Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kenji IRIMURA"'
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 47:38-42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53edfac453bb58cb6fc130bbc10c5a14
https://doi.org/10.5649/jjphcs.47.38
https://doi.org/10.5649/jjphcs.47.38
Autor:
Toshimatsu Maeda, Naomasa Asaka, Naosuke Matsuura, Kenji Irimura, Tsukasa Kirimoto, Yukio Hayashi
Publikováno v:
Cardiovascular Drug Reviews. 17:75-86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93ae36c0c27eb24e358f3d5a34b214ff
https://doi.org/10.1111/j.1527-3466.1999.tb00005.x
https://doi.org/10.1111/j.1527-3466.1999.tb00005.x
Autor:
Kenji Irimura, Tetsuhiro Goto, Yasuhide Kouchi, Taiji Hayashi, Akinobu Ohuchida, Yasuo Yoshizawa, Kenji Moriyama, Hidenobu Morinaga
Publikováno v:
Toxicology. 217:233-239
Diamine oxidase (DAO; EC 1.4.3.6), which catabolizes a variety of substrates including histamine and diamines, is the degradative enzyme of the catabolic pathway of polyamines found in high activity in the mature upper villus cells of the rat intesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a144e069d08b70e88ee3bad480fb29ae
https://doi.org/10.1016/j.tox.2005.09.017
https://doi.org/10.1016/j.tox.2005.09.017
Publikováno v:
Journal of Controlled Release. 88:35-42
Polyethylene glycol-modified liposomes (PEGylated liposomes) represent promising carrier systems for therapeutic agents. Herein, we report on a study of the effect of repeated injection of PEGylated liposomes on their pharmacokinetics in rats. The fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aa45952c8e8e72fa00a15869fbe3d0
https://doi.org/10.1016/s0168-3659(02)00462-5
https://doi.org/10.1016/s0168-3659(02)00462-5
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:783-786
To enhance the therapeutic efficacy as well as to reduce the side effect, we attempted to liposomalize 4beta-aminoalkyl-4'-O-demethyl-4-desoxypodophyllotoxin (TOP-53), a novel and effective topoisomerase II inhibitor. More than 90% of TOP-53 was effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980c05ab9a2723e5ffa743447180acf6
https://doi.org/10.1248/bpb.25.783
https://doi.org/10.1248/bpb.25.783
Publikováno v:
Journal of Toxicologic Pathology. 14:305-308
A very uncommon myxoid liposarcoma was found in a 41-week-old Crj:CD(SD)IGS male rat. At necropsy, an encapsulated elastic mass was observed in the subcutis of the left cervical region. The cut-surface was whitish, translucent and myxomatous with foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665757d962b65cb4001bb7c79a596abf
https://doi.org/10.1293/tox.14.305
https://doi.org/10.1293/tox.14.305
Publikováno v:
岐阜藥科大學紀要 = The annual proceedings of Gifu College of Pharmacy. 49:45-52
MET-88,an inhibitor of γ-butyrobetaine hydroxylase, can be characterized as a unique cardioprotective agent for the treatment of congestive heart failure (CHF) with an ability to regulate the activity of SR Ca^-ATPase. MET-88 protected the hypoxic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::432a6823bca44a9ac0c48dc9e0cc591a
http://id.nii.ac.jp/1076/00012042/
http://id.nii.ac.jp/1076/00012042/
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 39:221-228
Alcohol consumption causes acute alcohol pancreatitis and worsens the prognosis; however, there is no useful model for elucidation of the mechanism underlying this worsening. The aim of our study was to establish a new prognostic model of acute alcoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cacaaf3dd98ef7b6f6a38e497509039
https://doi.org/10.1016/s1056-8719(98)00026-4
https://doi.org/10.1016/s1056-8719(98)00026-4
ORAL SINGLE-DOSE TOXICITY STUDY OF A NEW ANTINEOPLASTIC AGENT S-1, AND ITS COMPONENTS, CDHP, AND OXO
Publikováno v:
The Journal of Toxicological Sciences. 21:495-504
S-1, an antineoplastic formulation of a fluorinated pyrimidine derivative containing tegafur (FT), CDHP, and potassium oxonate (Oxo) in a molar ratio of 1:0.4:1, was recently developed by Taiho Pharmaceutical Co., Ltd., with the aim of prolonging the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30d16297ce84f0d169a421b740b4517
https://doi.org/10.2131/jts.21.supplementiii_495
https://doi.org/10.2131/jts.21.supplementiii_495
Publikováno v:
Medical Electron Microscopy. 26:161-168
A total of 36 male F344 rats was fed a diet containing 1% aspirin or 0.25% clofibrate for 1, 3 and 4 weeks. Hepatomegaly was more evident with aspirin than with clofibrate. The activity of magnesium dependent adenosine triphosphatase (Mg-ATPase) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df2bc8aab3fbe37c3490d343bd789ca
https://doi.org/10.1007/bf02347995
https://doi.org/10.1007/bf02347995