Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Kenji Fukudome"'
Autor:
Niamh O'Regan, Kristina Gegenbauer, Eimear M. Gleeson, Kenji Fukudome, Jamie M. O'Sullivan, Clive Drakeford, Niall Dalton, Alain Chion, Teresa M. Brophy, Owen P. Smith, Roger J.S. Preston, James S. O'Donnell
Publikováno v:
Haematologica, Vol 107, Iss 8 (2022)
Externí odkaz:
https://doaj.org/article/915af75fe6c7477c8bc22b31031e043d
Autor:
Margarita Pérez-Casal, Colin Downey, Beatriz Cutillas-Moreno, Mirko Zuzel, Kenji Fukudome, Cheng Hock Toh
Publikováno v:
Haematologica, Vol 94, Iss 3 (2009)
Background The endothelial protein C receptor plays an important role within the protein C pathway in regulating coagulation and inflammation. Recently, we described that endothelial protein C receptor can be released in vitro in microparticulate for
Externí odkaz:
https://doaj.org/article/fc2fc715b8f146d9a7b7623aec77e098
Autor:
Niamh O'Regan, Kristina Gegenbauer, Eimear M. Gleeson, Kenji Fukudome, Jamie M. O'Sullivan, Clive Drakeford, Niall Dalton, Alain Chion, Teresa M. Brophy, Owen P. Smith, Roger J.S. Preston, James S. O'Donnell
Publikováno v:
Haematologica. 107(8)
Publikováno v:
Biochemical and Biophysical Research Communications. 511:318-322
The Kururu no β-glu® (KBG) is a commercial hydrothermal-treated Aureobasidium pullulans β-glucan produced by a unique hydrothermal process that results in high solubility of the β-glucan. In this study, we examined the biological activities of th
Publikováno v:
Polyhedron. 155:275-280
In this study, we succeeded in the crystal surface modification of metal–organic framework (MOF) with an organic polymer by site-specific radical polymerization. A MOF was selected with interpenetrated structure containing a naphthalenediimide moie
Autor:
Yoshitsugu Miyazaki, Hiroshi Mukae, Koichi Izumikawa, Kenji Fukudome, Kazuhiro Oshima, Katsunori Yanagihara, Naoki Iwanaga, Shigeru Kohno, Masafumi Seki, Taiga Miyazaki, Shigeki Nakamura
Publikováno v:
Infection and Immunity. 84:1986-1993
Chronic lower respiratory tract infection with Pseudomonas aeruginosa is difficult to treat due to enhanced antibiotic resistance and decreased efficacy of drug delivery to destroyed lung tissue. To determine the potential for restorative immunomodul
Autor:
Katsunori Yanagihara, Yoshifumi Imamura, Shigeki Nakamura, Akitaka Tanaka, Shigeru Kohno, Masafumi Seki, Naoki Iwanaga, Kenji Fukudome, Koichi Izumikawa, Taiga Miyazaki, Hiroshi Kakeya
Publikováno v:
Clinical and Vaccine Immunology. 20(7):977-985
Coinfection with bacteria is a major cause of mortality during influenza epidemics. Recently, Toll-like receptor (TLR) agonists were shown to have immunomodulatory functions. In the present study, we investigated the effectiveness and mechanisms of t
Autor:
Kiyoshi Takatsu, Uleng Bahrun, Shoichiro Ohta, Kenji Fukudome, Masao Kimoto, Yoshinori Nagai, Tsutomu Yanagibashi, Naoko Tsuneyoshi, Nurlaely Mida Rachmawati, Hiroki Tsukamoto
Publikováno v:
International Immunology. 25:117-128
Stimulation of Toll-like receptor 4 (TLR4) induces not only innate but also adaptive immune responses, and has been suggested to exert adjuvant effects. Additional to such positive effects, pre-stimulation of TLR4 induces endotoxin tolerance where an
Autor:
Hideyuki Ihara, Naoko Tsuneyoshi, Shoko Takao, Yoshitaka Ikeda, Masao Kimoto, Hiroki Tsukamoto, Kenji Fukudome
Publikováno v:
International Immunology. 24:495-506
Recognition of LPS by the toll-like receptor 4 (TLR4)/MD-2 complex is a trigger of innate immune defense against bacterial invasion. However, excessive immune activation by this receptor complex causes septic shock and autoimmunity. Manipulation of T
Publikováno v:
International Immunology. 22:271-280
Toll-like receptor (TLR) 4/MD-2 dimerization is thought to be required for the initiation of signaling during innate immune responses. In this study, we examined the molecular mechanisms underlying receptor dimerization in the context of accessory mo