Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Kenji Ichikawa"'
Autor:
Shuntaro Tsukamoto, Naoko Hata Sugi, Kyoko Nishibata, Youya Nakazawa, Daisuke Ito, Sayo Fukushima, Takayuki Nakagawa, Kenji Ichikawa, Yu Kato, Dai Kakiuchi, Aya Goto, Machiko Itoh-Yagi, Tomoki Aota, Satoshi Inoue, Yoshinobu Yamane, Norio Murai, Hiroshi Azuma, Satoshi Nagao, Ken Sasai, Tsuyoshi Akagi, Toshio Imai, Junji Matsui, Tomohiro Matsushima
Publikováno v:
Molecular Cancer Therapeutics. 22:12-24
Innate and adaptive resistance to cancer therapies, such as chemotherapies, molecularly targeted therapies, and immune-modulating therapies, is a major issue in clinical practice. Subpopulations of tumor cells expressing the receptor tyrosine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a10c1095ce2e3a366410096239706cb
https://doi.org/10.1158/1535-7163.mct-21-0879
https://doi.org/10.1158/1535-7163.mct-21-0879
Autor:
Yasuhiro Funahashi, Yu Kato, Akira Yokoi, Saori Watanabe Miyano, Masahiro Matsuki, Kotaro Kodama, Takayuki Kimura, Satoshi Goda, Shogo Yamaguchi, Yoichi Ozawa, Sayo Fukushima, Kenji Ichikawa, Hiroshi Kamiyama, Yusuke Adachi
Supplementary Figure S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf8008b4dd99f042df43b0531622a53
https://doi.org/10.1158/0008-5472.22582421.v1
https://doi.org/10.1158/0008-5472.22582421.v1
Autor:
Yasuhiro Funahashi, Yu Kato, Akira Yokoi, Saori Watanabe Miyano, Masahiro Matsuki, Kotaro Kodama, Takayuki Kimura, Satoshi Goda, Shogo Yamaguchi, Yoichi Ozawa, Sayo Fukushima, Kenji Ichikawa, Hiroshi Kamiyama, Yusuke Adachi
Supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818c7d9361caacc73c3ad61690108abc
https://doi.org/10.1158/0008-5472.22582424.v1
https://doi.org/10.1158/0008-5472.22582424.v1
Autor:
Yasuhiro Funahashi, Yu Kato, Akira Yokoi, Saori Watanabe Miyano, Masahiro Matsuki, Kotaro Kodama, Takayuki Kimura, Satoshi Goda, Shogo Yamaguchi, Yoichi Ozawa, Sayo Fukushima, Kenji Ichikawa, Hiroshi Kamiyama, Yusuke Adachi
Combination therapies consisting of immune checkpoint inhibitors plus anti-VEGF therapy show enhanced antitumor activity and are approved treatments for patients with renal cell carcinoma (RCC). The immunosuppressive roles of VEGF in the tumor microe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbc68c88bc7972d1c7e4f5c9c7a4b1b
https://doi.org/10.1158/0008-5472.c.6570578
https://doi.org/10.1158/0008-5472.c.6570578
Autor:
Tomohiro Matsushima, Junji Matsui, Toshio Imai, Tsuyoshi Akagi, Ken Sasai, Satoshi Nagao, Hiroshi Azuma, Norio Murai, Yoshinobu Yamane, Satoshi Inoue, Tomoki Aota, Machiko Itoh-Yagi, Aya Goto, Dai Kakiuchi, Yu Kato, Kenji Ichikawa, Takayuki Nakagawa, Sayo Fukushima, Daisuke Ito, Youya Nakazawa, Kyoko Nishibata, Naoko Hata Sugi, Shuntaro Tsukamoto
Supplementary Data Figure S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027266325de598a360e70cebdb70ac13
https://doi.org/10.1158/1535-7163.22523445.v1
https://doi.org/10.1158/1535-7163.22523445.v1
Autor:
Tomohiro Matsushima, Junji Matsui, Toshio Imai, Tsuyoshi Akagi, Ken Sasai, Satoshi Nagao, Hiroshi Azuma, Norio Murai, Yoshinobu Yamane, Satoshi Inoue, Tomoki Aota, Machiko Itoh-Yagi, Aya Goto, Dai Kakiuchi, Yu Kato, Kenji Ichikawa, Takayuki Nakagawa, Sayo Fukushima, Daisuke Ito, Youya Nakazawa, Kyoko Nishibata, Naoko Hata Sugi, Shuntaro Tsukamoto
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c23bcdea8a75df937d669803564f73a
https://doi.org/10.1158/1535-7163.22523442
https://doi.org/10.1158/1535-7163.22523442
Autor:
Shuntaro, Tsukamoto, Naoko Hata, Sugi, Kyoko, Nishibata, Youya, Nakazawa, Daisuke, Ito, Sayo, Fukushima, Takayuki, Nakagawa, Kenji, Ichikawa, Yu, Kato, Dai, Kakiuchi, Aya, Goto, Machiko, Itoh-Yagi, Tomoki, Aota, Satoshi, Inoue, Yoshinobu, Yamane, Norio, Murai, Hiroshi, Azuma, Satoshi, Nagao, Ken, Sasai, Tsuyoshi, Akagi, Toshio, Imai, Junji, Matsui, Tomohiro, Matsushima
Publikováno v:
Molecular cancer therapeutics.
