Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Kenji, Arimitsu"'
Autor:
Marina Omokawa, Hiroyuki Kimura, Kenji Arimitsu, Yusuke Yagi, Yasunao Hattori, Hidekazu Kawashima, Yuki Naito, Hiroyuki Yasui
Publikováno v:
ACS Omega, Vol 9, Iss 1, Pp 879-886 (2023)
Externí odkaz:
https://doaj.org/article/99902efc2fae4c00a43c77a1b070cc17
Autor:
Minoru Ozeki, Aya Niki, Naoto Kojima, Kenji Arimitsu, Hiroki Iwasaki, Manabu Node, Shinzo Hosoi, Akiko Kuse, Takashi Shigeta, Shiho Nakagawa, Shui Aoki, Masayuki Yamashita, Ikuo Kawasaki, Tetsuya Kajimoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:926-930
Acyclic asymmetric quaternary stereocenters, which are composed of four carbon-carbon bonds, were finely constructed by utilizing a face-selective alkylation of enolate intermediates derived from an asymmetric Michael addition reaction of a chiral li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dc3278dcd8ec6466cdf6550b17ab17
https://doi.org/10.1248/cpb.c21-00436
https://doi.org/10.1248/cpb.c21-00436
Publikováno v:
Chemistry Letters. 50:1470-1474
As sugars form complexes with boronic acids, some sugars are used as additives for boron-containing pharmaceuticals. The binding constants of the rare sugar d-allulose with boronic acids were measu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253e430ebbf004774cd54851f33cc995
https://doi.org/10.1246/cl.210181
https://doi.org/10.1246/cl.210181
Autor:
Hidekazu Kawashima, Takenori Furukawa, Kenji Arimitsu, Hiroyuki Yasui, Yusuke Yagi, Hanae Torimoto, Hiroyuki Kimura
Publikováno v:
ACS Med Chem Lett
[Image: see text] Erythropoietin-producing hepatocellular (Eph) receptors are receptor tyrosine kinases involved in cell–cell contact. The EphA2 receptor is associated with cancer proliferation and migration. Therefore, EphA2 receptor imaging has t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700bface4a3ab2a467259cc8c9dcdd28
https://doi.org/10.1021/acsmedchemlett.1c00030
https://doi.org/10.1021/acsmedchemlett.1c00030
Autor:
Hiroyuki Kimura, Kenji Tomatsu, Hidekazu Saiki, Kenji Arimitsu, Masahiro Ono, Hidekazu Kawashima, Ren Iwata, Hiroaki Nakanishi, Eiichi Ozeki, Yuji Kuge, Hideo Saji
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159303 (2016)
In the field of positron emission tomography (PET) radiochemistry, compact microreactors provide reliable and reproducible synthesis methods that reduce the use of expensive precursors for radiolabeling and make effective use of the limited space in
Externí odkaz:
https://doaj.org/article/5743f0c40bc94f748c73ffa52e83e305
Publikováno v:
Handbook of In Vivo Chemistry in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2165b497e0974c906ce15a91f62606a1
https://doi.org/10.1002/9783527344406.ch6
https://doi.org/10.1002/9783527344406.ch6
Autor:
Hiroyuki Kusuhara, Hiroyuki Kimura, Shinya Kagawa, Kenji Arimitsu, Hideo Saji, Masahiro Ono, Kaori Togashi, Tatsuya Higashi, Kazuya Maeda, Yuji Nakamoto, Mutsumi Mikamo, Ryuichi Nishii, Yusuke Yagi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:317-324
Quantitative evaluations of the functions of uptake and efflux transporters directly in vivo is desired to understand an efficient hepatobiliary transport of substrate drugs. Pitavastatin is a substrate of organic anion transporting polypeptides (OAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7469bc18e0ab36753a4fe6522e0079cd
https://doi.org/10.1016/j.dmpk.2019.05.006
https://doi.org/10.1016/j.dmpk.2019.05.006
Autor:
Hidekazu Kawashima, Daisuke Mori, Hiroyuki Kimura, Masahiro Ono, Yusuke Yagi, Kenji Arimitsu, Hideo Saji
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:4200-4210
Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels that have been implicated in higher brain functions. To elucidate the functional mechanisms underlying nAChRs and contribute significantly to development of drugs tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3c2129134cc08becd02ecebc019825
https://doi.org/10.1016/j.bmc.2019.07.053
https://doi.org/10.1016/j.bmc.2019.07.053
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:2245-2252
We have designed (S)-(5-(azetidin-2-ylmethoxy)pyridine-3-yl)methyl cyclopentadienyltricarbonyl technetium carboxylate ([99mTc]CPTT–A–E) with high affinity for nicotinic acetylcholine receptors (nAChRs) using (2(S)-azetidinylmethoxy)-pyridine (A-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ade4da6668a98b1f6a278728704df6
https://doi.org/10.1016/j.bmc.2019.04.030
https://doi.org/10.1016/j.bmc.2019.04.030
Autor:
Minoru Ozeki, Shinzo Hosoi, Naoto Kojima, Takashi Shigeta, Akihiro Nakamura, Hiroki Iwasaki, Ikuo Kawasaki, Aya Niki, Ayano Horie, Hideki Mizutani, Masayuki Yamashita, Tetsuya Kajimoto, Kenji Arimitsu, Ayumi Hachino, Natsuko Kobayashi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:71-74
A facile and convenient synthesis of trisubstituted (E)-α,β-unsaturated esters was developed by improving our previously established method. The new method circumvented the separation of the intermediates, which have an activating group of the hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d505c5707c068c53f4ec56fac6858b
https://doi.org/10.1248/cpb.c18-00666
https://doi.org/10.1248/cpb.c18-00666