Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kenichiro Kinouchi"'
Autor:
Shogo Sato, Tomoaki Hishida, Kenichiro Kinouchi, Fumiaki Hatanaka, Yumei Li, Quy Nguyen, Yumay Chen, Ping H. Wang, Kai Kessenbrock, Wei Li, Juan Carlos Izpisua Belmonte, Paolo Sassone-Corsi
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112590- (2023)
Summary: Distinct metabolic conditions rewire circadian-clock-controlled signaling pathways leading to the de novo construction of signal transduction networks. However, it remains unclear whether metabolic hallmarks unique to pluripotent stem cells
Externí odkaz:
https://doaj.org/article/635f84e16f77448088b48fad1fd43bac
Autor:
Akihito Hishikawa, Kaori Hayashi, Akiko Kubo, Kazutoshi Miyashita, Akinori Hashiguchi, Kenichiro Kinouchi, Norifumi Yoshimoto, Ran Nakamichi, Riki Akashio, Erina Sugita, Tatsuhiko Azegami, Toshiaki Monkawa, Makoto Suematsu, Hiroshi Itoh
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103436- (2021)
Summary: The “preconditioning effect” in AKI is a phenomenon in which an episode of ischemia-reperfusion results in tolerance to subsequent ischemia-reperfusion injury. However, its relationship between DNA damage repair has not been elucidated.
Externí odkaz:
https://doaj.org/article/b9104add2d57440785cf3e54283a323b
Autor:
Genki Ichihara, Yoshinori Katsumata, Hidenori Moriyama, Hiroki Kitakata, Akeo Hirai, Mizuki Momoi, Seien Ko, Yoshiki Shinya, Kenichiro Kinouchi, Eiji Kobayashi, Motoaki Sano
Publikováno v:
Heliyon, Vol 7, Iss 11, Pp e08359- (2021)
Drinking hydrogen (H2)-rich water is a common way to consume H2. Although many studies have shown efficacy of drinking H2-rich water in neuropsychiatric and endocrine metabolic disorders, their authenticity has been questioned because none examined t
Externí odkaz:
https://doaj.org/article/18f1ce5df400448887a9371e6b6b7ca3
Autor:
Ebru Aras, Giorgio Ramadori, Kenichiro Kinouchi, Yu Liu, Rafael M. Ioris, Xavier Brenachot, Sanda Ljubicic, Christelle Veyrat-Durebex, Silvia Mannucci, Mirco Galié, Pierre Baldi, Paolo Sassone-Corsi, Roberto Coppari
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2385-2398.e3 (2019)
Summary: Loss of synchrony between geophysical time and insulin action predisposes to metabolic diseases. Yet the brain and peripheral pathways linking proper insulin effect to diurnal changes in light-dark and feeding-fasting inputs are poorly under
Externí odkaz:
https://doaj.org/article/7bf84bd976e1468ca62e2d4016c78a01
Autor:
Kenichiro Kinouchi, Christophe Magnan, Nicholas Ceglia, Yu Liu, Marlene Cervantes, Nunzia Pastore, Tuong Huynh, Andrea Ballabio, Pierre Baldi, Selma Masri, Paolo Sassone-Corsi
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3299-3314.e6 (2018)
Summary: The circadian clock operates as intrinsic time-keeping machinery to preserve homeostasis in response to the changing environment. While food is a known zeitgeber for clocks in peripheral tissues, it remains unclear how lack of food influence
Externí odkaz:
https://doaj.org/article/e3137f0cfcd6413bba41d11827d87c39
Autor:
Atsuhiro Ichihara, Mariyo Sakoda, Asako Kurauchi-Mito, Tatsuya Narita, Kenichiro Kinouchi, Kanako Bokuda, Hiroshi Itoh
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 4, Pp 296-300 (2010)
Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage. The newly developed direct renin in
Externí odkaz:
https://doaj.org/article/46a8e8fe013f4fecb99d63e0354149c3
Autor:
Atsuhiro Ichihara, Mariyo Sakoda, Asako Kurauchi-Mito, Tatsuya Narita, Kenichiro Kinouchi, Hiroshi Itoh
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 20-23 (2009)
Discovery of the (pro)renin receptor uncovered a novel function of renin/prorenin as the receptor ligands in addition to the enzyme and its precursor. The bindings of renin and prorenin to the (pro)renin receptor trigger two major pathways: the angio
Externí odkaz:
https://doaj.org/article/bf540f257d594673b3316b8dc0e8ecce
Autor:
Kenichiro Kinouchi, Atsuhiro Ichihara, Motoaki Sano, Ge-Hong Sun-Wada, Yoh Wada, Hiroki Ochi, Toru Fukuda, Kanako Bokuda, Hideaki Kurosawa, Naohiro Yoshida, Shu Takeda, Keiichi Fukuda, Hiroshi Itoh
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78603 (2013)
The ATPase 6 accessory protein 2 (ATP6AP2)/(pro)renin receptor (PRR) is essential for the biogenesis of active vacuolar H(+)-ATPase (V-ATPase). Genetic deletion of ATP6AP2/PRR causes V-ATPase dysfunction and compromises vesicular acidification. Here,
Externí odkaz:
https://doaj.org/article/83fefe0b3de8487583369a879995f052
Publikováno v:
International Journal of Hypertension, Vol 2011 (2011)
Background/Aims. Arterial stiffness is an independent risk factor for cardiovascular morbidity and mortality. This study was conducted to determine the effect of olmesartan (OLM) and azelnidipine (AZL) on arterial stiffness using the cardio-ankle vas
Externí odkaz:
https://doaj.org/article/7c3c61d9def742d1b182925097de45c3
Autor:
Kenichiro Kinouchi, Yosuke Mizutani, Toshifumi Nakamura, Shintaro Yamaguchi, Koichiro Homma, Sakiko Kobayashi, Kazutoshi Miyashita, Isao Kurihara, Hirotaka Shibata, Hiroshi Itoh
Publikováno v:
Journal of Hypertension. 41:e437-e438