Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kenji Kuroiwa"'
Autor:
Kaoru Tominaga, Eiji Sakashita, Katsumi Kasashima, Kenji Kuroiwa, Yasumitsu Nagao, Naoki Iwamori, Hitoshi Endo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2113 (2023)
Epigenetic regulation via epigenetic factors in collaboration with tissue-specific transcription factors is curtail for establishing functional organ systems during development. Brain development is tightly regulated by epigenetic factors, which are
Externí odkaz:
https://doaj.org/article/bca3041ac50a4521b705f60baeee8e28
Autor:
Rintaro Kuroda, Kaoru Tominaga, Katsumi Kasashima, Kenji Kuroiwa, Eiji Sakashita, Hiroko Hayakawa, Tom Kouki, Nobuhiko Ohno, Kensuke Kawai, Hitoshi Endo
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255355 (2021)
Mitochondrial dysfunction is significantly associated with neurological deficits and age-related neurological diseases. While mitochondria are dynamically regulated and properly maintained during neurogenesis, the manner in which mitochondrial activi
Externí odkaz:
https://doaj.org/article/1c51f28caef64a06b51191bcef97f2be
Autor:
Nobuhiko Ohno, Rintaro Kuroda, Katsumi Kasashima, Hiroko Hayakawa, Kensuke Kawai, Hitoshi Endo, Tom Kouki, Kenji Kuroiwa, Eiji Sakashita, Kaoru Tominaga
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0255355 (2021)
PLoS ONE, Vol 16, Iss 7, p e0255355 (2021)
Mitochondrial dysfunction is significantly associated with neurological deficits and age-related neurological diseases. While mitochondria are dynamically regulated and properly maintained during neurogenesis, the manner in which mitochondrial activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18358e14ae40bc50999c8cfa2c9b024d
http://europepmc.org/articles/PMC8318236
http://europepmc.org/articles/PMC8318236
Autor:
Yoji Hakamata, Kenji Kuroiwa, Masaru Ichida, Yasumitsu Nagao, Satoshi Yamamoto, Hitoshi Endo, Fumiko Saito-Ohara, Kaoru Tominaga
Publikováno v:
Transgenic Research. 23:757-765
We developed a transgenic mouse line with Y chromosome-linked green fluorescent protein expressing transgenes (Y-GFP) by the conventional microinjection into the pronucleus of C57BL/6J fertilized oocytes. Embryonic stem (ES) cells derived from Y-GFP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdabc4d469b1bdd8a95f871e4ac46e1d
https://doi.org/10.1007/s11248-014-9813-0
https://doi.org/10.1007/s11248-014-9813-0
Autor:
Tohru Matsuura, Hitoshi Endo, Kenji Kuroiwa, Katsumi Kasashima, Takafumi Mashiko, Yasuyuki Nozaki, Eiji Sakashita, Kaoru Tominaga, Toshiro Hamamoto
Publikováno v:
The Journal of biological chemistry. 291(29)
Cytoplasmic protein aggregates are one of the pathological hallmarks of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Several RNA-binding proteins have been identified as comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9a7f5bc63541e3abbd0b8347a989ac
https://pubmed.ncbi.nlm.nih.gov/27226551
https://pubmed.ncbi.nlm.nih.gov/27226551
Autor:
Kazushi Morimoto, Kenji Kuroiwa, Satoshi Tanaka, Hiroyuki Tabata, Tomoaki Inazumi, Yukihiko Sugimoto, Eri Segi-Nishida, Noriyuki Hatae, Akiko Yano, Atsushi Ichikawa, Kumiko Yamaoka
Publikováno v:
Biochemical and Biophysical Research Communications. 389:678-682
We previously demonstrated that prostaglandin EP3 receptor augments EP2-elicited cAMP formation in COS-7 cells in a G i/o -insensitive manner. The purpose of our current study was to identify the signaling pathways involved in EP3-induced augmentatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c998a5cafea9b6d57b96a05a7516f1
https://doi.org/10.1016/j.bbrc.2009.09.064
https://doi.org/10.1016/j.bbrc.2009.09.064
Autor:
Toshiyuki Matsuoka, Chengcan Yao, Kenji Kuroiwa, Yoshiyasu Esaki, Shuh Narumiya, Yukihiko Sugimoto, Daiji Sakata, Youxian Li
Publikováno v:
Nature Medicine. 15:633-640
Prostaglandins play a key role in inflammation in a variety of settings. Now, Shuh Narumiya and colleagues show that prostaglandin E2 drives the production of inflammatory T helper cells, and that this can be blocked by inhibiting its EP4 receptor su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5097475f1f52b4c2ce39e48fa0ba5f32
https://doi.org/10.1038/nm.1968
https://doi.org/10.1038/nm.1968
Autor:
Fumio Sugawara, Toshiaki Aoki, Yasushi Shibata, Shinji Kamisuki, Kuniaki Kimoto, Susumu Kobayashi, Atsuo Nakazaki, Kouji Kuramochi, Nobuo Watanabe, Kenji Kuroiwa, Takao Arai
Publikováno v:
The Journal of Antibiotics. 60:614-621
Neoechinulin A, an alkaloid from Eurotium rubrum Hiji025, protected neuronal PC12 cells against cell death induced by peroxynitrite derived from SIN-1 (3-(4-morpholinyl)sydnonimine hydrochloride). In this study, we investigated the structure-activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c567a6b574e51ae5abb5bfffa66e797
https://doi.org/10.1038/ja.2007.79
https://doi.org/10.1038/ja.2007.79
Autor:
Masaaki Kimoto, Kensuke Ohnishi, Takashi Ohuchi, Susumu Kobayashi, Toshiaki Aoki, Shinji Kamisuki, Fumio Sugawara, Yoshifumi Takeda, Takao Arai, Atsuo Nakazaki, Yoichi Takakusagi, Kouji Kuramochi, Kenji Kuroiwa
Publikováno v:
Synlett. :0677-0680
A total synthesis of neoechinulin A was accomplished with high enantiomeric excess. Our total synthesis of neoechinulin A established the absolute configuration of natural neoechinulin A. The synthetic route features aldol condensation of a 3-formyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a531cb269316ad36751b0a522d126b5
https://doi.org/10.1055/s-2006-933113
https://doi.org/10.1055/s-2006-933113
Autor:
Jérôme Pène, Shin-ichi Tominaga, Donghui Ni, Rong Chen, Arun Subramaniam, Hans Yssel, Sefik S. Alkan, Vera Boulay, Nathalie Lecointe, Kenji Kuroiwa, Sandrine Lécart
Publikováno v:
European Journal of Immunology. 32:2979-2987
The T1/ST2 gene encodes, as a result of differential splicing, a cell surface protein (transmembrane form of T1/ST2, ST2L) and a soluble, secreted, protein (ST2). Here, we show that transcripts for both ST2L and ST2 are present in activated human Th2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac5f934f285e540f540cb29a8f6a8d35
https://doi.org/10.1002/1521-4141(2002010)32:10<2979::aid-immu2979>3.0.co
https://doi.org/10.1002/1521-4141(2002010)32:10<2979::aid-immu2979>3.0.co