaz:
https://doaj.org/article/f72d3a7b048d47d8b2bf5bcaaa958c38
Autor:
Kano Suzuki, Kenji Mizutani, Shintaro Maruyama, Kazumi Shimono, Fabiana L. Imai, Eiro Muneyuki, Yoshimi Kakinuma, Yoshiko Ishizuka-Katsura, Mikako Shirouzu, Shigeyuki Yokoyama, Ichiro Yamato, Takeshi Murata
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
V1-ATPases are rotary molecular motors that are powered by ATP hydrolysis. Here, the authors report two of the missing rotary states of this protein complex, and perform biochemical analysis to investigate the binding mode of the nucleotides.
Externí odkaz:
https://doaj.org/article/5851f81ae2544c9da73cb1883a72a8dc
Autor:
Suhaila Rahman, Ichiro Yamato, Shinya Saijo, Kenji Mizutani, Yoshiko Ishizuka-Katsura, Noboru Ohsawa, Takaho Terada, Mikako Shirouzu, Shigeyuki Yokoyama, So Iwata, Takeshi Murata
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55704 (2013)
Peripheral stalk subunits of eukaryotic or mammalian vacuolar ATPases (V-ATPases) play key roles in regulating its assembly and disassembly. In a previous study, we purified several subunits and their isoforms of the peripheral stalk region of Homo s
Externí odkaz:
https://doaj.org/article/c540dc9b071547f798fa61cc56b570e2
Autor:
Md Jahangir Alam, Satoshi Arai, Shinya Saijo, Kano Suzuki, Kenji Mizutani, Yoshiko Ishizuka-Katsura, Noboru Ohsawa, Takaho Terada, Mikako Shirouzu, Shigeyuki Yokoyama, So Iwata, Yoshimi Kakinuma, Ichiro Yamato, Takeshi Murata
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74291 (2013)
Vacuolar ATPases (V-ATPases) function as proton pumps in various cellular membrane systems. The hydrophilic V1 portion of the V-ATPase is a rotary motor, in which a central-axis DF complex rotates inside a hexagonally arranged catalytic A3B3 complex
Externí odkaz:
https://doaj.org/article/7ce6aa0c250c47519ec4ac08b05364f9
Autor:
Masaki Okumura, Tsubura Kuramochi, Yuxi Lin, Ran Furukawa, Kenji Mizutani, Takeshi Yokoyama, Mingeun Kim, Mi Hee Lim, Hyon-Seung Yi, Kenta Arai, Hiroshi Yamaguchi, Hironobu Hojo, Michio Iwaoka, Yoshikazu Tanaka, Sam-Yong Park, Kenji Inaba, Shingo Kanemura, Young-Ho Lee
SUMMARYDeeper understanding of the mechanism of the action of insulin and insulin-degrading enzyme (IDE) is a central theme in research into physiology and the pathophysiology of type 2 diabetes mellitus. Despite significant progress regarding the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::436273a9f9f1804be89afb86cfdd5bb9
https://doi.org/10.1101/2023.04.08.536135
https://doi.org/10.1101/2023.04.08.536135
