Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Kenji F. Tanaka"'
Autor:
Masanori Dantsuji, Ayako Mochizuki, Kiyomi Nakayama, Mitsuko Kanamaru, Masahiko Izumizaki, Kenji F. Tanaka, Tomio Inoue, Shiro Nakamura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The serotonergic system modulates the neural circuits involved in jaw movement; however, the role of serotonin (5-HT) neurons in masticatory movement remains unclear. Here, we investigated the effect of selective activation of 5-HT neurons i
Externí odkaz:
https://doaj.org/article/80e1bd2e36e94e95a63fb8a8b7005d58
Autor:
Eiji Shigetomi, Hideaki Suzuki, Yukiho J. Hirayama, Fumikazu Sano, Yuki Nagai, Kohei Yoshihara, Keisuke Koga, Toru Tateoka, Hideyuki Yoshioka, Youichi Shinozaki, Hiroyuki Kinouchi, Kenji F. Tanaka, Haruhiko Bito, Makoto Tsuda, Schuichi Koizumi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Reactive astrocytes play a pivotal role in the pathogenesis of neurological diseases; however, their functional phenotype and the downstream molecules by which they modify disease pathogenesis remain unclear. Here, we genetically increase P2
Externí odkaz:
https://doaj.org/article/2557cf6cc7f6489ba3fc0d968dc92110
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Serotonin is a neuromodulator that affects multiple behavioral and cognitive functions. Nonetheless, how serotonin causes such a variety of effects via brain-wide projections and various receptors remains unclear. Here we measured brain-wide
Externí odkaz:
https://doaj.org/article/cf8c2855689e4d14beb95770d0312cf6
Autor:
Masakazu Taira, Kayoko W. Miyazaki, Katsuhiko Miyazaki, Jianning Chen, Shiho Okitsu-Sakurayama, Anupama Chaudhary, Mika Nishio, Tsukasa Miyake, Akihiro Yamanaka, Kenji F. Tanaka, Kenji Doya
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Serotonin is an essential neuromodulator that affects behavioral and cognitive functions. Previous studies have shown that activation of serotonergic neurons in the dorsal raphe nucleus (DRN) promotes patience to wait for future rewards. However, it
Externí odkaz:
https://doaj.org/article/ad2312408b904ab7be04e73aad115ea3
Publikováno v:
Neuropsychopharmacology Reports, Vol 43, Iss 3, Pp 414-424 (2023)
Abstract Contrary to the previous notion that the dorsomedial striatum (DMS) is crucial for acquiring new learning, accumulated evidence has suggested that the DMS also plays a role in the execution of already learned action sequences. Here, we exami
Externí odkaz:
https://doaj.org/article/69bf7b1876044c19a837d778ca6a8ab7
Autor:
Yusaku Katada, Hiromitsu Kunimi, Naho Serizawa, Deokho Lee, Kenta Kobayashi, Kazuno Negishi, Hideyuki Okano, Kenji F. Tanaka, Kazuo Tsubota, Toshihide Kurihara
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 1-13 (2023)
Ectopic induction of optogenetic actuators, such as channelrhodopsin, is a promising approach to restoring vision in the degenerating retina. However, the cell type-specific response of ectopic photoreception has not been well understood. There are l
Externí odkaz:
https://doaj.org/article/2eb99aaf89804103af13347c0cff9850
Autor:
Takahito Uchida, Yuki Sugiura, Eiji Sugiyama, Rae Maeda, Kenji F. Tanaka, Makoto Suematsu, Masaru Mimura, Hiroyuki Uchida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The lack of biomarkers to monitor and predict the efficacy of electroconvulsive therapy (ECT) has hindered its optimal use. To establish metabolomic markers for monitoring and predicting the treatment efficacy of ECT, we comprehensively eval
Externí odkaz:
https://doaj.org/article/357e1c150bb74e01bb081ff18a5e29db
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2024)
The progressive ratio (PR) lever-press task serves as a benchmark for assessing goal-oriented motivation. However, a well-recognized limitation of the PR task is that only a single data point, known as the breakpoint, is obtained from an entire sessi
Externí odkaz:
https://doaj.org/article/230e85854e4d481a932f6ab70f1f14d6
Autor:
Yosuke Yawata, Yu Shikano, Jun Ogasawara, Kenichi Makino, Tetsuhiko Kashima, Keiko Ihara, Airi Yoshimoto, Shota Morikawa, Sho Yagishita, Kenji F. Tanaka, Yuji Ikegaya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract In some models, animals approach aversive stimuli more than those housed in an enriched environment. Here, we found that male mice in an impoverished and unstimulating (i.e., boring) chamber without toys sought aversive air puffs more often
Externí odkaz:
https://doaj.org/article/18fe229e9a1c4b60872f1cf7fc0dbbe9
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Mural cells are critical components of the cerebral vasculature. They are categorized into three primary subsets: arteriole smooth muscle cells (aSMCs), pericytes (PCs) and venule smooth muscle cells (vSMCs). It is well known that aSMCs can directly
Externí odkaz:
https://doaj.org/article/cf237573ac9a4b09860fce412f5ad03c