Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Kenichiro Yata"'
Autor:
Akihiro Shindo, Hiroshi Tanemura, Kenichiro Yata, Kazuhide Hamada, Masunari Shibata, Yasuyuki Umeda, Fumio Asakura, Naoki Toma, Hiroshi Sakaida, Takao Fujisawa, Waro Taki, Hidekazu Tomimoto
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100045 (2014)
Inflammation is crucially involved in the development of carotid plaques. We examined the relationship between plaque vulnerability and inflammatory biomarkers using intraoperative blood and tissue specimens. We examined 58 patients with carotid sten
Externí odkaz:
https://doaj.org/article/e0512a026f7c4b88aa0cd626a954cebe
Autor:
Kumiko Kagawa, Ayako Nakano, Hirokazu Miki, Asuka Oda, Hiroe Amou, Kyoko Takeuchi, Shingen Nakamura, Takeshi Harada, Shiro Fujii, Kenichiro Yata, Shuji Ozaki, Toshio Matsumoto, Masahiro Abe
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31594 (2012)
TNF-related apoptosis-inducing ligand/Apo2 ligand (TRAIL/Apo2L) selectively induces apoptosis in various cancer cells including myeloma (MM) cells. However, the susceptibility of MM cells to TRAIL is largely low in most of MM cells by yet largely unk
Externí odkaz:
https://doaj.org/article/23327e8b385341959bac799d3daf14ee
Autor:
Kyoko Takeuchi, Masahiro Abe, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Shinsuke Kido, Takeshi Harada, Osamu Tanaka, Hirokazu Miki, Shingen Nakamura, Ayako Nakano, Kumiko Kagawa, Kenichiro Yata, Shuji Ozaki, Toshio Matsumoto
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9870 (2010)
BACKGROUND: Multiple myeloma (MM) expands almost exclusively in the bone marrow and generates devastating bone lesions, in which bone formation is impaired and osteoclastic bone resorption is enhanced. TGF-beta, a potent inhibitor of terminal osteobl
Externí odkaz:
https://doaj.org/article/1c16fdab5fd14332a7cc2a2f64d95ecc
Autor:
Tetsu Kawabata, Kazuhiko Fujita, Hiroki Iida, Shujie Wang, Woo Kim, Takanobu Otsuka, Go Sakai, Haruhiko Tokuda, Akira Mizoguchi, Kenichiro Yata, Gen Kuroyanagi, Rie Matsushima-Nishiwaki, Osamu Kozawa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Incretins, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), secreted from enteroendocrine cells after food ingestion, are currently recognized to regulate glucose metabolism through insulin secretion.
Autor:
Takuya Shimada, Hideaki Wakita, Hidekazu Tomimoto, Hirofumi Matsuyama, Kenichiro Yata, Ryosuke Takahashi, Akihiro Shindo
Publikováno v:
Brain Research. 1736:146779
Inflammation plays an important role in acute and chronic cerebral ischemia. Recent reports indicate that the inflammatory response triggered by tissue damage is mediated by a multiple-protein complex called the inflammasome. The NOD-like receptor fa
Autor:
Kenichiro Yata, Akihiro Shindo, Hideaki Wakita, Takakuni Maki, Atsushi Niwa, Hidekazu Tomimoto, Takuya Shimada, Takashi Ayaki, Hirofumi Matsuyama, Ryogen Sasaki
Publikováno v:
Neuroscience letters. 704
Alzheimer's disease (AD) is the most common type of dementia in aging adults. Increasing evidence has revealed that vascular risk factors influence the midlife development of AD and that diet-induced obesity accelerates tau phosphorylation in tau tra
Autor:
Akira Mizoguchi, Hidekazu Tomimoto, Yutaka Tomita, Norihiro Suzuki, Kenichiro Yata, Miyuki Unekawa, Toshio Tanaka, Yuhei Nishimura
Publikováno v:
Stroke. 45:3698-3703
Background and Purpose— Proper brain function is maintained by an integrated system called the neurovascular unit (NVU) comprised cellular and acellular elements. Although the individual features of specific neurovascular components are understood,
Autor:
Hidekazu Tomimoto, Kenichiro Yata
Publikováno v:
Neurology and Clinical Neuroscience. 2:129-134
“Cerebral small vessel disease” is a general term featuring a group of disease conditions with characteristic lesions affecting mainly small vessels in the brain, such as Binswanger's disease, leukoaraiosis and lacunar infarctions. Cerebral small
Publikováno v:
Brain Research. 1533:131-140
Transactivation-responsive DNA-binding protein 43 (TDP-43) is closely involved in the pathogenesis of frontotemporal lobar degeneration. The native form, but not phosphorylated form, of TDP-43 has been reported to redistribute during acute neuronal i
Autor:
Hidekazu Tomimoto, Kenichiro Yata, Junya Kuroyanagi, Beibei Zhang, Akira Tsuboyama, Takeshi Miyazaki, Tomoaki Ogiwara, Taichi Shintou, Zi Zhang, Kohei Watanabe, Tsuyoshi Nomoto, Miko Kawabata, Noriko Umemoto, Yuhei Nishimura, Takeshi Imamura, Toshio Tanaka, Yasuhito Shimada, Mie Okano
Publikováno v:
ACS Chemical Neuroscience. 4:1183-1193
Disruption of the blood-brain barrier (BBB) can occur in various pathophysiological conditions. Administration of extraneous tracers that can pass the disrupted, but not the intact, BBB and detection of the extravasation have been widely used to asse