Innate and adaptive resistance to cancer therapies, such as chemotherapies, molecularly targeted therapies, and immune-modulating therapies, is a major issue in clinical practice. Subpopulations of tumor cells expressing the receptor tyrosine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21539d8f860e5eef92e13fe771eac470
https://pubmed.ncbi.nlm.nih.gov/36279567
https://pubmed.ncbi.nlm.nih.gov/36279567
Co-stimulatory molecules decide T cell fate through regulations of their invigoration and impairment
Autor:
Kenji Ichikawa, Kazuhisa Ichikawa
T cell invigoration is an essential step for eliminating pathogens and cancer cells. Co-stimulatory molecules, such as CD80, CD86, and ICOSLG reinforce TCR stimuli for T cell activations. Despite identifying multiple co-stimulatory molecules, the dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa47b0e06bac6325ec52dc796abca15
https://doi.org/10.1101/2022.09.21.508809
https://doi.org/10.1101/2022.09.21.508809
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine derivatives as novel selective Axl inhibitors
Autor:
Takayuki Nakagawa, Kyoko Nishibata, Takashi Ueno, Yu Kato, Yoshinobu Yamane, Norio Murai, Sayo Fukushima, Satoshi Inoue, Hiroshi Azuma, Aya Goto, Tomohiro Matsushima, Junji Matsui, Shuntaro Tsukamoto, Naoko Hata Sugi, Nagao Satoshi, Daisuke Ito, Kenji Ichikawa, Dai Kakiuchi
Publikováno v:
Bioorganicmedicinal chemistry letters. 48
Axl and Mer are members of the TAM (Tyro3-Axl-Mer) family of receptor tyrosine kinases. Previously, we reported that enzyme-mediated inhibition of Mer by an Axl/Mer dual inhibitor led to retinal toxicity in mice, whereas selective Axl inhibition by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804e749fff17a865645c4416313eca4c
https://pubmed.ncbi.nlm.nih.gov/34271070
https://pubmed.ncbi.nlm.nih.gov/34271070
Autor:
Nagao Satoshi, Yoshinobu Yamane, Tomohiro Matsushima, Junji Matsui, Dai Kakiuchi, Norio Murai, Shuntaro Tsukamoto, Satoshi Inoue, Takayuki Nakagawa, Yu Kato, Sayo Fukushima, Kyoko Nishibata, Hiroshi Azuma, Daisuke Ito, Kenji Ichikawa, Naoko Hata Sugi, Aya Goto, Takashi Ueno
Publikováno v:
Bioorganicmedicinal chemistry. 39
Axl and Mer are a members of the TAM (Tyro3-Axl-Mer) family of receptor tyrosine kinases, which, when activated, can promote tumor cell survival, proliferation, migration, invasion, angiogenesis, and tumor-host interactions. Chronic inhibition of Mer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3092cd3774e7188997ce78d86c061c0b
https://pubmed.ncbi.nlm.nih.gov/33930844
https://pubmed.ncbi.nlm.nih.gov/33930844