Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis.

Autor: Hassoun Y; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Aptekmann AA; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Keniya MV; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Gomez RY; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Alayo N; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Novi G; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Quinteros C; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Kaya F; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Zimmerman M; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Caceres DH; Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, The Netherlands.; Studies in Translational Microbiology and Emerging Diseases (MICROS) Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia., Chow NA; Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Perlin DS; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America.; Hackensack Meridian School of Medicine, Nutley, New Jersey, United States of America.; Georgetown University Lombardi Comprehensive Cancer Center, Washington, D.C., United States of America., Shor E; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America.; Hackensack Meridian School of Medicine, Nutley, New Jersey, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Sep 09; Vol. 20 (9), pp. e1012521. Date of Electronic Publication: 2024 Sep 09 (Print Publication: 2024).

Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris .

Autor: Toepfer S; Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand., Lackner M; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Keniya MV; Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand.; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ 07110, USA., Zenz LM; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Friemert M; Center for Drug Research, Department of Pharmacy, Ludwig-Maximilian University of Munich, 81377 Munich, Germany., Bracher F; Center for Drug Research, Department of Pharmacy, Ludwig-Maximilian University of Munich, 81377 Munich, Germany., Monk BC; Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2023 Jun 13; Vol. 9 (6). Date of Electronic Publication: 2023 Jun 13.

Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target.

Autor: Ruma YN; Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand., Keniya MV; Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand.; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ 07110, USA., Monk BC; Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2022 Nov 28; Vol. 8 (12). Date of Electronic Publication: 2022 Nov 28.

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67.

Autor: Monk BC; Department of Oral Sciences, Sir John Walsh Research Institute, University of Otago, Dunedin 9016, New Zealand., Keniya MV; Department of Oral Sciences, Sir John Walsh Research Institute, University of Otago, Dunedin 9016, New Zealand.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2021 Nov 26; Vol. 7 (12). Date of Electronic Publication: 2021 Nov 26.

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases.

Autor: Monk BC; Department of Oral Sciences, Sir John Walsh Research Institute, University of Otago, Dunedin 9016, New Zealand., Keniya MV; Department of Oral Sciences, Sir John Walsh Research Institute, University of Otago, Dunedin 9016, New Zealand.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2021 Jan 20; Vol. 7 (2). Date of Electronic Publication: 2021 Jan 20.